SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m2y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 5m2y TSSK C
(Escherichia
coli) 		4 / 5 LEU A 334
GLU A 331
ALA A 421
LEU A 419
 None
 1.03A 1eta1-5m2yA:
undetectable		 1eta1-5m2yA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 5m2y TSSK C
(Escherichia
coli) 		4 / 5 LEU A 334
GLU A 331
ALA A 421
LEU A 419
 None
 1.06A 1eta2-5m2yA:
undetectable		 1eta2-5m2yA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 5m2y TSSK C
(Escherichia
coli) 		4 / 6 LEU A 334
GLU A 331
ALA A 421
LEU A 419
 None
 1.04A 1etb1-5m2yA:
undetectable		 1etb1-5m2yA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 5m2y TSSK C
(Escherichia
coli) 		4 / 6 LEU A 334
GLU A 331
ALA A 421
LEU A 419
 None
 1.07A 1etb2-5m2yA:
undetectable		 1etb2-5m2yA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5m2y TSSK C
(Escherichia
coli) 		5 / 12 PHE A 345
PHE A 426
GLY A 369
GLY A 332
LEU A 334
 None
 1.12A 1igxA-5m2yA:
undetectable		 1igxA-5m2yA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 5m2y TSSK C
(Escherichia
coli) 		4 / 6 LEU A 334
GLU A 331
ALA A 421
LEU A 419
 None
 1.18A 1sn5A-5m2yA:
undetectable		 1sn5A-5m2yA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5m2y TSSK C
(Escherichia
coli) 		5 / 12 LEU A 439
LEU A 339
LEU A 334
GLY A 422
PHE A 426
 None
 1.31A 3n58A-5m2yA:
undetectable		 3n58A-5m2yA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 5m2y TSSK C
(Escherichia
coli) 		4 / 6 LEU A 408
LEU A 410
LEU A 339
LEU A 419
 None
 1.05A 3q1eA-5m2yA:
undetectable
3q1eC-5m2yA:
undetectable		 3q1eA-5m2yA:
20.98
3q1eC-5m2yA:
20.98