SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lwy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 5lwy V REGION HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 107
 None
 0.28A 4m7kH-5lwyH:
23.1		 4m7kH-5lwyH:
69.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 5lwy V REGION HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL H  18
ILE H  20
VAL H 114
THR H 112
 None
 0.70A 4xdtA-5lwyH:
0.7		 4xdtA-5lwyH:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5lwy V REGION HEAVY CHAIN
(Mus
musculus) 		4 / 7 VAL H  37
TRP H  47
PHE H  70
GLU H  99
 None
 1.40A 5unxA-5lwyH:
undetectable
5unxB-5lwyH:
undetectable		 5unxA-5lwyH:
13.83
5unxB-5lwyH:
13.83