SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_B_BZMB600_0
(ODORANT-BINDING
PROTEIN)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 9 ILE A 336
MET A  67
VAL A 356
ASN A 333
GLY A 335
 None
 1.47A 1dzmB-5m6gA:
undetectable		 1dzmB-5m6gA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 5 ASP A  49
ASP A  53
ALA A  39
LEU A  45
 None
 1.16A 1nh8A-5m6gA:
undetectable		 1nh8A-5m6gA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 6 ARG A 417
ILE A 546
TRP A 587
PHE A 606
 None
 1.44A 1nsiA-5m6gA:
undetectable
1nsiB-5m6gA:
undetectable		 1nsiA-5m6gA:
23.23
1nsiB-5m6gA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 6 TRP A 587
PHE A 606
ARG A 417
ILE A 546
 None
 1.49A 1nsiA-5m6gA:
undetectable
1nsiB-5m6gA:
undetectable		 1nsiA-5m6gA:
23.23
1nsiB-5m6gA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 6 ARG A 417
ILE A 546
TRP A 587
PHE A 606
 None
 1.47A 1nsiC-5m6gA:
undetectable
1nsiD-5m6gA:
undetectable		 1nsiC-5m6gA:
23.23
1nsiD-5m6gA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 6 TRP A 587
PHE A 606
ARG A 417
ILE A 546
 None
 1.47A 1nsiC-5m6gA:
undetectable
1nsiD-5m6gA:
undetectable		 1nsiC-5m6gA:
23.23
1nsiD-5m6gA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 12 ASN A  99
LEU A 393
ARG A 390
THR A 460
ILE A 450
 None
 1.41A 1p93B-5m6gA:
undetectable		 1p93B-5m6gA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 ASP A 244
TYR A 503
ASP A 509
HIS A 232
 GOL  A 709 (-3.1A)
None
MG  A 702 (-3.2A)
GOL  A 709 ( 3.4A)
 1.43A 1t03A-5m6gA:
2.2		 1t03A-5m6gA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 4 LEU A  89
SER A 273
ASP A 310
ASP A 315
 None
None
SOR  A 711 ( 3.2A)
None
 1.49A 2br4B-5m6gA:
undetectable		 2br4B-5m6gA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 ARG A 417
ILE A 546
TRP A 587
PHE A 606
 None
 1.40A 2nsiA-5m6gA:
undetectable
2nsiB-5m6gA:
undetectable		 2nsiA-5m6gA:
23.23
2nsiB-5m6gA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 TRP A 587
PHE A 606
ARG A 417
ILE A 546
 None
 1.44A 2nsiA-5m6gA:
undetectable
2nsiB-5m6gA:
undetectable		 2nsiA-5m6gA:
23.23
2nsiB-5m6gA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 ARG A 417
ILE A 546
TRP A 587
PHE A 606
 None
 1.42A 2nsiC-5m6gA:
undetectable
2nsiD-5m6gA:
undetectable		 2nsiC-5m6gA:
23.23
2nsiD-5m6gA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 TRP A 587
PHE A 606
ARG A 417
ILE A 546
 None
 1.43A 2nsiC-5m6gA:
undetectable
2nsiD-5m6gA:
undetectable		 2nsiC-5m6gA:
23.23
2nsiD-5m6gA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 8 MET A 588
LEU A 594
ARG A 510
GLY A 541
 None
 0.97A 2qd5B-5m6gA:
2.3		 2qd5B-5m6gA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 8 ASN A 333
SER A 331
VAL A 361
PHE A 348
 None
 1.23A 2wekA-5m6gA:
3.2		 2wekA-5m6gA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 8 ASN A 333
SER A 331
VAL A 361
PHE A 348
 None
 1.22A 2wekB-5m6gA:
3.1		 2wekB-5m6gA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 ARG A 417
ILE A 546
TRP A 587
PHE A 606
 None
 1.45A 3e7gA-5m6gA:
undetectable
3e7gB-5m6gA:
undetectable		 3e7gA-5m6gA:
21.72
3e7gB-5m6gA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 TRP A 587
PHE A 606
ARG A 417
ILE A 546
 None
 1.49A 3e7gA-5m6gA:
