SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
3 / 3 THR A  23
THR A  21
PRO A  19
None
0.80A 1a7yB-5m1mA:
undetectable
1a7yB-5m1mA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
3 / 3 THR A  21
PRO A  19
THR A  23
None
0.82A 1i3wE-5m1mA:
undetectable
1i3wE-5m1mA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
3 / 3 THR A  23
THR A  21
PRO A  19
None
0.76A 1qfiB-5m1mA:
undetectable
1qfiB-5m1mA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
3 / 3 THR A  21
PRO A  19
THR A  23
None
0.69A 209dC-5m1mA:
undetectable
209dC-5m1mA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
3 / 3 THR A  23
THR A  21
PRO A  19
None
0.85A 209dC-5m1mA:
undetectable
209dC-5m1mA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
5 / 11 ILE A  29
LEU A  48
ILE A  43
THR A  57
LEU A  14
None
1.23A 3a50C-5m1mA:
undetectable
3a50C-5m1mA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
5 / 12 ILE A  29
LEU A  48
ILE A  43
THR A  57
LEU A  14
None
1.26A 3a50E-5m1mA:
undetectable
3a50E-5m1mA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
5 / 11 SER A  27
ILE A  29
ALA A  39
SER A  38
LEU A  42
None
1.18A 3n8yA-5m1mA:
undetectable
3n8yA-5m1mA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
4 / 4 LEU A   6
ALA A 146
PHE A 104
ASN A 152
None
1.44A 3vaqA-5m1mA:
undetectable
3vaqA-5m1mA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
4 / 4 LEU A   6
ALA A 146
PHE A 104
ASN A 152
None
1.47A 3vasA-5m1mA:
undetectable
3vasA-5m1mA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
5 / 12 GLY A 102
GLY A 106
ASP A 103
LEU A 105
ALA A 100
None
1.16A 4lg1C-5m1mA:
undetectable
4lg1C-5m1mA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
5 / 12 ILE A  60
VAL A 125
VAL A 107
ALA A 146
LEU A 148
None
1.18A 4m11C-5m1mA:
undetectable
4m11C-5m1mA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
4 / 8 GLU A 108
ILE A   5
GLU A   9
ILE A 144
None
0.86A 4mj8A-5m1mA:
undetectable
4mj8A-5m1mA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)
5m1m MATRIX PROTEIN 1
(Influenza
C
virus)
5 / 12 ILE A 144
ILE A   7
ILE A  69
ARG A  63
ALA A  39
None
1.05A 5e72A-5m1mA:
undetectable
5e72A-5m1mA:
19.00