SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m31'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_B_FUAB703_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	5m31	APPR-1-P PROCESSING DOMAIN PROTEIN (Thermus aquaticus)	5 / 12	PHE A 75 LEU A 113 VAL A 144 VAL A 18 THR A 20	None	1.23A	1q23B-5m31A: undetectable	1q23B-5m31A: 18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEI_A_CXXA801_1 (TRANSPORTER)	5m31	APPR-1-P PROCESSING DOMAIN PROTEIN (Thermus aquaticus)	5 / 11	LEU A 96 LEU A 99 GLN A 104 ILE A 132 LEU A 2	None	1.23A	2qeiA-5m31A: undetectable	2qeiA-5m31A: 13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WBO_B_ANWB601_0 (RHODOPSIN KINASE)	5m31	APPR-1-P PROCESSING DOMAIN PROTEIN (Thermus aquaticus)	4 / 8	LEU A 10 ALA A 38 ASN A 19 ALA A 112	CL A 204 ( 4.8A) None None None	0.77A	4wboB-5m31A: undetectable	4wboB-5m31A: 16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	5m31	APPR-1-P PROCESSING DOMAIN PROTEIN (Thermus aquaticus)	4 / 7	ASN A 19 GLY A 95 VAL A 144 LEU A 113	None	0.83A	6dwnB-5m31A: undetectable	6dwnB-5m31A: 23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNE_A_ACRA602_1 (-)	5m31	APPR-1-P PROCESSING DOMAIN PROTEIN (Thermus aquaticus)	5 / 12	GLY A 121 GLY A 122 VAL A 128 PRO A 115 GLY A 117	None	1.16A	6gneA-5m31A: 3.1	6gneA-5m31A: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNE_B_ACRB602_1 (-)	5m31	APPR-1-P PROCESSING DOMAIN PROTEIN (Thermus aquaticus)	5 / 12	GLY A 121 GLY A 122 VAL A 128 PRO A 115 GLY A 117	None	1.16A	6gneB-5m31A: 3.2	6gneB-5m31A: 15.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Q23_B_FUAB703_1","CHLORAMPHENICOL ACETYLTRANSFERASE","5m31","APPR-1-P PROCESSING DOMAIN PROTEIN","Thermus aquaticus",5,"PHE A  75;LEU A 113;VAL A 144;VAL A  18;THR A  20","None","1.23A","1q23B-5m31A:undetectable","1q23B-5m31A:18.47"],["2QEI_A_CXXA801_1","TRANSPORTER","5m31","APPR-1-P PROCESSING DOMAIN PROTEIN","Thermus aquaticus",5,"LEU A  96;LEU A  99;GLN A 104;ILE A 132;LEU A   2","None","1.23A","2qeiA-5m31A:undetectable","2qeiA-5m31A:13.62"],["4WBO_B_ANWB601_0","RHODOPSIN KINASE","5m31","APPR-1-P PROCESSING DOMAIN PROTEIN","Thermus aquaticus",4,"LEU A  10;ALA A  38;ASN A  19;ALA A 112"," CL A 204 ( 4.8A);None;None;None","0.77A","4wboB-5m31A:undetectable","4wboB-5m31A:16.47"],["6DWN_B_AQ4B602_1","CYTOCHROME P450 1A1","5m31","APPR-1-P PROCESSING DOMAIN PROTEIN","Thermus aquaticus",4,"ASN A  19;GLY A  95;VAL A 144;LEU A 113","None","0.83A","6dwnB-5m31A:undetectable","6dwnB-5m31A:23.13"],["6GNE_A_ACRA602_1","-","5m31","APPR-1-P PROCESSING DOMAIN PROTEIN","Thermus aquaticus",5,"GLY A 121;GLY A 122;VAL A 128;PRO A 115;GLY A 117","None","1.16A","6gneA-5m31A:3.1","6gneA-5m31A:15.58"],["6GNE_B_ACRB602_1","-","5m31","APPR-1-P PROCESSING DOMAIN PROTEIN","Thermus aquaticus",5,"GLY A 121;GLY A 122;VAL A 128;PRO A 115;GLY A 117","None","1.16A","6gneB-5m31A:3.2","6gneB-5m31A:15.58"]]