SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m38'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5m38 OMPA FAMILY PROTEIN
(Escherichia
coli) 		5 / 10 LEU A  30
ALA A  29
ILE A  33
VAL A  67
ALA A  64
 None
 1.17A 1xp0A-5m38A:
undetectable		 1xp0A-5m38A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5m38 OMPA FAMILY PROTEIN
(Escherichia
coli) 		4 / 5 SER A 111
VAL A   3
SER A  44
VAL A  42
 None
 1.12A 2j9cA-5m38A:
undetectable
2j9cB-5m38A:
undetectable
2j9cC-5m38A:
undetectable		 2j9cA-5m38A:
undetectable
2j9cB-5m38A:
undetectable
2j9cC-5m38A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5m38 OMPA FAMILY PROTEIN
(Escherichia
coli) 		3 / 3 SER A  80
LEU A  30
MET A  71
 None
 0.79A 5ikrB-5m38A:
undetectable		 5ikrB-5m38A:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 5m38 OMPA FAMILY PROTEIN
(Escherichia
coli) 		3 / 3 PHE A  11
ASP A  12
LYS A  19
 None
 0.88A 6awtD-5m38A:
undetectable		 6awtD-5m38A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWV_A_BEZA202_0
(ARA H 8 ALLERGEN)		 5m38 OMPA FAMILY PROTEIN
(Escherichia
coli) 		4 / 4 PHE A  11
ASP A  12
LEU A  18
LYS A  19
 None
 1.26A 6awvA-5m38A:
undetectable		 6awvA-5m38A:
undetectable