SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m45'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 8 GLY B 285
GLY B 311
SER B 314
GLY B  20
 None
AMP  B 801 (-3.5A)
None
AMP  B 801 ( 3.7A)
 0.75A 1d0vA-5m45B:
1.7		 1d0vA-5m45B:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 8 GLY B 285
GLY B 311
SER B 314
GLY B  20
 None
AMP  B 801 (-3.5A)
None
AMP  B 801 ( 3.7A)
 0.72A 1jhaA-5m45B:
undetectable		 1jhaA-5m45B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 10 ALA B 318
VAL B 343
ILE B 287
GLY B 288
GLY B 289
 None
 1.05A 1k6cA-5m45B:
undetectable		 1k6cA-5m45B:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 10 LEU B 319
VAL B 343
ILE B 287
GLY B 288
GLY B 289
 None
 0.94A 1k6cA-5m45B:
undetectable		 1k6cA-5m45B:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 11 ALA B 507
GLY B 499
GLY B 292
ILE B 291
TYR B 471
 None
 1.09A 1pg2A-5m45B:
undetectable		 1pg2A-5m45B:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 7 GLY B 143
ARG B 138
ILE B  97
VAL B  98
 None
 0.87A 1rxcC-5m45B:
2.3		 1rxcC-5m45B:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 7 SER B 314
ASP B 316
SER B 470
LEU B 448
 None
 0.89A 2cdqB-5m45B:
undetectable		 2cdqB-5m45B:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 5 PRO B 286
ILE B 287
GLY B 289
TYR B 471
 None
 1.04A 2jkjD-5m45B:
undetectable		 2jkjD-5m45B:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 5 PRO B 286
ILE B 287
GLY B 289
TYR B 471
 None
 1.04A 2jkjF-5m45B:
undetectable		 2jkjF-5m45B:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 8 HIS B 267
TYR B 219
ARG B 280
THR B 230
 None
 1.28A 2vxaF-5m45B:
2.9
2vxaG-5m45B:
2.9
2vxaI-5m45B:
3.1		 2vxaF-5m45B:
7.26
2vxaG-5m45B:
7.26
2vxaI-5m45B:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 5 ALA B 237
GLY B 177
CYH B  94
LYS B  93
 None
 1.27A 2ylgA-5m45B:
undetectable		 2ylgA-5m45B:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 LEU B  14
GLY B  75
ASP B 260
LEU B  72
LEU B  69
 None
 1.10A 2zbpA-5m45B:
undetectable		 2zbpA-5m45B:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 7 ALA B 350
ILE B 390
ILE B 310
HIS B 394
 None
 0.95A 2zm7A-5m45B:
undetectable		 2zm7A-5m45B:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 8 SER B 284
ALA B  18
THR B 244
ILE B 248
 None
 0.86A 3bpxA-5m45B:
0.7
3bpxB-5m45B:
undetectable		 3bpxA-5m45B:
12.86
3bpxB-5m45B:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 LEU B 340
LEU B 338
GLN B 113
LEU B 135
TYR B 219
 None
 1.11A 3d90B-5m45B:
undetectable		 3d90B-5m45B:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 9 ARG B 570
ILE B 287
GLY B 269
PRO B 341
ILE B 327
 None
 1.29A 3ekyB-5m45B:
undetectable		 3ekyB-5m45B:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 4 ARG B 375
ASP B  24
GLY B 473
THR B 313
 None
MG  B 802 (-3.0A)
AMP  B 801 (-3.3A)
None
 1.33A 3k4vB-5m45B:
undetectable		 3k4vB-5m45B:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 ALA B 502
ASP B  17
ASP B  24
VAL B  28
ALA B 508
 None
MG  B 802 ( 4.8A)
MG  B 802 (-3.0A)
None
None
 1.18A 3n3iA-5m45B:
undetectable		 3n3iA-5m45B:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 ASP B 309
ASP B 316
GLY B 288
ILE B 291
ILE B 287
 MG  B 803 (-2.2A)
None
None
None
None
 1.20A 3n3iA-5m45B:
undetectable		 3n3iA-5m45B:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		3 / 3 HIS B 184
SER B 215
ASN B  99
 None
 0.90A 3s8pB-5m45B:
undetectable		 3s8pB-5m45B:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 7 ALA B 502
ASP B  17
ASP B  24
VAL B  36
 None
MG  B 802 ( 4.8A)
MG  B 802 (-3.0A)
None
 0.70A 3t3cA-5m45B:
undetectable		 3t3cA-5m45B:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 9 ALA B 508
ASP B 509
GLY B 268
ILE B 287
VAL B  76
 None
 0.96A 3u7sA-5m45B:
undetectable		 3u7sA-5m45B:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 6 ASP B 515
ASN B 329
ASP B 579
GLU B 581
 None
 1.32A 4gkhJ-5m45B:
undetectable		 4gkhJ-5m45B:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 5 GLN B  40
THR B  21
THR B 695
