SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m2n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 777
ARG A 781
ILE A  10
 None
 0.87A 1a4gB-5m2nA:
4.9		 1a4gB-5m2nA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 SER A 464
GLU A 550
GLU A 552
 None
 0.55A 1eqbD-5m2nA:
undetectable		 1eqbD-5m2nA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 SER A 464
GLU A 550
GLU A 552
 None
 0.56A 1eqbB-5m2nA:
undetectable		 1eqbB-5m2nA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 402
ASP A 390
GLY A 772
ILE A 782
VAL A 388
 None
 0.98A 1k6cB-5m2nA:
undetectable		 1k6cB-5m2nA:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 479
GLY A 480
GLU A   8
ILE A 782
HIS A 430
 None
 1.25A 1kxhA-5m2nA:
undetectable		 1kxhA-5m2nA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 462
GLY A 556
ILE A 587
VAL A 586
 None
 0.76A 1p2yA-5m2nA:
undetectable		 1p2yA-5m2nA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 305
HIS A 290
ASP A 353
SER A 320
PHE A 355
 None
 1.45A 1uobA-5m2nA:
undetectable		 1uobA-5m2nA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 THR A  54
SER A 779
SER A 775
VAL A 773
 None
 1.00A 2hdnE-5m2nA:
undetectable
2hdnF-5m2nA:
undetectable
2hdnH-5m2nA:
undetectable		 2hdnE-5m2nA:
4.78
2hdnF-5m2nA:
18.83
2hdnH-5m2nA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 SER A 775
VAL A 773
THR A  54
SER A 779
 None
 1.01A 2hdnF-5m2nA:
undetectable
2hdnG-5m2nA:
undetectable
2hdnH-5m2nA:
undetectable		 2hdnF-5m2nA:
18.83
2hdnG-5m2nA:
4.78
2hdnH-5m2nA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 6 THR A  54
SER A 779
SER A 775
VAL A 773
 None
 1.01A 2hdnI-5m2nA:
undetectable
2hdnJ-5m2nA:
undetectable
2hdnL-5m2nA:
undetectable		 2hdnI-5m2nA:
4.78
2hdnJ-5m2nA:
18.83
2hdnL-5m2nA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 6 SER A 775
VAL A 773
THR A  54
SER A 779
 None
 0.99A 2hdnJ-5m2nA:
undetectable
2hdnK-5m2nA:
undetectable
2hdnL-5m2nA:
undetectable		 2hdnJ-5m2nA:
18.83
2hdnK-5m2nA:
4.78
2hdnL-5m2nA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 4 ASP A 387
ASP A 777
ASP A 406
GLY A  35
 None
 1.46A 2igtC-5m2nA:
undetectable		 2igtC-5m2nA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_D_AZZD1211_1
(DEOXYNUCLEOSIDE
KINASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 10 ILE A  12
VAL A  65
MET A  74
ALA A  31
PHE A  32
 None
 1.20A 2jj8D-5m2nA:
undetectable		 2jj8D-5m2nA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 240
ASN A 238
ARG A 268
 None
 0.89A 2qhfA-5m2nA:
undetectable		 2qhfA-5m2nA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 146
LEU A 156
ILE A 170
ILE A 128
PHE A 144
 None
 1.01A 2w9sA-5m2nA:
undetectable		 2w9sA-5m2nA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 146
LEU A 156
ILE A 170
ILE A 128
PHE A 144
 None
 0.99A 2w9sB-5m2nA:
undetectable		 2w9sB-5m2nA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 GLU A   3
ILE A 742
GLN A 744
ILE A 755
 None
 0.75A 2xkwA-5m2nA:
undetectable		 2xkwA-5m2nA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 SER A 623
LEU A 622
ALA A 659
THR A 672
ILE A 656
 None
 1.05A 3a35B-5m2nA:
undetectable		 3a35B-5m2nA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 SER A 623
LEU A 622
ALA A 659
THR A 672
ILE A 656
 None
 1.05A 3a3bA-5m2nA:
undetectable		 3a3bA-5m2nA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 5 PRO A  43
VAL A  30
THR A 361
GLY A 359
 None
 0.70A 3elzB-5m2nA:
undetectable		 3elzB-5m2nA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 169
GLY A 224
ILE A 170
SER A 157
LEU A 156
 None
 1.23A 3gyqB-5m2nA:
undetectable		 3gyqB-5m2nA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 755
VAL A 773
ARG A 781
TYR A 783
 None
 0.69A 3p6hA-5m2nA:
undetectable		 3p6hA-5m2nA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 626
ARG A 578
ILE A 655
 None
 0.68A 4b7qA-5m2nA:
6.5		 4b7qA-5m2nA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 626
ARG A 578
ILE A 655
 None
 0.42A 4b7qC-5m2nA:
9.0		 4b7qC-5m2nA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 SER A 223
GLN A 213
ILE A 235
PHE A 210
TRP A 289
 None
 1.47A 4c49B-5m2nA:
