SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lyn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 5lyn SMALL GLUTAMINE-RICH
TETRATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 187
LYS A 218
VAL A 219
 None
 0.95A 1l2iA-5lynA:
undetectable		 1l2iA-5lynA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 5lyn SMALL GLUTAMINE-RICH
TETRATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 180
LEU A 176
ALA A 179
 None
 0.74A 4iizA-5lynA:
undetectable		 4iizA-5lynA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 5lyn SMALL GLUTAMINE-RICH
TETRATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 180
LEU A 176
ALA A 179
 None
 0.72A 4ikiA-5lynA:
undetectable		 4ikiA-5lynA:
19.12