SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m50'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5m50 CALMODULIN-REGULATED
SPECTRIN-ASSOCIATED
PROTEIN 3
(Mus
musculus) 		5 / 12 LEU C1137
LEU C1132
ALA C1131
LEU C1175
CYH C1170
 None
 1.41A 2aa6A-5m50C:
undetectable		 2aa6A-5m50C:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 5m50 CALMODULIN-REGULATED
SPECTRIN-ASSOCIATED
PROTEIN 3
(Mus
musculus) 		4 / 5 SER C1225
VAL C1226
LYS C1206
PRO C1218
 None
 1.10A 6fi4A-5m50C:
undetectable
6fi4B-5m50C:
undetectable		 6fi4A-5m50C:
18.92
6fi4B-5m50C:
3.61