LEU B 412
 None
AMP  B 801 (-4.0A)
AMP  B 801 (-3.8A)
None
 0.87A 4lvcB-5m45B:
undetectable		 4lvcB-5m45B:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 GLY B 351
THR B  21
LEU B 367
ASP B 447
ILE B 310
 None
AMP  B 801 (-4.0A)
None
MG  B 806 (-3.5A)
None
 1.41A 4pghB-5m45B:
undetectable		 4pghB-5m45B:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 11 THR B 694
GLY B 311
GLY B 312
ALA B 352
SER B 391
 None
AMP  B 801 (-3.5A)
AMP  B 801 (-3.6A)
AMP  B 801 (-3.2A)
AMP  B 801 ( 4.5A)
 1.02A 4qvlK-5m45B:
undetectable
4qvlL-5m45B:
undetectable		 4qvlK-5m45B:
16.17
4qvlL-5m45B:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 11 THR B 694
GLY B 311
GLY B 312
ALA B 352
SER B 391
 None
AMP  B 801 (-3.5A)
AMP  B 801 (-3.6A)
AMP  B 801 (-3.2A)
AMP  B 801 ( 4.5A)
 1.02A 4qvlY-5m45B:
undetectable
4qvlZ-5m45B:
undetectable		 4qvlY-5m45B:
16.17
4qvlZ-5m45B:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 10 THR B 694
GLY B 311
GLY B 312
ALA B 352
SER B 391
 None
AMP  B 801 (-3.5A)
AMP  B 801 (-3.6A)
AMP  B 801 (-3.2A)
AMP  B 801 ( 4.5A)
 1.02A 4qvmY-5m45B:
undetectable
4qvmZ-5m45B:
undetectable		 4qvmY-5m45B:
16.17
4qvmZ-5m45B:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		6 / 12 GLY B 353
GLY B 351
GLY B 311
SER B 354
THR B 387
ALA B 372
 None
None
AMP  B 801 (-3.5A)
None
None
None
 1.40A 4uckA-5m45B:
undetectable		 4uckA-5m45B:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 ALA B 372
LEU B 448
HIS B 478
ALA B 352
GLY B 475
 None
None
None
AMP  B 801 (-3.2A)
None
 0.82A 4v04B-5m45B:
undetectable		 4v04B-5m45B:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 11 THR B 694
GLY B 311
GLY B 312
ALA B 352
SER B 391
 None
AMP  B 801 (-3.5A)
AMP  B 801 (-3.6A)
AMP  B 801 (-3.2A)
AMP  B 801 ( 4.5A)
 1.00A 5bxnK-5m45B:
undetectable
5bxnL-5m45B:
undetectable		 5bxnK-5m45B:
16.17
5bxnL-5m45B:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 11 THR B 694
GLY B 311
GLY B 312
ALA B 352
SER B 391
 None
AMP  B 801 (-3.5A)
AMP  B 801 (-3.6A)
AMP  B 801 (-3.2A)
AMP  B 801 ( 4.5A)
 1.01A 5bxnY-5m45B:
undetectable
5bxnZ-5m45B:
undetectable		 5bxnY-5m45B:
16.17
5bxnZ-5m45B:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		3 / 3 HIS B 184
SER B 215
ASN B  99
 None
 0.88A 5cprB-5m45B:
undetectable		 5cprB-5m45B:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 7 PHE B 466
ILE B 456
GLY B 487
PHE B 488
 None
 0.77A 5h3aB-5m45B:
undetectable		 5h3aB-5m45B:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 ALA B 293
PRO B 494
THR B 694
PHE B 500
GLY B 472
 None
None
None
None
MG  B 803 ( 4.3A)
 1.33A 5hfjC-5m45B:
undetectable		 5hfjC-5m45B:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 PHE B 503
TYR B 295
LEU B 300
LEU B 711
PHE B  34
 None
 1.31A 5ieoA-5m45B:
undetectable		 5ieoA-5m45B:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 5 ALA B 237
GLY B 177
CYH B  94
LYS B  93
 None
 1.32A 5jliA-5m45B:
undetectable		 5jliA-5m45B:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 5 ALA B 237
GLY B 177
CYH B  94
LYS B  93
 None
 1.43A 5jt4A-5m45B:
undetectable		 5jt4A-5m45B:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 12 GLY B  79
GLY B 288
VAL B 263
ALA B 293
ASP B 309
 None
None
None
None
MG  B 803 (-2.2A)
 1.25A 5x7fA-5m45B:
undetectable		 5x7fA-5m45B:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		5 / 10 GLY B 268
GLY B 269
ILE B 287
ALA B 265
GLY B 288
 None
 1.12A 6e5zA-5m45B:
undetectable		 6e5zA-5m45B:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		3 / 3 PHE B  34
ARG B 710
ALA B 497
 None
 0.95A 6ecfB-5m45B:
4.4		 6ecfB-5m45B:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 8 ASN B 229
PHE B 105
VAL B 179
SER B 215
 None
 1.25A 6huoC-5m45B:
undetectable
6huoD-5m45B:
undetectable		 6huoC-5m45B:
7.92
6huoD-5m45B:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 5m45 ACETONE CARBOXYLASE
BETA SUBUNIT
(Xanthobacter
autotrophicus) 		4 / 8 LEU B  96
GLY B  95
LEU B 170
GLU B 103
 None
 0.78A 6mdqA-5m45B:
undetectable		 6mdqA-5m45B:
9.90