SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m0o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		4 / 6 PRO A 338
PHE A 341
GLU A 376
VAL A 372
 None
 1.31A 1l2iB-5m0oA:
undetectable		 1l2iB-5m0oA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		3 / 3 PHE A 256
TYR A  21
TYR A 321
 None
 1.03A 1x70B-5m0oA:
undetectable		 1x70B-5m0oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_A_IPHA2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		4 / 5 HIS A 259
TYR A 289
TYR A 405
PRO A 290
 None
 1.48A 2ombA-5m0oA:
undetectable
2ombB-5m0oA:
undetectable		 2ombA-5m0oA:
17.97
2ombB-5m0oA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		4 / 8 ILE A 170
TYR A  21
ASP A 171
ARG A 174
 EPA  A 502 (-4.3A)
None
None
None
 0.90A 2v57A-5m0oA:
undetectable		 2v57A-5m0oA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		4 / 8 ILE A 170
TYR A  21
ASP A 171
ARG A 174
 EPA  A 502 (-4.3A)
None
None
None
 0.90A 2v57C-5m0oA:
undetectable		 2v57C-5m0oA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		5 / 12 THR A 147
ALA A 150
LEU A 197
LEU A 240
MET A 166
 None
 1.08A 3hm1A-5m0oA:
2.2		 3hm1A-5m0oA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		3 / 3 ASP A 239
ARG A  95
ARG A 245
 None
None
EPA  A 502 (-3.8A)
 1.05A 3k37A-5m0oA:
undetectable		 3k37A-5m0oA:
20.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		4 / 5 LEU A  78
ARG A 245
PRO A 246
ALA A 249
 None
EPA  A 502 (-3.8A)
EPA  A 502 ( 3.7A)
HEM  A 501 (-3.9A)
 0.38A 3vm4A-5m0oA:
55.7		 3vm4A-5m0oA:
37.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		5 / 9 VAL A  49
VAL A  48
VAL A 308
ILE A 310
GLY A 315
 None
 1.09A 4fwdA-5m0oA:
undetectable		 4fwdA-5m0oA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		5 / 12 LEU A 247
MET A 103
LEU A 102
ILE A 374
ILE A 373
 HEM  A 501 (-4.4A)
None
None
None
None
 1.03A 4j24A-5m0oA:
undetectable		 4j24A-5m0oA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		5 / 12 LEU A 247
MET A 103
LEU A 102
ILE A 374
ILE A 373
 HEM  A 501 (-4.4A)
None
None
None
None
 1.03A 4j24B-5m0oA:
undetectable		 4j24B-5m0oA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		4 / 5 VAL A 390
LEU A 395
VAL A 406
PHE A 410
 None
 0.97A 4lb0B-5m0oA:
undetectable		 4lb0B-5m0oA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		5 / 10 LEU A 142
LEU A 141
ILE A 374
THR A 123
HIS A 120
 None
None
None
None
SO4  A 503 (-3.8A)
 1.30A 4mk4A-5m0oA:
undetectable		 4mk4A-5m0oA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		4 / 6 VAL A  16
LEU A  17
LEU A  41
PHE A  58
 None
 0.83A 4o1zA-5m0oA:
0.4		 4o1zA-5m0oA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE
(Jeotgalicoccus
sp.
ATCC
8456) 		5 / 12 LEU A  22
GLY A  20
TRP A 330
ASP A 350
ILE A 352
 None
 0.96A 6mhtA-5m0oA:
undetectable		 6mhtA-5m0oA:
21.69