SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m4y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 5m4y EXOCYST COMPLEX
COMPONENT SEC3
(Saccharomyces
cerevisiae) 		3 / 3 TYR B 108
ARG B 113
GLN B  81
 None
 0.99A 1tw4A-5m4yB:
undetectable		 1tw4A-5m4yB:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5m4y EXOCYST COMPLEX
COMPONENT SEC3
(Saccharomyces
cerevisiae) 		5 / 12 GLU B 103
ASN B 146
LEU B 150
ILE B 151
LEU B 141
 None
 1.32A 4k36B-5m4yB:
undetectable		 4k36B-5m4yB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 5m4y EXOCYST COMPLEX
COMPONENT SEC3
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 172
ILE B 153
LEU B 139
GLU B 116
LYS B 155
 None
 1.06A 4y0rA-5m4yB:
undetectable		 4y0rA-5m4yB:
19.92