SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m3h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		4 / 6 ILE A  54
ARG A  75
TYR A 112
PHE A  76
 None
 1.33A 1e73M-5m3hA:
undetectable		 1e73M-5m3hA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		4 / 6 LEU A 341
TRP A 338
LEU A 558
PHE A 520
 None
 1.36A 1ru9H-5m3hA:
undetectable
1ru9L-5m3hA:
undetectable		 1ru9H-5m3hA:
13.83
1ru9L-5m3hA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		4 / 6 LEU A 341
TRP A 338
LEU A 558
PHE A 520
 None
 1.42A 1rukH-5m3hA:
undetectable
1rukL-5m3hA:
undetectable		 1rukH-5m3hA:
13.83
1rukL-5m3hA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		3 / 3 TYR A 453
GLU A 405
THR A 523
 None
 1.02A 2y7hB-5m3hA:
undetectable		 2y7hB-5m3hA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		5 / 12 GLY A 626
ARG A 610
VAL A 631
ILE A 628
GLU A 444
 None
 1.47A 3jb2A-5m3hA:
undetectable		 3jb2A-5m3hA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		4 / 6 CYH A  95
THR A  98
ASN A 100
ILE A  90
 None
 1.43A 3w9tB-5m3hA:
undetectable		 3w9tB-5m3hA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		4 / 7 GLY A 564
VAL A 512
ASN A 563
GLY A 366
 U  V   3 ( 3.6A)
C  V   9 ( 3.9A)
U  V   3 ( 4.2A)
A  V   1 ( 3.0A)
 0.85A 4forA-5m3hA:
undetectable		 4forA-5m3hA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		5 / 12 LEU A 341
LEU A 342
LEU A 558
ILE A 500
ILE A 516
 None
 0.96A 4j24A-5m3hA:
undetectable		 4j24A-5m3hA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		4 / 5 GLY A 674
SER A 259
PHE A 676
GLU A 258
 None
 1.04A 4m93B-5m3hA:
undetectable
4m93C-5m3hA:
undetectable		 4m93B-5m3hA:
13.24
4m93C-5m3hA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		5 / 11 LEU A 580
SER A 451
SER A 639
LEU A 581
LEU A 636
 None
 1.48A 4or0A-5m3hA:
undetectable		 4or0A-5m3hA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		5 / 12 ILE A 499
GLU A 519
GLY A 497
MET A 304
LEU A 341
 None
 1.34A 5fhzD-5m3hA:
undetectable		 5fhzD-5m3hA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		3 / 3 ASN A 115
TYR A 110
CYH A  95
 None
 1.05A 5lsuB-5m3hA:
undetectable		 5lsuB-5m3hA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5m3h POLYMERASE ACIDIC
PROTEIN
(Influenza
A
virus) 		3 / 3 GLN A 212
TYR A 226
ASN A 216
 None
 1.07A 6dwdC-5m3hA:
undetectable		 6dwdC-5m3hA:
21.71