SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lw5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 5lw5 RNA REPLICASE
POLYPROTEIN
(Turnip
yellow
mosaic
virus) 		5 / 12 GLY A 850
GLN A 837
PHE A 836
ILE A 806
PHE A 749
 None
 1.42A 1p93D-5lw5A:
undetectable		 1p93D-5lw5A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 5lw5 RNA REPLICASE
POLYPROTEIN
(Turnip
yellow
mosaic
virus) 		4 / 6 PHE A 749
PHE A 764
ALA A 831
LEU A 803
 None
 1.03A 4ejgD-5lw5A:
undetectable		 4ejgD-5lw5A:
16.88