undetectable
3e7gB-5m6gA:
undetectable		 3e7gA-5m6gA:
21.72
3e7gB-5m6gA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 ARG A 417
ILE A 546
TRP A 587
PHE A 606
 None
 1.48A 3e7gC-5m6gA:
undetectable
3e7gD-5m6gA:
undetectable		 3e7gC-5m6gA:
21.72
3e7gD-5m6gA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_C_H4BC3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 ARG A 417
ILE A 546
TRP A 587
PHE A 606
 None
 1.50A 3ej8C-5m6gA:
undetectable
3ej8D-5m6gA:
0.5		 3ej8C-5m6gA:
21.62
3ej8D-5m6gA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 12 GLN A 413
THR A 538
VAL A 537
LEU A 149
ILE A 147
 None
 1.24A 3elzA-5m6gA:
undetectable		 3elzA-5m6gA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 12 THR A 538
VAL A 537
LEU A 149
ILE A 147
THR A 152
 None
 1.25A 3elzA-5m6gA:
undetectable		 3elzA-5m6gA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 11 GLN A 413
THR A 538
VAL A 537
LEU A 149
ILE A 147
 None
 1.35A 3elzB-5m6gA:
undetectable		 3elzB-5m6gA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 11 THR A 538
VAL A 537
LEU A 149
ILE A 147
THR A 152
 None
 1.31A 3elzB-5m6gA:
undetectable		 3elzB-5m6gA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 12 THR A 538
VAL A 537
LEU A 149
ILE A 147
THR A 152
 None
 1.46A 3elzC-5m6gA:
undetectable		 3elzC-5m6gA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		3 / 3 LYS A 347
ARG A 344
ASP A 318
 None
None
MG  A 701 (-2.5A)
 1.22A 3o7wA-5m6gA:
2.1		 3o7wA-5m6gA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_D_DXCD92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 5 VAL A 274
GLU A 252
LYS A 298
PHE A 303
 None
 1.25A 3rv5C-5m6gA:
undetectable
3rv5D-5m6gA:
undetectable		 3rv5C-5m6gA:
9.30
3rv5D-5m6gA:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		3 / 3 SER A 564
GLY A 563
GLN A 444
 None
 0.55A 3v4tH-5m6gA:
undetectable		 3v4tH-5m6gA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_SALA1505_1
(FERROCHELATASE,
MITOCHONDRIAL)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 9 VAL A 414
LEU A 416
PRO A 543
SER A 540
LEU A 583
 None
 1.41A 3w1wA-5m6gA:
2.2
3w1wB-5m6gA:
2.7		 3w1wA-5m6gA:
20.63
3w1wB-5m6gA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_SALA1505_1
(FERROCHELATASE,
MITOCHONDRIAL)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 9 VAL A 414
SER A 540
LEU A 416
PRO A 543
LEU A 583
 None
 1.37A 3w1wA-5m6gA:
2.2
3w1wB-5m6gA:
2.7		 3w1wA-5m6gA:
20.63
3w1wB-5m6gA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		3 / 3 ASP A 458
GLU A 461
GLY A 462
 MG  A 706 ( 4.1A)
None
MG  A 706 (-4.0A)
 0.55A 3w9tA-5m6gA:
undetectable		 3w9tA-5m6gA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 5 GLY A 127
ILE A 125
VAL A 308
SER A  87
 None
 1.26A 4d33A-5m6gA:
undetectable		 4d33A-5m6gA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 5 GLY A 127
ILE A 125
VAL A 308
SER A  87
 None
 1.25A 4d33B-5m6gA:
undetectable		 4d33B-5m6gA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 ALA A 354
VAL A 361
ARG A 329
ARG A 360
 None
 1.13A 4ijiH-5m6gA:
undetectable		 4ijiH-5m6gA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 ALA A 555
LEU A 415
TYR A 614
LEU A 422
 None
 0.95A 4iomA-5m6gA:
