SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m0q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 5m0q INTEGRASE
(Visna-maedi
virus) 		5 / 11 VAL A  91
TYR A  67
GLU A  89
LEU A 182
VAL A  65
 None
 1.24A 1i9jH-5m0qA:
undetectable
1i9jL-5m0qA:
undetectable		 1i9jH-5m0qA:
22.49
1i9jL-5m0qA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 5m0q INTEGRASE
(Visna-maedi
virus) 		4 / 7 ASP A  66
ASP A 118
GLN A 148
GLU A 154
 None
 1.15A 3l2vA-5m0qA:
17.6		 3l2vA-5m0qA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 5m0q INTEGRASE
(Visna-maedi
virus) 		4 / 8 ASP A  66
ASP A 118
PRO A 144
GLU A 154
 None
 0.89A 3oyaA-5m0qA:
17.4		 3oyaA-5m0qA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 5m0q INTEGRASE
(Visna-maedi
virus) 		4 / 8 ASP A  66
ASP A 118
GLY A 120
GLU A 154
 None
 0.78A 3s3mA-5m0qA:
17.6		 3s3mA-5m0qA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 5m0q INTEGRASE
(Visna-maedi
virus) 		4 / 8 ASP A  66
ASP A 118
GLY A 120
GLU A 154
 None
 0.78A 3s3nA-5m0qA:
17.4		 3s3nA-5m0qA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 5m0q INTEGRASE
(Visna-maedi
virus) 		4 / 7 ASP A  66
ASP A 118
GLN A 148
GLU A 154
 None
 1.29A 3s3oA-5m0qA:
17.5		 3s3oA-5m0qA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 5m0q INTEGRASE
(Visna-maedi
virus) 		5 / 11 PHE A 201
GLY A  84
GLU A  80
ILE A  60
ASN A  82
 None
 1.37A 5hjiA-5m0qA:
undetectable		 5hjiA-5m0qA:
22.64