SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 189
HIS A 260
ASP A  31
HIS A 292
GLY A  37
 None
 1.06A 1d4fB-5m30A:
undetectable		 1d4fB-5m30A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 189
HIS A 260
HIS A 292
LEU A  38
GLY A  37
 None
 1.30A 1d4fB-5m30A:
undetectable		 1d4fB-5m30A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 303
LEU A 306
ASN A 307
LEU A 309
LEU A 250
 None
 1.01A 1sqnA-5m30A:
undetectable		 1sqnA-5m30A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 303
LEU A 306
ASN A 307
LEU A 309
LEU A 250
 None
 1.15A 1sqnB-5m30A:
undetectable		 1sqnB-5m30A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 303
LEU A 306
ASN A 307
LEU A 309
LEU A 250
 None
 1.21A 1zucB-5m30A:
undetectable		 1zucB-5m30A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		4 / 7 LEU A  54
GLN A 177
LEU A  59
PHE A  49
 None
 0.95A 2dysP-5m30A:
5.4
2dysW-5m30A:
undetectable		 2dysP-5m30A:
17.82
2dysW-5m30A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 303
LEU A 306
ASN A 307
LEU A 309
LEU A 250
 None
 1.02A 2w8yB-5m30A:
undetectable		 2w8yB-5m30A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		4 / 6 PHE A  68
LEU A 152
VAL A 100
VAL A  44
 None
 1.16A 2zawA-5m30A:
undetectable		 2zawA-5m30A:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		4 / 7 LEU A  54
GLN A 177
LEU A  59
PHE A  49
 None
 1.00A 3ag2P-5m30A:
2.1
3ag2W-5m30A:
undetectable		 3ag2P-5m30A:
17.82
3ag2W-5m30A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 303
LEU A 306
ASN A 307
LEU A 309
LEU A 250
 None
 1.06A 3d90A-5m30A:
undetectable		 3d90A-5m30A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 275
LEU A 310
LEU A 208
LEU A 268
LEU A 254
 None
 1.11A 3r9cA-5m30A:
undetectable		 3r9cA-5m30A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		4 / 7 LEU A  54
GLN A 177
LEU A  59
PHE A  49
 None
 0.94A 3x2qP-5m30A:
5.4
3x2qW-5m30A:
undetectable		 3x2qP-5m30A:
17.82
3x2qW-5m30A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		3 / 3 GLN A 157
HIS A 156
ARG A  94
 None
 0.95A 4qyqA-5m30A:
undetectable		 4qyqA-5m30A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		3 / 3 GLN A 157
HIS A 156
ARG A  94
 None
 0.98A 4qyqB-5m30A:
undetectable		 4qyqB-5m30A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		4 / 6 LEU A  54
PRO A 182
PHE A 184
GLU A 296
 None
 0.83A 5b8iA-5m30A:
undetectable		 5b8iA-5m30A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 189
HIS A 260
ASP A  31
HIS A 292
GLY A  37
 None
 1.01A 5hm8F-5m30A:
undetectable		 5hm8F-5m30A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 189
HIS A 260
HIS A 292
LEU A  38
GLY A  37
 None
 1.37A 5hm8F-5m30A:
undetectable		 5hm8F-5m30A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 5m30 TYPE VI SECRETION
PROTEIN
(Escherichia
coli) 		3 / 3 LYS A 145
TRP A 125
SER A 127
 None
 1.37A 5nwwA-5m30A:
undetectable		 5nwwA-5m30A:
6.20