SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lwg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 5lwg VP3
(Israeli
acute
paralysis
virus) 		3 / 3 ALA C  17
VAL C  15
TRP C  18
 None
 0.90A 1bdwA-5lwgC:
undetectable
1bdwB-5lwgC:
undetectable		 1bdwA-5lwgC:
5.29
1bdwB-5lwgC:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 5lwg VP3
(Israeli
acute
paralysis
virus) 		5 / 12 GLN C 175
ALA C  82
VAL C  90
GLY C  89
ALA C 183
 None
 1.06A 1kxhA-5lwgC:
undetectable		 1kxhA-5lwgC:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 5lwg VP3
VP4
(Israeli
acute
paralysis
virus) 		4 / 6 THR D  50
GLY C  41
ASP C  42
ILE D  42
 None
 0.86A 3w9tF-5lwgD:
undetectable		 3w9tF-5lwgD:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 5lwg VP3
(Israeli
acute
paralysis
virus) 		4 / 5 GLY C  84
ILE C  81
LYS C  79
GLN C 175
 None
 1.16A 4ma8C-5lwgC:
undetectable		 4ma8C-5lwgC:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5lwg VP3
(Israeli
acute
paralysis
virus) 		3 / 3 GLN C  78
ILE C  91
HIS C  67
 None
 0.63A 5z12B-5lwgC:
undetectable		 5z12B-5lwgC:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5lwg VP3
(Israeli
acute
paralysis
virus) 		3 / 3 ASN C 197
VAL C 256
HIS C 149
 None
 0.76A 6a5yD-5lwgC:
undetectable		 6a5yD-5lwgC:
13.58