SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m5x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I00_A_D16A315_1 (THYMIDYLATE SYNTHASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 9	ASP B 841 LEU B 845 GLY B 844 PHE B 825 TYR B 847	None	1.32A	1i00A-5m5xB: undetectable	1i00A-5m5xB: 12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I00_B_D16B409_1 (THYMIDYLATE SYNTHASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 9	ASP B 841 LEU B 845 GLY B 844 PHE B 825 TYR B 847	None	1.36A	1i00B-5m5xB: undetectable	1i00B-5m5xB: 12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S8F_A_BEZA1502_0 (RAS-RELATED PROTEIN RAB-9A)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 4	HIS B 251 ILE B 217 GLN B 235 PHE B 222	None	1.44A	1s8fA-5m5xB: 0.0 1s8fB-5m5xB: 0.0	1s8fA-5m5xB: 10.12 1s8fB-5m5xB: 10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A7Q_A_CFBA328_2 (DEOXYCYTIDINE KINASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 4	ILE B 907 ASP B 738 LEU B 733 ARG B 909	None	1.22A	2a7qA-5m5xB: undetectable	2a7qA-5m5xB: 11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J9D_A_ACTA1117_0 (HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	3 / 3	ASP B 442 ARG B 448 ARG B 444	None	0.71A	2j9dA-5m5xB: undetectable 2j9dC-5m5xB: undetectable	2j9dA-5m5xB: 7.90 2j9dC-5m5xB: 7.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2TSR_C_D16C509_1 (THYMIDYLATE SYNTHASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 10	ASP B 841 LEU B 845 GLY B 844 PHE B 825 TYR B 847	None	1.30A	2tsrC-5m5xB: undetectable	2tsrC-5m5xB: 13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2TSR_D_D16D609_1 (THYMIDYLATE SYNTHASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 9	ASP B 841 LEU B 845 GLY B 844 PHE B 825 TYR B 847	None	1.35A	2tsrD-5m5xB: undetectable	2tsrD-5m5xB: 13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VAV_F_CSCF1383_2 (ACETYL-COA--DEACETYL CEPHALOSPORIN C ACETYLTRANSFERASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	3 / 3	LEU B 404 MET B 205 MET B 461	None	0.72A	2vavF-5m5xB: undetectable	2vavF-5m5xB: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_B_SALB1305_1 (LYSR-TYPE REGULATORY PROTEIN)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 5	ARG B 379 PRO B 581 GLY B 580 TRP B 595	None	1.37A	2y7kB-5m5xB: undetectable	2y7kB-5m5xB: 10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7P_A_SALA1001_1 (LYSR-TYPE REGULATORY PROTEIN)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 6	ARG B 379 PRO B 581 GLY B 580 TRP B 595	None	1.48A	2y7pA-5m5xB: undetectable	2y7pA-5m5xB: 10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_D_2FAD500_2 (ADENOSYLHOMOCYSTEINA SE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 4	LEU B 744 GLN B 748 THR B 746 THR B 725	None	1.26A	2zj0D-5m5xB: undetectable	2zj0D-5m5xB: 16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LTW_A_HLZA300_1 (ARYLAMINE N-ACETYLTRANSFERASE NAT)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 6	PHE B 986 TYR B 995 VAL B 752 PHE B 996	None	1.27A	3ltwA-5m5xB: undetectable	3ltwA-5m5xB: 11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NK2_X_LDPX433_1 (6-HYDROXY-L-NICOTINE OXIDASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 7	MET B 762 LEU B 703 LEU B 38 PHE B 765	None	1.32A	3nk2X-5m5xB: undetectable	3nk2X-5m5xB: 15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UJ7_A_SAMA301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 12	ILE B1151 ILE B1153 ARG B1134 ASP B1137 ALA B1138	None	1.26A	3uj7A-5m5xB: undetectable	3uj7A-5m5xB: 12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_D_ACTD502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	3 / 3	GLY B 727 THR B 725 ASN B 767	None	0.70A	3v4tD-5m5xB: undetectable	3v4tD-5m5xB: 16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EB4_C_D16C402_1 (THYMIDYLATE SYNTHASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 9	ASP B 841 LEU B 845 GLY B 844 PHE B 825 TYR B 847	None	1.32A	4eb4C-5m5xB: undetectable	4eb4C-5m5xB: 13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EB4_D_D16D402_1 (THYMIDYLATE SYNTHASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 10	ASP B 841 LEU B 845 GLY B 844 PHE B 825 TYR B 847	None	1.37A	4eb4D-5m5xB: undetectable	4eb4D-5m5xB: 13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKB_A_198A1002_2 (ANDROGEN RECEPTOR)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 6	LEU B 61 ASN B 62 LEU B 137 VAL B 155	None	1.02A	4okbA-5m5xB: undetectable	4okbA-5m5xB: 12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PCU_A_SAMA603_0 (CYSTATHIONINE BETA-SYNTHASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 7	ASP B 946 PRO B 932 ILE B 949 ASP B 782	None	1.04A	4pcuA-5m5xB: undetectable	4pcuA-5m5xB: 18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YOA_A_017A100_1 (HIV-1 PROTEASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 6	ASN B 755 THR B 692 PRO B 693 THR B 694	None	0.95A	4yoaA-5m5xB: undetectable	4yoaA-5m5xB: 6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5H3A_B_D16B401_1 (ORF70)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 7	ASP B 841 LEU B 845 GLY B 844 PHE B 825 TYR B 847	None	1.30A	5h3aB-5m5xB: undetectable	5h3aB-5m5xB: 14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IFU_A_GBMA801_1 (PROLINE--TRNA LIGASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 12	TYR B 409 LEU B 413 ARG B 134 ILE B 457 GLY B 458	None	1.17A	5ifuA-5m5xB: undetectable	5ifuA-5m5xB: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IFU_B_GBMB801_1 (PROLINE--TRNA LIGASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	6 / 9	ILE B 412 TYR B 409 LEU B 413 ARG B 134 ILE B 457 GLY B 458	None	1.25A	5ifuB-5m5xB: undetectable	5ifuB-5m5xB: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGW_A_CTYA404_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 12	ILE B 104 GLY B 135 ILE B 412 TYR B 409 MET B 461	None	1.30A	5igwA-5m5xB: undetectable	5igwA-5m5xB: 13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IWU_A_ACTA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 6	VAL B1031 MET B 787 ILE B 947 ASP B 946	None	0.96A	5iwuA-5m5xB: undetectable	5iwuA-5m5xB: 13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MLM_A_STRA401_1 (-)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 12	MET B1013 ILE B1026 VAL B 775 ILE B 776 PRO B 945	None	1.36A	5mlmA-5m5xB: undetectable	5mlmA-5m5xB: 15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NOO_C_D16C402_1 (THYMIDYLATE SYNTHASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 6	ASP B 841 LEU B 845 GLY B 844 PHE B 825 TYR B 847	None	1.32A	5nooC-5m5xB: undetectable	5nooC-5m5xB: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NOO_C_D16C402_1 (THYMIDYLATE SYNTHASE)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	5 / 6	TYR B 861 ASP B 841 LEU B 840 GLY B 844 TYR B 847	None	1.45A	5nooC-5m5xB: undetectable	5nooC-5m5xB: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 4	VAL B 358 LEU B 359 LEU B 362 ASP B 369	None	1.45A	5xv7A-5m5xB: undetectable	5xv7A-5m5xB: 6.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 6	GLN B 480 PHE B 464 LEU B 465 PHE B 194	None	1.05A	5z84P-5m5xB: undetectable 5z84W-5m5xB: undetectable	5z84P-5m5xB: 12.22 5z84W-5m5xB: 4.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z85_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 6	GLN B 480 PHE B 464 LEU B 465 PHE B 194	None	1.06A	5z85P-5m5xB: undetectable 5z85W-5m5xB: undetectable	5z85P-5m5xB: 12.22 5z85W-5m5xB: 4.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 6	GLN B 480 PHE B 464 LEU B 465 PHE B 194	None	1.04A	5z86P-5m5xB: undetectable 5z86W-5m5xB: undetectable	5z86P-5m5xB: 12.22 5z86W-5m5xB: 4.