SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 PHE A 404
GLY A 419
PHE A 388
VAL A 378
LEU A 382
 None
 1.39A 1e3vA-5m11A:
undetectable		 1e3vA-5m11A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 8 ILE A 104
PHE A 146
LEU A 133
VAL A  96
 None
 0.86A 1fslB-5m11A:
undetectable		 1fslB-5m11A:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 6 PRO A 586
ASP A 498
ASN A 519
TRP A 500
 None
 1.22A 1hpkA-5m11A:
undetectable		 1hpkA-5m11A:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 10 LEU A 453
VAL A 442
VAL A 406
TYR A 425
GLY A 407
 None
 1.48A 1lw0A-5m11A:
undetectable		 1lw0A-5m11A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 11 LEU A 453
VAL A 442
VAL A 406
TYR A 425
GLY A 407
 None
 1.47A 1lwcA-5m11A:
undetectable		 1lwcA-5m11A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 9 LEU A 453
VAL A 442
VAL A 406
TYR A 425
GLY A 407
 None
 1.46A 1lwfA-5m11A:
undetectable		 1lwfA-5m11A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 ASP A 390
GLY A 412
GLU A 434
SER A 426
PHE A 414
 None
 1.28A 1maaA-5m11A:
undetectable		 1maaA-5m11A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 10 VAL A 116
LEU A 151
LEU A 142
TYR A  98
ALA A 118
 None
 1.29A 1pbcA-5m11A:
undetectable		 1pbcA-5m11A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 11 THR A 527
LEU A 516
VAL A 501
PHE A 488
VAL A 482
 None
 1.26A 1q23J-5m11A:
undetectable		 1q23J-5m11A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VRT_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 9 LEU A 453
VAL A 442
VAL A 406
TYR A 425
GLY A 407
 None
 1.43A 1vrtA-5m11A:
undetectable		 1vrtA-5m11A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 8 LYS A  70
ALA A  52
PHE A  51
LEU A 107
 None
 0.94A 2bxmA-5m11A:
undetectable		 2bxmA-5m11A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 MET A 554
ALA A 553
ASN A 490
GLY A 565
ILE A 551
 None
None
ZN  A 805 ( 4.8A)
None
None
 1.43A 2dcfA-5m11A:
undetectable		 2dcfA-5m11A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 10 LEU A 453
VAL A 442
VAL A 406
TYR A 425
GLY A 407
 None
 1.48A 2hnyA-5m11A:
undetectable		 2hnyA-5m11A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 9 GLY A 461
ILE A 464
VAL A 482
ILE A 503
VAL A 515
 None
 1.11A 2nnhB-5m11A:
undetectable		 2nnhB-5m11A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 5 VAL A 750
VAL A 707
GLY A 706
TRP A 740
 None
 0.99A 2p2fA-5m11A:
undetectable		 2p2fA-5m11A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 9 LEU A 712
GLU A 688
GLY A 680
GLY A 682
CYH A 716
 None
CA  A 810 (-2.1A)
None
None
None
 1.20A 2qmmA-5m11A:
undetectable		 2qmmA-5m11A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 8 HIS A 505
TYR A 552
THR A 609
GLN A 624
 None
 1.40A 2vxaF-5m11A:
undetectable
2vxaG-5m11A:
undetectable
2vxaI-5m11A:
undetectable		 2vxaF-5m11A:
6.72
2vxaG-5m11A:
6.72
2vxaI-5m11A:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 11 MET A 554
ALA A 553
ASN A 490
GLY A 565
ILE A 551
 None
None
ZN  A 805 ( 4.8A)
None
None
 1.40A 2zmaA-5m11A:
undetectable		 2zmaA-5m11A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 ARG A 424
LEU A 457
ASN A 389
VAL A 362
PHE A 416
 None
 1.05A 2zzmA-5m11A:
undetectable		 2zzmA-5m11A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 ARG A 424
LEU A 457
ASN A 389
VAL A 362
PHE A 416
 None
 1.07A 2zznA-5m11A:
undetectable		 2zznA-5m11A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 MET A 554
ALA A 553
ASN A 490
GLY A 565
ILE A 551
 None
None
ZN  A 805 ( 4.8A)
None
None
 1.41A 3a65A-5m11A:
undetectable		 3a65A-5m11A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A66_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 10 MET A 554
ALA A 553
ASN A 490
GLY A 565
ILE A 551
 None
None
ZN  A 805 ( 4.8A)
None
None
 1.39A 3a66A-5m11A:
0.9		 3a66A-5m11A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 5 PRO A 469
THR A 408
VAL A 442
GLY A 407
 None
 1.05A 3elzA-5m11A:
undetectable		 3elzA-5m11A:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 10 LEU A 453
VAL A 442
VAL A 406
TYR A 425
GLY A 407
 None
 1.47A 3lp1A-5m11A:
undetectable		 3lp1A-5m11A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 10 LEU A 453
VAL A 442
VAL A 406
TYR A 425
GLY A 407
 None
 1.46A 3qipA-5m11A:
