SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3
(Saccharomyces
cerevisiae) 		4 / 6 ILE D 125
ARG D  49
THR D  53
LEU D  55
 None
 0.98A 2einN-5m0jD:
4.0
2einW-5m0jD:
undetectable		 2einN-5m0jD:
21.41
2einW-5m0jD:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3
(Saccharomyces
cerevisiae) 		4 / 7 ASP D 227
ILE D 144
ASN D 114
PHE D 110
 None
 1.15A 2jc9A-5m0jD:
undetectable		 2jc9A-5m0jD:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3
(Saccharomyces
cerevisiae) 		4 / 6 PHE D  92
PHE D 208
THR D  13
VAL D  17
 None
 1.20A 3lb3A-5m0jD:
undetectable		 3lb3A-5m0jD:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3
(Saccharomyces
cerevisiae) 		4 / 6 PHE D  92
PHE D 208
THR D  13
VAL D  17
 None
 1.17A 3lb3B-5m0jD:
undetectable		 3lb3B-5m0jD:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3
(Saccharomyces
cerevisiae) 		4 / 7 ASN D 114
LEU D 136
LEU D 226
PHE D 110
 None
 1.24A 3nk2X-5m0jD:
undetectable		 3nk2X-5m0jD:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3
(Saccharomyces
cerevisiae) 		4 / 4 ILE D 194
ASN D 193
ILE D 178
VAL D 174
 None
 1.24A 4uy87-5m0jD:
undetectable		 4uy87-5m0jD:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3
(Saccharomyces
cerevisiae) 		5 / 10 GLN D 122
LEU D 121
LEU D 117
LEU D  35
LEU D 136
 None
 1.05A 4yiaA-5m0jD:
undetectable		 4yiaA-5m0jD:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3
(Saccharomyces
cerevisiae) 		5 / 12 LEU D 121
ASP D 145
LEU D  55
LEU D  35
LEU D 113
 None
 1.24A 5nfjB-5m0jD:
undetectable		 5nfjB-5m0jD:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3
(Saccharomyces
cerevisiae) 		5 / 12 LEU D 121
ASP D 145
LEU D  55
LEU D  35
LEU D 113
 None
 1.26A 5nfjC-5m0jD:
undetectable		 5nfjC-5m0jD:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3
(Saccharomyces
cerevisiae) 		3 / 3 HIS D  33
SER D  29
ARG D  63
 None
None
C  E  27 ( 3.2A)
 1.03A 5u63A-5m0jD:
undetectable		 5u63A-5m0jD:
20.71