SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m41'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 5 SER A 479
PHE A 589
GLU A 477
GLY A 475
 None
 1.23A 1icrA-5m41A:
undetectable
1icrB-5m41A:
undetectable		 1icrA-5m41A:
19.02
1icrB-5m41A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 5 GLU A 477
GLY A 475
SER A 479
PHE A 589
 None
 1.22A 1icrA-5m41A:
undetectable
1icrB-5m41A:
undetectable		 1icrA-5m41A:
19.02
1icrB-5m41A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_A_NIOA704_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 4 SER A 479
PHE A 589
GLU A 477
GLY A 475
 None
 1.21A 1icvA-5m41A:
undetectable
1icvB-5m41A:
undetectable		 1icvA-5m41A:
19.02
1icvB-5m41A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 5 SER A 479
PHE A 589
GLU A 477
GLY A 475
 None
 1.23A 1icvC-5m41A:
undetectable
1icvD-5m41A:
undetectable		 1icvC-5m41A:
19.02
1icvD-5m41A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 5 GLU A 477
GLY A 475
SER A 479
PHE A 589
 None
 1.20A 1icvC-5m41A:
undetectable
1icvD-5m41A:
undetectable		 1icvC-5m41A:
19.02
1icvD-5m41A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 GLY A 480
ALA A 471
MET A 481
GLY A 567
HIS A 587
 None
 1.03A 1kiaA-5m41A:
undetectable		 1kiaA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 GLY A 480
ALA A 471
MET A 481
GLY A 567
HIS A 587
 None
 1.03A 1kiaB-5m41A:
undetectable		 1kiaB-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 GLY A 480
ALA A 471
MET A 481
GLY A 567
HIS A 587
 None
 1.03A 1kiaC-5m41A:
undetectable		 1kiaC-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 5 GLU A 477
GLY A 475
SER A 479
PHE A 589
 None
 1.25A 1kqbA-5m41A:
undetectable
1kqbB-5m41A:
undetectable		 1kqbA-5m41A:
undetectable
1kqbB-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 GLY A 480
ALA A 471
MET A 481
GLY A 567
HIS A 587
 None
 1.03A 1nbhB-5m41A:
undetectable		 1nbhB-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 6 VAL A 262
THR A 265
GLU A  35
LEU A  32
 None
 1.03A 1s8fB-5m41A:
undetectable		 1s8fB-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 LEU A 739
LEU A 742
ALA A 746
MET A 722
THR A 663
 None
 1.01A 1ya3C-5m41A:
undetectable		 1ya3C-5m41A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 LEU A 103
VAL A 206
VAL A 182
LEU A  32
LEU A 199
 None
 1.17A 2hc4A-5m41A:
undetectable		 2hc4A-5m41A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 11 SER A 372
LEU A 244
ILE A  20
GLY A  19
GLY A  18
SER A 252
 None
 1.39A 2qmmA-5m41A:
undetectable
2qmmB-5m41A:
undetectable		 2qmmA-5m41A:
undetectable
2qmmB-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 LEU A 730
VAL A 729
THR A 672
SER A 708
PHE A 651
 None
 1.44A 2y00B-5m41A:
undetectable		 2y00B-5m41A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 LEU A 730
VAL A 729
THR A 672
SER A 708
PHE A 651
 None
 1.43A 2y01B-5m41A:
undetectable		 2y01B-5m41A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 LEU A 103
VAL A 206
VAL A 182
LEU A  32
LEU A 199
 None
 1.21A 2zlcA-5m41A:
undetectable		 2zlcA-5m41A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 ALA A  44
GLY A 213
LEU A  49
SER A  50
LEU A 177
 None
 1.30A 3bxoA-5m41A:
undetectable		 3bxoA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 11 LEU A 230
ALA A 263
LEU A 261
ASN A  39
ALA A 214
 None
 1.30A 3e22B-5m41A:
undetectable		 3e22B-5m41A:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 7 GLN A 728
LEU A 742
VAL A 674
LEU A 601
 None
 0.92A 3g8iA-5m41A:
undetectable		 3g8iA-5m41A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 6 ASN A 491
LEU A 566
ASP A 565
LYS A 570
 None
 1.38A 3lslG-5m41A:
undetectable		 3lslG-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.50A 3p97A-5m41A:
undetectable		 3p97A-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 11 ASP A 687
PHE A 689
ASN A 578
SER A 697
LEU A 554
 None
 1.32A 3qg2B-5m41A:
undetectable		 3qg2B-5m41A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 8 ALA A 334
GLY A 366
THR A 365
THR A 440
 None
 0.94A 3rglA-5m41A:
undetectable		 3rglA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		3 / 3 ASN A 417
ALA A 420
LYS A 414
 None
 1.00A 3runA-5m41A:
undetectable		 3runA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 5 TYR A  64
SER A  50
GLY A 213
ARG A 216
 None
 1.46A 3v4tA-5m41A:
undetectable
3v4tD-5m41A:
undetectable		 3v4tA-5m41A:
undetectable
3v4tD-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 7 ASP A 138
PHE A 131
GLY A  82
PHE A 164
 None
 1.02A 3vnsA-5m41A:
undetectable		 3vnsA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 5 HIS A 431