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCP_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 6	GLN B 480 PHE B 464 LEU B 465 PHE B 194	None	1.05A	5zcpP-5m5xB: undetectable 5zcpW-5m5xB: undetectable	5zcpP-5m5xB: 12.22 5zcpW-5m5xB: 4.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_W_CHDW102_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5m5x	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (Saccharomyces cerevisiae)	4 / 5	TYR B 742 ARG B1037 MET B 726 THR B 725	None G R 18 ( 4.6A) None None	1.31A	6nknW-5m5xB: undetectable	6nknW-5m5xB: 4.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1I00_A_D16A315_1","THYMIDYLATE SYNTHASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"ASP B 841;LEU B 845;GLY B 844;PHE B 825;TYR B 847","None","1.32A","1i00A-5m5xB:undetectable","1i00A-5m5xB:12.64"],["1I00_B_D16B409_1","THYMIDYLATE SYNTHASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"ASP B 841;LEU B 845;GLY B 844;PHE B 825;TYR B 847","None","1.36A","1i00B-5m5xB:undetectable","1i00B-5m5xB:12.64"],["1S8F_A_BEZA1502_0","RAS-RELATED PROTEIN RAB-9A","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"HIS B 251;ILE B 217;GLN B 235;PHE B 222","None","1.44A","1s8fA-5m5xB:0.0;1s8fB-5m5xB:0.0","1s8fA-5m5xB:10.12;1s8fB-5m5xB:10.12"],["2A7Q_A_CFBA328_2","DEOXYCYTIDINE KINASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"ILE B 907;ASP B 738;LEU B 733;ARG B 909","None","1.22A","2a7qA-5m5xB:undetectable","2a7qA-5m5xB:11.94"],["2J9D_A_ACTA1117_0","HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",3,"ASP B 442;ARG B 448;ARG B 444","None","0.71A","2j9dA-5m5xB:undetectable;2j9dC-5m5xB:undetectable","2j9dA-5m5xB:7.90;2j9dC-5m5xB:7.90"],["2TSR_C_D16C509_1","THYMIDYLATE SYNTHASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"ASP B 841;LEU B 845;GLY B 844;PHE B 825;TYR B 847","None","1.30A","2tsrC-5m5xB:undetectable","2tsrC-5m5xB:13.63"],["2TSR_D_D16D609_1","THYMIDYLATE SYNTHASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"ASP B 841;LEU B 845;GLY B 844;PHE B 825;TYR B 847","None","1.35A","2tsrD-5m5xB:undetectable","2tsrD-5m5xB:13.63"],["2VAV_F_CSCF1383_2","ACETYL-COA--DEACETYLCEPHALOSPORIN C ACETYLTRANSFERASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",3,"LEU B 404;MET B 205;MET B 461","None","0.72A","2vavF-5m5xB:undetectable","2vavF-5m5xB:18.11"],["2Y7K_B_SALB1305_1","LYSR-TYPE REGULATORY PROTEIN","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"ARG B 379;PRO B 581;GLY B 580;TRP B 595","None","1.37A","2y7kB-5m5xB:undetectable","2y7kB-5m5xB:10.81"],["2Y7P_A_SALA1001_1","LYSR-TYPE REGULATORY PROTEIN","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"ARG B 379;PRO B 581;GLY B 580;TRP B 595","None","1.48A","2y7pA-5m5xB:undetectable","2y7pA-5m5xB:10.81"],["2ZJ0_D_2FAD500_2","ADENOSYLHOMOCYSTEINASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"LEU B 744;GLN B 748;THR B 746;THR B 725","None","1.26A","2zj0D-5m5xB:undetectable","2zj0D-5m5xB:16.78"],["3LTW_A_HLZA300_1","ARYLAMINE N-ACETYLTRANSFERASE NAT","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"PHE B 986;TYR B 995;VAL B 752;PHE B 996","None","1.27A","3ltwA-5m5xB:undetectable","3ltwA-5m5xB:11.92"],["3NK2_X_LDPX433_1","6-HYDROXY-L-NICOTINE OXIDASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"MET B 762;LEU B 703;LEU B  38;PHE B 765","None","1.32A","3nk2X-5m5xB:undetectable","3nk2X-5m5xB:15.63"],["3UJ7_A_SAMA301_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"ILE B1151;ILE B1153;ARG B1134;ASP B1137;ALA B1138","None","1.26A","3uj7A-5m5xB:undetectable","3uj7A-5m5xB:12.02"],["3V4T_D_ACTD502_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",3,"GLY B 727;THR B 725;ASN B 767","None","0.70A","3v4tD-5m5xB:undetectable","3v4tD-5m5xB:16.47"],["4EB4_C_D16C402_1","THYMIDYLATE SYNTHASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"ASP B 841;LEU B 845;GLY B 844;PHE B 825;TYR B 847","None","1.32A","4eb4C-5m5xB:undetectable","4eb4C-5m5xB:13.83"],["4EB4_D_D16D402_1","THYMIDYLATE SYNTHASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"ASP B 841;LEU B 845;GLY B 844;PHE B 825;TYR B 847","None","1.37A","4eb4D-5m5xB:undetectable","4eb4D-5m5xB:13.83"],["4OKB_A_198A1002_2","ANDROGEN RECEPTOR","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"LEU B  61;ASN B  62;LEU B 137;VAL B 155","None","1.02A","4okbA-5m5xB:undetectable","4okbA-5m5xB:12.92"],["4PCU_A_SAMA603_0","CYSTATHIONINE BETA-SYNTHASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"ASP B 946;PRO B 932;ILE B 949;ASP B 782","None","1.04A","4pcuA-5m5xB:undetectable","4pcuA-5m5xB:18.88"],["4YOA_A_017A100_1","HIV-1 PROTEASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"ASN B 755;THR B 692;PRO B 693;THR B 694","None","0.95A","4yoaA-5m5xB:undetectable","4yoaA-5m5xB:6.47"],["5H3A_B_D16B401_1","ORF70","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"ASP B 841;LEU B 845;GLY B 844;PHE B 825;TYR B 847","None","1.30A","5h3aB-5m5xB:undetectable","5h3aB-5m5xB:14.68"],["5IFU_A_GBMA801_1","PROLINE--TRNA LIGASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"TYR B 409;LEU B 413;ARG B 134;ILE B 457;GLY B 458","None","1.17A","5ifuA-5m5xB:undetectable","5ifuA-5m5xB:17.03"],["5IFU_B_GBMB801_1","PROLINE--TRNA LIGASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",6,"ILE B 412;TYR B 409;LEU B 413;ARG B 134;ILE B 457;GLY B 458","None","1.25A","5ifuB-5m5xB:undetectable","5ifuB-5m5xB:17.03"],["5IGW_A_CTYA404_1","MACROLIDE 2'-PHOSPHOTRANSFERASE II","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"ILE B 104;GLY B 135;ILE B 412;TYR B 409;MET B 461","None","1.30A","5igwA-5m5xB:undetectable","5igwA-5m5xB:13.88"],["5IWU_A_ACTA402_0","MACROLIDE 2'-PHOSPHOTRANSFERASE II","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"VAL B1031;MET B 787;ILE B 947;ASP B 946","None","0.96A","5iwuA-5m5xB:undetectable","5iwuA-5m5xB:13.88"],["5MLM_A_STRA401_1","-","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"MET B1013;ILE B1026;VAL B 775;ILE B 776;PRO B 945","None","1.36A","5mlmA-5m5xB:undetectable","5mlmA-5m5xB:15.54"],["5NOO_C_D16C402_1","THYMIDYLATE SYNTHASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"ASP B 841;LEU B 845;GLY B 844;PHE B 825;TYR B 847","None","1.32A","5nooC-5m5xB:undetectable","5nooC-5m5xB:14.31"],["5NOO_C_D16C402_1","THYMIDYLATE SYNTHASE","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",5,"TYR B 861;ASP B 841;LEU B 840;GLY B 844;TYR B 847","None","1.45A","5nooC-5m5xB:undetectable","5nooC-5m5xB:14.31"],["5XV7_A_EMHA705_2","SERINE-ARGININE (SR) PROTEIN KINASE 1","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"VAL B 358;LEU B 359;LEU B 362;ASP B 369","None","1.45A","5xv7A-5m5xB:undetectable","5xv7A-5m5xB:6.10"],["5Z84_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"GLN B 480;PHE B 464;LEU B 465;PHE B 194","None","1.05A","5z84P-5m5xB:undetectable;5z84W-5m5xB:undetectable","5z84P-5m5xB:12.22;5z84W-5m5xB:4.38"],["5Z85_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"GLN B 480;PHE B 464;LEU B 465;PHE B 194","None","1.06A","5z85P-5m5xB:undetectable;5z85W-5m5xB:undetectable","5z85P-5m5xB:12.22;5z85W-5m5xB:4.38"],["5Z86_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"GLN B 480;PHE B 464;LEU B 465;PHE B 194","None","1.04A","5z86P-5m5xB:undetectable;5z86W-5m5xB:undetectable","5z86P-5m5xB:12.22;5z86W-5m5xB:4.38"],["5ZCP_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"GLN B 480;PHE B 464;LEU B 465;PHE B 194","None","1.05A","5zcpP-5m5xB:undetectable;5zcpW-5m5xB:undetectable","5zcpP-5m5xB:12.22;5zcpW-5m5xB:4.38"],["6NKN_W_CHDW102_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5m5x","DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135","Saccharomyces cerevisiae",4,"TYR B 742;ARG B1037;MET B 726;THR B 725","None;  G R  18 ( 4.6A);None;None","1.31A","6nknW-5m5xB:undetectable","6nknW-5m5xB:4.38"]]