2.2		 4iomA-5m6gA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 6 ASP A 520
ASN A 443
TYR A 503
ASP A 517
 None
 1.19A 4mdbA-5m6gA:
undetectable		 4mdbA-5m6gA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 5 ILE A 465
ARG A 406
ASP A 576
VAL A 535
 None
 0.83A 4nkxC-5m6gA:
undetectable		 4nkxC-5m6gA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 5 ILE A 465
ARG A 406
ASP A 576
VAL A 535
 None
 0.79A 4nkxD-5m6gA:
undetectable		 4nkxD-5m6gA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 7 THR A 449
THR A 165
LEU A 149
ASN A 146
 None
 1.08A 4pfjA-5m6gA:
3.9		 4pfjA-5m6gA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 12 GLY A 454
GLY A 442
ILE A 465
TYR A 194
GLN A 413
 None
 0.88A 4rtmA-5m6gA:
undetectable		 4rtmA-5m6gA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 11 ALA A 496
GLY A 435
GLU A 519
GLY A 486
ASN A 485
 None
 1.29A 5ayfA-5m6gA:
undetectable		 5ayfA-5m6gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		3 / 3 ASP A 440
GLU A 519
SER A 451
 None
 0.86A 5bw4B-5m6gA:
2.6		 5bw4B-5m6gA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 12 GLY A 499
ASN A 443
THR A 464
VAL A 536
ALA A 496
 None
 1.04A 5kocA-5m6gA:
undetectable		 5kocA-5m6gA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 12 GLY A 484
ILE A 524
ALA A 494
ASP A 481
ALA A 434
 None
 1.21A 5kvaB-5m6gA:
undetectable		 5kvaB-5m6gA:
18.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 12 ASP A 129
PHE A 178
MET A 275
TRP A 448
GLU A 195
 SOR  A 711 (-3.1A)
SOR  A 711 (-4.6A)
SOR  A 711 (-3.9A)
None
None
 1.43A 5m6gA-5m6gA:
70.0		 5m6gA-5m6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		7 / 12 GLY A  92
ASP A 129
ARG A 192
LYS A 231
HIS A 232
MET A 275
GLU A 505
 SOR  A 711 (-4.1A)
SOR  A 711 (-3.1A)
SOR  A 711 ( 3.0A)
SOR  A 711 (-2.5A)
GOL  A 709 ( 3.4A)
SOR  A 711 (-3.9A)
SOR  A 711 (-3.5A)
 0.93A 5m6gA-5m6gA:
70.0		 5m6gA-5m6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		12 / 12 LEU A  89
GLY A  91
ASP A 129
PHE A 178
ARG A 192
LYS A 231
HIS A 232
MET A 275
TYR A 311
MET A 340
TRP A 448
GLU A 505
 None
SOR  A 711 (-3.5A)
SOR  A 711 (-3.1A)
SOR  A 711 (-4.6A)
SOR  A 711 ( 3.0A)
SOR  A 711 (-2.5A)
GOL  A 709 ( 3.4A)
SOR  A 711 (-3.9A)
SOR  A 711 ( 4.6A)
SOR  A 711 ( 3.7A)
None
SOR  A 711 (-3.5A)
 0.00A 5m6gA-5m6gA:
70.0		 5m6gA-5m6gA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 6 ARG A 482
GLY A 435
THR A 523
GLU A 519
 None
 1.11A 5ny7A-5m6gA:
1.8		 5ny7A-5m6gA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 9 HIS A 134
LEU A 157
ALA A 408
VAL A 409
SER A 412
 None
 1.25A 6c2mB-5m6gA:
undetectable		 6c2mB-5m6gA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 8 LEU A 556
GLU A 549
THR A 538
TRP A 587
 None
 0.90A 6c71B-5m6gA:
undetectable		 6c71B-5m6gA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 6 ILE A 465
LEU A 557
VAL A 497
SER A 559
 None
 1.27A 6f6jA-5m6gA:
undetectable		 6f6jA-5m6gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 6 GLU A 384
ARG A  50
PHE A 378
PRO A 123
 None
 1.42A 6fgdA-5m6gA:
undetectable		 6fgdA-5m6gA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		3 / 3 LYS A  73
SER A 343
SER A 342
 None
 1.07A 6gbfA-5m6gA:
undetectable		 6gbfA-5m6gA:
22.83