undetectable		 4c49B-5m2nA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 SER A 223
ILE A 235
PHE A 210
HIS A 212
TRP A 289
 None
 1.37A 4c49B-5m2nA:
undetectable		 4c49B-5m2nA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 287
LEU A 221
GLN A 295
GLU A 291
 None
 1.28A 4i41A-5m2nA:
undetectable		 4i41A-5m2nA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 711
TRP A 429
SER A 708
 None
 0.92A 4lrhA-5m2nA:
undetectable		 4lrhA-5m2nA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 100
ALA A  77
ASP A  22
PRO A  69
ILE A  85
 None
 1.07A 4m2xE-5m2nA:
undetectable		 4m2xE-5m2nA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 11 ASP A 777
VAL A  51
GLY A  35
SER A 779
GLY A 383
 None
 1.27A 4mm9A-5m2nA:
undetectable		 4mm9A-5m2nA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 ASP A 777
VAL A  51
GLY A  35
SER A 779
GLY A 383
 None
 1.33A 4mmbA-5m2nA:
undetectable		 4mmbA-5m2nA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 ASP A 777
VAL A  51
GLY A  35
SER A 779
GLY A 383
 None
 1.25A 4mmeA-5m2nA:
undetectable		 4mmeA-5m2nA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 9 ASP A 777
VAL A  51
GLY A  35
SER A 779
GLY A 383
 None
 1.25A 4mmeB-5m2nA:
undetectable		 4mmeB-5m2nA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 5 ILE A  38
PHE A  11
HIS A  58
ASP A 777
 None
 1.38A 4rzvB-5m2nA:
undetectable		 4rzvB-5m2nA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 659
LEU A 632
ILE A 587
ILE A 609
THR A 672
 None
 1.11A 4x5jA-5m2nA:
undetectable		 4x5jA-5m2nA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 11 ASP A 777
ALA A 752
VAL A  51
SER A 779
GLY A 383
 None
 1.11A 4xp4A-5m2nA:
undetectable		 4xp4A-5m2nA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 11 TYR A 732
PHE A 739
VAL A 671
ILE A 707
LEU A 724
 None
 1.16A 5huaA-5m2nA:
undetectable		 5huaA-5m2nA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 729
PRO A 751
ILE A 782
LEU A 400
LEU A 731
 None
 1.12A 5ienB-5m2nA:
2.9		 5ienB-5m2nA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		6 / 12 PRO A 751
VAL A 773
ILE A 391
ALA A 402
GLY A 723
ILE A 729
 None
 1.38A 5j2tC-5m2nA:
undetectable		 5j2tC-5m2nA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 739
GLN A 744
TYR A 783
LEU A 771
ILE A 720
 None
 0.78A 5y2tB-5m2nA:
undetectable		 5y2tB-5m2nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 11 ALA A   9
ASP A 777
SER A 779
VAL A 445
THR A 756
 None
 1.32A 5y80A-5m2nA:
undetectable		 5y80A-5m2nA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 758
SER A 721
LEU A 731
ILE A 755
PRO A 751
 None
 1.34A 6dlzB-5m2nA:
undetectable
6dlzC-5m2nA:
undetectable		 6dlzB-5m2nA:
9.00
6dlzC-5m2nA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 755
PRO A 751
LEU A 758
SER A 721
LEU A 731
 None
 1.33A 6dlzA-5m2nA:
undetectable
6dlzD-5m2nA:
undetectable		 6dlzA-5m2nA:
9.00
6dlzD-5m2nA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 758
LEU A 731
ILE A 755
PRO A 751
GLY A 727
 None
 1.06A 6dm0B-5m2nA:
undetectable
6dm0C-5m2nA:
undetectable		 6dm0B-5m2nA:
9.00
6dm0C-5m2nA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 758
SER A 721
LEU A 731
ILE A 755
PRO A 751
 None
 1.34A 6dm1B-5m2nA:
undetectable
6dm1C-5m2nA:
undetectable		 6dm1B-5m2nA:
9.00
6dm1C-5m2nA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 755
PRO A 751
LEU A 758
SER A 721
LEU A 731
 None
 1.33A 6dm1A-5m2nA:
undetectable
6dm1D-5m2nA:
undetectable		 6dm1A-5m2nA:
9.00
6dm1D-5m2nA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 758
SER A 721
LEU A 731
ILE A 755
PRO A 751
 None
 1.35A 6dm2B-5m2nA:
undetectable
6dm2C-5m2nA:
undetectable		 6dm2B-5m2nA:
9.00
6dm2C-5m2nA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 755
PRO A 751
LEU A 758
SER A 721
LEU A 731
 None
 1.33A 6dm2A-5m2nA:
undetectable
6dm2D-5m2nA:
undetectable		 6dm2A-5m2nA:
9.00
6dm2D-5m2nA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 5m2n ELONGATOR COMPLEX
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  12
VAL A  51
ILE A  10
PHE A 412
PRO A 537
 None
 1.15A 6hlpA-5m2nA:
undetectable		 6hlpA-5m2nA:
20.88