SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m5e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		4 / 4 LEU C  35
PRO C  36
LEU C  63
ARG C 114
 None
 1.16A 2qd2A-5m5eC:
undetectable		 2qd2A-5m5eC:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 5m5e INTERLEUKIN-2
(Homo
sapiens) 		4 / 7 ILE D  86
ILE D  24
LEU D  17
VAL D  93
 None
 0.80A 3ua5B-5m5eD:
undetectable		 3ua5B-5m5eD:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 GLN C  94
THR C  51
ASN C  49
 NAG  C 303 (-4.0A)
None
NAG  C 303 (-1.9A)
 0.89A 3v4tE-5m5eC:
undetectable		 3v4tE-5m5eC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		5 / 12 LEU C 140
VAL C 165
TYR C 197
TYR C 167
PHE C 186
 None
 1.47A 5cymA-5m5eC:
undetectable		 5cymA-5m5eC:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.63A 5qgjA-5m5eC:
undetectable		 5qgjA-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.67A 5qgmA-5m5eC:
undetectable		 5qgmA-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.64A 5qgnA-5m5eC:
undetectable		 5qgnA-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.53A 5qgyA-5m5eC:
undetectable		 5qgyA-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.51A 5qgzA-5m5eC:
undetectable		 5qgzA-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.51A 5qh0A-5m5eC:
undetectable		 5qh0A-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.51A 5qh2A-5m5eC:
undetectable		 5qh2A-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.53A 5qh3A-5m5eC:
undetectable		 5qh3A-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.59A 5qh5A-5m5eC:
undetectable		 5qh5A-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.56A 5qh6A-5m5eC:
undetectable		 5qh6A-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.55A 5qh7A-5m5eC:
undetectable		 5qh7A-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.49A 5qhaA-5m5eC:
undetectable		 5qhaA-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		3 / 3 VAL C  42
VAL C 130
GLN C 127
 None
 0.53A 5qhhA-5m5eC:
undetectable		 5qhhA-5m5eC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5m5e INTERLEUKIN-2
(Homo
sapiens) 		4 / 5 ARG D  38
MET D  39
THR D  41
LEU D  40
 None
 1.08A 5w97J-5m5eD:
undetectable		 5w97J-5m5eD:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 5m5e CYTOKINE RECEPTOR
COMMON SUBUNIT GAMMA
(Homo
sapiens) 		5 / 12 LEU C 140
VAL C 165
TYR C 197
TYR C 167
PHE C 186
 None
 1.46A 6eliA-5m5eC:
undetectable		 6eliA-5m5eC:
20.22