SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5lz6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 5lz6 GOLGI RESIDENT
PROTEIN GCP60
(Homo
sapiens) 		3 / 3 ASP A 477
PHE A 433
LEU A 505
 None
 0.63A 2zi9A-5lz6A:
undetectable		 2zi9A-5lz6A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 5lz6 GOLGI RESIDENT
PROTEIN GCP60
(Homo
sapiens) 		4 / 4 PRO A 499
TYR A 504
GLY A 502
THR A 436
 None
 1.08A 3ib0A-5lz6A:
undetectable		 3ib0A-5lz6A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 5lz6 GOLGI RESIDENT
PROTEIN GCP60
3A
(Homo
sapiens;
Aichivirus
B) 		3 / 3 GLU A 401
GLY A 398
SER B   4
 None
 0.60A 4b53B-5lz6A:
2.4		 4b53B-5lz6A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 5lz6 GOLGI RESIDENT
PROTEIN GCP60
(Homo
sapiens) 		3 / 3 ARG A 485
ASP A 426
ARG A 484
 None
BGC  A 601 (-3.0A)
BGC  A 601 (-4.5A)
 0.62A 4wq4B-5lz6A:
undetectable		 4wq4B-5lz6A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 5lz6 3A
GOLGI RESIDENT
PROTEIN GCP60
(Aichivirus
B;
Homo
sapiens) 		5 / 12 SER B  13
ASP B  16
TYR A 525
SER A 393
GLU B  22
 None
 1.38A 5iqbA-5lz6B:
undetectable		 5iqbA-5lz6B:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 5lz6 3A
GOLGI RESIDENT
PROTEIN GCP60
(Aichivirus
B;
Homo
sapiens) 		5 / 11 SER B  13
ASP B  16
TYR A 525
SER A 393
GLU B  22
 None
 1.36A 5iqeA-5lz6B:
undetectable		 5iqeA-5lz6B:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		 5lz6 3A
GOLGI RESIDENT
PROTEIN GCP60
(Aichivirus
B;
Homo
sapiens) 		5 / 12 SER B  13
ASP B  16
TYR A 525
SER A 393
GLU B  22
 None
 1.37A 5iqeC-5lz6B:
undetectable		 5iqeC-5lz6B:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 5lz6 3A
GOLGI RESIDENT
PROTEIN GCP60
(Aichivirus
B;
Homo
sapiens) 		5 / 12 SER B  13
ASP B  16
TYR A 525
SER A 393
GLU B  22
 None
 1.49A 5iqeD-5lz6B:
undetectable		 5iqeD-5lz6B:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5lz6 GOLGI RESIDENT
PROTEIN GCP60
(Homo
sapiens) 		4 / 5 PRO A 499
GLY A 500
TYR A 498
VAL A 503
 None
 1.24A 5x80C-5lz6A:
undetectable
5x80D-5lz6A:
undetectable		 5x80C-5lz6A:
19.44
5x80D-5lz6A:
19.44