undetectable		 3qipA-5m11A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWP_A_ACAA503_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 10 MET A 554
ALA A 553
ASN A 490
GLY A 565
ILE A 551
 None
None
ZN  A 805 ( 4.8A)
None
None
 1.40A 3vwpA-5m11A:
undetectable		 3vwpA-5m11A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 MET A 554
ALA A 553
ASN A 490
GLY A 565
ILE A 551
 None
None
ZN  A 805 ( 4.8A)
None
None
 1.40A 3vwqA-5m11A:
undetectable		 3vwqA-5m11A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWR_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 11 MET A 554
ALA A 553
ASN A 490
GLY A 565
ILE A 551
 None
None
ZN  A 805 ( 4.8A)
None
None
 1.40A 3vwrA-5m11A:
undetectable		 3vwrA-5m11A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		3 / 3 ASN A 617
ASP A 557
ASN A 559
 PG4  A 815 ( 4.8A)
None
None
 0.77A 4agaA-5m11A:
undetectable		 4agaA-5m11A:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 SER A 296
THR A 280
PHE A 282
SER A 317
PHE A 272
 None
 1.47A 4c49B-5m11A:
undetectable		 4c49B-5m11A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 4 LEU A 255
ILE A 224
GLY A 216
PHE A 226
 None
 1.14A 4dc3A-5m11A:
undetectable		 4dc3A-5m11A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 7 GLY A 231
ALA A 266
SER A 249
GLU A 267
 None
 0.81A 4hyfA-5m11A:
undetectable		 4hyfA-5m11A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 8 GLY A 231
ALA A 266
SER A 249
GLU A 267
 None
 0.81A 4hyfB-5m11A:
undetectable		 4hyfB-5m11A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 8 GLY A 231
ALA A 266
SER A 249
GLU A 267
 None
 0.86A 4hyfC-5m11A:
undetectable		 4hyfC-5m11A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 GLU A 274
LEU A 313
ARG A 260
ILE A 284
LEU A 311
 None
 1.17A 4j24D-5m11A:
undetectable		 4j24D-5m11A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 8 PRO A 243
MET A 211
PHE A 226
ILE A 224
 None
 1.01A 4j4vC-5m11A:
undetectable		 4j4vC-5m11A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 GLY A 680
GLY A 664
LEU A 666
SER A 683
ALA A 714
 None
 1.14A 4qtuB-5m11A:
undetectable		 4qtuB-5m11A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 11 ALA A 444
ASP A 390
TYR A 335
GLY A 458
GLY A 410
 None
 1.08A 4xp4A-5m11A:
undetectable		 4xp4A-5m11A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 11 LEU A 453
VAL A 442
VAL A 406
TYR A 425
GLY A 407
 None
 1.46A 5hbmA-5m11A:
undetectable		 5hbmA-5m11A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 GLY A 673
ASN A 332
ALA A  54
SER A  76
ILE A  75
 None
 1.18A 5igyA-5m11A:
undetectable		 5igyA-5m11A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		3 / 3 ASP A 610
ASN A 653
GLN A 624
 GOL  A 817 (-3.1A)
None
None
 0.77A 5k7uA-5m11A:
undetectable		 5k7uA-5m11A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 LEU A 485
GLY A 458
ASN A 463
PHE A 518
LEU A 516
 None
 1.35A 5kklB-5m11A:
undetectable		 5kklB-5m11A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 GLU A 274
LEU A 313
ARG A 260
ILE A 284
LEU A 311
 None
 1.08A 5toaB-5m11A:
undetectable		 5toaB-5m11A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 ASP A 393
SER A 566
PHE A 538
ALA A 588
ALA A 555
 None
 1.12A 5vc0A-5m11A:
undetectable		 5vc0A-5m11A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 10 PRO A 401
ALA A 395
GLY A 407
THR A 408
ILE A 445
 CAC  A 813 ( 4.7A)
None
None
None
None
 1.33A 5vyhA-5m11A:
undetectable		 5vyhA-5m11A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		4 / 5 VAL A 774
PRO A 696
GLY A 706
TYR A 703
 None
 1.43A 5x80A-5m11A:
undetectable
5x80B-5m11A:
undetectable		 5x80A-5m11A:
11.81
5x80B-5m11A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 7 VAL A 774
VAL A 694
PRO A 696
GLY A 706
TYR A 703
 None
 1.45A 5x80C-5m11A:
undetectable
5x80D-5m11A:
undetectable		 5x80C-5m11A:
11.81
5x80D-5m11A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		5 / 12 ASP A 333
HIS A 358
ASN A 332
GLU A  41
GLY A 328
 GOL  A 819 ( 2.5A)
ZN  A 807 ( 3.3A)
None
None
None
 1.45A 6gnfC-5m11A:
undetectable		 6gnfC-5m11A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93
(Porphyromonas
gingivalis) 		3 / 3 ASP A 152
SER A  94
SER A  89
 ZN  A 808 ( 2.3A)
None
None
 0.69A 6mxtA-5m11A:
undetectable		 6mxtA-5m11A:
22.32