SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_A_BEZA11_0 (CES1 PROTEIN)	5m1q	PHAGE TERMINASE LARGE SUBUNIT (Thermus phage G20c)	4 / 4	LEU A 384 SER A 305 LEU A 266 LEU A 405	None	1.17A	1yajA-5m1qA: undetectable	1yajA-5m1qA: 15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD4_B_CHDB927_0 (FERROCHELATASE)	5m1q	PHAGE TERMINASE LARGE SUBUNIT (Thermus phage G20c)	3 / 3	LEU A 269 PRO A 270 ARG A 284	None	0.47A	2qd4B-5m1qA: undetectable	2qd4B-5m1qA: 19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD5_A_CHDA702_0 (FERROCHELATASE)	5m1q	PHAGE TERMINASE LARGE SUBUNIT (Thermus phage G20c)	3 / 3	LEU A 269 PRO A 270 ARG A 284	None	0.52A	2qd5A-5m1qA: 2.2	2qd5A-5m1qA: 19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_B_30BB500_2 (GENOME POLYPROTEIN)	5m1q	PHAGE TERMINASE LARGE SUBUNIT (Thermus phage G20c)	3 / 3	PHE A 304 TYR A 301 LEU A 307	None	0.76A	3keeB-5m1qA: undetectable	3keeB-5m1qA: 22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NXU_B_RITB600_1 (CYTOCHROME P450 3A4)	5m1q	PHAGE TERMINASE LARGE SUBUNIT (Thermus phage G20c)	5 / 12	ILE A 291 PHE A 304 ALA A 293 ILE A 355 ALA A 356	None	1.09A	3nxuB-5m1qA: undetectable	3nxuB-5m1qA: 17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_B_SUEB1201_2 (NS3 PROTEASE, NS4A PROTEIN)	5m1q	PHAGE TERMINASE LARGE SUBUNIT (Thermus phage G20c)	3 / 3	PHE A 304 TYR A 301 LEU A 307	None	0.70A	3sueB-5m1qA: undetectable	3sueB-5m1qA: 22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TWP_C_SALC404_1 (ANTHRANILATE PHOSPHORIBOSYLTRANSF ERASE)	5m1q	PHAGE TERMINASE LARGE SUBUNIT (Thermus phage G20c)	4 / 7	ALA A 342 TYR A 339 ARG A 284 ALA A 315	None	1.12A	3twpC-5m1qA: undetectable	3twpC-5m1qA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OAD_A_CLMA205_0 (GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794)	5m1q	PHAGE TERMINASE LARGE SUBUNIT (Thermus phage G20c)	5 / 12	ARG A 284 ALA A 313 GLY A 312 LEU A 307 TYR A 441	None	1.45A	4oadA-5m1qA: undetectable	4oadA-5m1qA: 26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VC0_A_RITA602_1 (CYTOCHROME P450 3A4)	5m1q	PHAGE TERMINASE LARGE SUBUNIT (Thermus phage G20c)	5 / 12	ILE A 291 PHE A 304 ALA A 293 ILE A 355 ALA A 356	None	1.14A	5vc0A-5m1qA: undetectable	5vc0A-5m1qA: 17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6R2E_E_FFOE403_0 (THYMIDYLATE SYNTHASE)	5m1q	PHAGE TERMINASE LARGE SUBUNIT (Thermus phage G20c)	5 / 12	ILE A 381 ASN A 383 LEU A 387 PHE A 408 ALA A 437	None	1.16A	6r2eE-5m1qA: undetectable	6r2eE-5m1qA: 20.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YAJ_A_BEZA11_0","CES1 PROTEIN","5m1q","PHAGE TERMINASE LARGE SUBUNIT","Thermus phage G20c",4,"LEU A 384;SER A 305;LEU A 266;LEU A 405","None","1.17A","1yajA-5m1qA:undetectable","1yajA-5m1qA:15.67"],["2QD4_B_CHDB927_0","FERROCHELATASE","5m1q","PHAGE TERMINASE LARGE SUBUNIT","Thermus phage G20c",3,"LEU A 269;PRO A 270;ARG A 284","None","0.47A","2qd4B-5m1qA:undetectable","2qd4B-5m1qA:19.22"],["2QD5_A_CHDA702_0","FERROCHELATASE","5m1q","PHAGE TERMINASE LARGE SUBUNIT","Thermus phage G20c",3,"LEU A 269;PRO A 270;ARG A 284","None","0.52A","2qd5A-5m1qA:2.2","2qd5A-5m1qA:19.22"],["3KEE_B_30BB500_2","GENOME POLYPROTEIN","5m1q","PHAGE TERMINASE LARGE SUBUNIT","Thermus phage G20c",3,"PHE A 304;TYR A 301;LEU A 307","None","0.76A","3keeB-5m1qA:undetectable","3keeB-5m1qA:22.01"],["3NXU_B_RITB600_1","CYTOCHROME P450 3A4","5m1q","PHAGE TERMINASE LARGE SUBUNIT","Thermus phage G20c",5,"ILE A 291;PHE A 304;ALA A 293;ILE A 355;ALA A 356","None","1.09A","3nxuB-5m1qA:undetectable","3nxuB-5m1qA:17.23"],["3SUE_B_SUEB1201_2","NS3 PROTEASE, NS4A PROTEIN","5m1q","PHAGE TERMINASE LARGE SUBUNIT","Thermus phage G20c",3,"PHE A 304;TYR A 301;LEU A 307","None","0.70A","3sueB-5m1qA:undetectable","3sueB-5m1qA:22.73"],["3TWP_C_SALC404_1","ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE","5m1q","PHAGE TERMINASE LARGE SUBUNIT","Thermus phage G20c",4,"ALA A 342;TYR A 339;ARG A 284;ALA A 315","None","1.12A","3twpC-5m1qA:undetectable","3twpC-5m1qA:18.80"],["4OAD_A_CLMA205_0","GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794","5m1q","PHAGE TERMINASE LARGE SUBUNIT","Thermus phage G20c",5,"ARG A 284;ALA A 313;GLY A 312;LEU A 307;TYR A 441","None","1.45A","4oadA-5m1qA:undetectable","4oadA-5m1qA:26.84"],["5VC0_A_RITA602_1","CYTOCHROME P450 3A4","5m1q","PHAGE TERMINASE LARGE SUBUNIT","Thermus phage G20c",5,"ILE A 291;PHE A 304;ALA A 293;ILE A 355;ALA A 356","None","1.14A","5vc0A-5m1qA:undetectable","5vc0A-5m1qA:17.15"],["6R2E_E_FFOE403_0","THYMIDYLATE SYNTHASE","5m1q","PHAGE TERMINASE LARGE SUBUNIT","Thermus phage G20c",5,"ILE A 381;ASN A 383;LEU A 387;PHE A 408;ALA A 437","None","1.16A","6r2eE-5m1qA:undetectable","6r2eE-5m1qA:20.12"]]