SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m43'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4G_B_ZMRB466_2 (NEURAMINIDASE)	5m43	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	3 / 3	ASP A 60 ARG A 109 ILE A 38	None NO3 A 301 (-3.9A) None	0.84A	1a4gB-5m43A: undetectable	1a4gB-5m43A: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N49_A_SAMA601_0 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	5m43	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	GLY A 97 PRO A 96 GLY A 84 THR A 32 ILE A 34	None	1.01A	4n49A-5m43A: undetectable	4n49A-5m43A: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_A_RTLA201_0 (RETINOL-BINDING PROTEIN 2)	5m43	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	ALA A 153 VAL A 75 LEU A 118 TRP A 166 LEU A 163	None	1.40A	4qzuA-5m43A: undetectable	4qzuA-5m43A: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_B_ACTB310_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	5m43	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	4 / 4	GLY A 154 PRO A 155 VAL A 111 ARG A 147	None	1.12A	5uunA-5m43A: undetectable 5uunB-5m43A: undetectable	5uunA-5m43A: 21.57 5uunB-5m43A: 21.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A4G_B_ZMRB466_2","NEURAMINIDASE","5m43","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",3,"ASP A  60;ARG A 109;ILE A  38","None;NO3 A 301 (-3.9A);None","0.84A","1a4gB-5m43A:undetectable","1a4gB-5m43A:19.95"],["4N49_A_SAMA601_0","CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1","5m43","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"GLY A  97;PRO A  96;GLY A  84;THR A  32;ILE A  34","None","1.01A","4n49A-5m43A:undetectable","4n49A-5m43A:18.60"],["4QZU_A_RTLA201_0","RETINOL-BINDING PROTEIN 2","5m43","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"ALA A 153;VAL A  75;LEU A 118;TRP A 166;LEU A 163","None","1.40A","4qzuA-5m43A:undetectable","4qzuA-5m43A:18.97"],["5UUN_B_ACTB310_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","5m43","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",4,"GLY A 154;PRO A 155;VAL A 111;ARG A 147","None","1.12A","5uunA-5m43A:undetectable;5uunB-5m43A:undetectable","5uunA-5m43A:21.57;5uunB-5m43A:21.57"]]