SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lwi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 5lwi STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		5 / 10 LEU B 205
GLU B 210
PRO B 110
ALA B 120
GLY B 118
 None
 1.35A 1mjqC-5lwiB:
undetectable
1mjqD-5lwiB:
undetectable		 1mjqC-5lwiB:
18.07
1mjqD-5lwiB:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5lwi STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		4 / 8 THR B 221
PRO B 222
VAL B 223
ALA B 146
 None
 0.84A 2v32A-5lwiB:
undetectable
2v32B-5lwiB:
undetectable		 2v32A-5lwiB:
22.59
2v32B-5lwiB:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5lwi STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		4 / 7 TYR B 203
VAL B 133
TYR B 196
ILE B 246
 None
 1.35A 2xz5B-5lwiB:
undetectable
2xz5E-5lwiB:
undetectable		 2xz5B-5lwiB:
21.40
2xz5E-5lwiB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5lwi STRUCTURAL
POLYPROTEIN
(Israeli
acute
paralysis
virus) 		4 / 7 ASN B  87
TYR B 103
TYR B 216
LEU B 151
 None
 1.23A 4yv5A-5lwiB:
undetectable		 4yv5A-5lwiB:
17.75