SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m6j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5m6j NITROPHORIN-7
(Rhodnius
prolixus) 		5 / 12 TRP A  25
VAL A 111
ALA A 119
ILE A 121
ILE A 123
 None
None
None
None
HEM  A 201 (-4.4A)
 0.86A 1epbA-5m6jA:
15.1		 1epbA-5m6jA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 5m6j NITROPHORIN-7
(Rhodnius
prolixus) 		5 / 10 TYR A  84
VAL A  54
GLY A  23
THR A  24
ALA A  46
 None
 1.30A 2coiA-5m6jA:
undetectable
2coiB-5m6jA:
undetectable		 2coiA-5m6jA:
13.33
2coiB-5m6jA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 5m6j NITROPHORIN-7
(Rhodnius
prolixus) 		4 / 5 ASP A 134
GLU A   4
GLY A   3
ASP A  32
 None
 1.02A 3w9tD-5m6jA:
undetectable		 3w9tD-5m6jA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_B_QMRB1214_1
(CAPITELLA TELETA
ACHBP)		 5m6j NITROPHORIN-7
(Rhodnius
prolixus) 		5 / 9 ILE A 151
ILE A 121
PHE A  45
PHE A  43
VAL A 138
 None
None
HEM  A 201 ( 4.6A)
HEM  A 201 (-3.6A)
None
 1.32A 4afgA-5m6jA:
undetectable
4afgE-5m6jA:
undetectable		 4afgA-5m6jA:
17.67
4afgE-5m6jA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5m6j NITROPHORIN-7
(Rhodnius
prolixus) 		4 / 7 GLU A  49
THR A  53
THR A 108
ASN A  80
 None
 0.88A 4pfjA-5m6jA:
undetectable		 4pfjA-5m6jA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5m6j NITROPHORIN-7
(Rhodnius
prolixus) 		4 / 6 GLU A  49
THR A  53
THR A 108
ASN A  80
 None
 0.92A 4pfjB-5m6jA:
undetectable		 4pfjB-5m6jA:
11.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 5m6j NITROPHORIN-7
(Rhodnius
prolixus) 		3 / 3 ASP A  32
LEU A 125
GLY A 133
 None
 0.12A 4xmfA-5m6jA:
36.4		 4xmfA-5m6jA:
98.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5m6j NITROPHORIN-7
(Rhodnius
prolixus) 		3 / 3 LYS A 185
LYS A 178
SER A 181
 None
 1.29A 5odiA-5m6jA:
undetectable		 5odiA-5m6jA:
undetectable