GLY A 353
TYR A 428
GLU A 434
 None
 1.40A 4ae1B-5m41A:
undetectable		 4ae1B-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 ASP A 368
PHE A 446
GLN A 292
VAL A 342
ILE A 341
ILE A 389
 None
 1.34A 4drhA-5m41A:
undetectable		 4drhA-5m41A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 ASP A 368
PHE A 446
GLN A 292
VAL A 342
ILE A 341
 None
 1.01A 4drhD-5m41A:
undetectable		 4drhD-5m41A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 PHE A 446
GLN A 292
VAL A 342
ILE A 341
ILE A 389
 None
 1.20A 4drhD-5m41A:
undetectable		 4drhD-5m41A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 LEU A 739
LEU A 742
ALA A 746
MET A 722
THR A 663
 None
 1.16A 4fn9B-5m41A:
undetectable		 4fn9B-5m41A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 GLY A  82
GLU A 135
TYR A  41
ASN A 104
ASN A 102
 None
 1.29A 4pb1A-5m41A:
undetectable		 4pb1A-5m41A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 11 GLY A 383
ILE A 307
GLY A 416
ILE A 388
PHE A 251
 None
 1.13A 4qoiA-5m41A:
undetectable
4qoiB-5m41A:
undetectable		 4qoiA-5m41A:
18.47
4qoiB-5m41A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 6 ALA A 255
ILE A 438
GLY A 359
ILE A 247
VAL A 328
 None
 1.01A 4r21A-5m41A:
undetectable		 4r21A-5m41A:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 9 ALA A 255
ILE A 438
GLY A 359
ILE A 247
VAL A 328
 None
 1.00A 4r21B-5m41A:
undetectable		 4r21B-5m41A:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 ALA A 575
ILE A 574
ASN A 489
MET A 481
GLY A 480
 None
 0.99A 4r38C-5m41A:
undetectable		 4r38C-5m41A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_A_RPBA1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 11 GLN A 279
HIS A 431
GLY A 353
TYR A 428
GLU A 434
 None
 1.25A 4rv6A-5m41A:
undetectable		 4rv6A-5m41A:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_B_RPBB1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 11 GLN A 279
HIS A 431
GLY A 353
TYR A 428
GLU A 434
 None
 1.26A 4rv6B-5m41A:
undetectable		 4rv6B-5m41A:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.49A 5e9qA-5m41A:
undetectable		 5e9qA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.48A 5ec8A-5m41A:
undetectable		 5ec8A-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 PRO A 579
GLY A 338
ASP A 687
LEU A 629
TYR A 580
 None
 1.40A 5eeiA-5m41A:
undetectable		 5eeiA-5m41A:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 12 PRO A 579
GLY A 338
ASP A 687
LEU A 629
TYR A 580
 None
 1.41A 5eeiB-5m41A:
undetectable		 5eeiB-5m41A:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 6 GLY A 339
ILE A 499
TYR A 498
TYR A 545
 None
 1.14A 5iwuA-5m41A:
undetectable		 5iwuA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 6 GLY A 433
ASP A 196
ILE A 247
ARG A  28
 None
 1.01A 5iwuA-5m41A:
undetectable		 5iwuA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		3 / 3 GLY A 416
ASP A 387
ASN A 384
 None
 0.39A 5jglA-5m41A:
undetectable		 5jglA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 7 LEU A 691
ILE A 649
MET A 722
MET A 698
 None
 1.38A 5ljcA-5m41A:
undetectable		 5ljcA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.49A 5wz1A-5m41A:
undetectable		 5wz1A-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.46A 5wz1B-5m41A:
undetectable		 5wz1B-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.48A 5wz1C-5m41A:
undetectable		 5wz1C-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.48A 5wz1D-5m41A:
undetectable		 5wz1D-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.49A 5wz1E-5m41A:
undetectable		 5wz1E-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.47A 5wz1F-5m41A:
undetectable		 5wz1F-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.48A 5wz1G-5m41A:
undetectable		 5wz1G-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.49A 5wz1H-5m41A:
undetectable		 5wz1H-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		6 / 12 GLY A 612
GLY A 623
TRP A 628
THR A 615
VAL A 684
ILE A 610
 None
 1.50A 5wz2B-5m41A:
undetectable		 5wz2B-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA814_0
(UNCHARACTERIZED
PROTEIN)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		4 / 5 GLN A 129
ASN A 104
THR A 201
LEU A 204
 None
 1.21A 6d8pA-5m41A:
undetectable		 6d8pA-5m41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5m41 NIGRITOXINE
(Vibrio
nigripulchritudo) 		5 / 10 ASP A 558
GLY A 338
SER A 399
ALA A 396
ASN A 693
 None
 1.46A 6hu9L-5m41A:
undetectable
6hu9P-5m41A:
undetectable
6hu9T-5m41A:
undetectable		 6hu9L-5m41A:
undetectable
6hu9P-5m41A:
undetectable
6hu9T-5m41A:
undetectable