SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m6m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PEO_F_CU9F301_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5m6m	E3 UBIQUITIN-PROTEIN LIGASE XIAP (Homo sapiens)	4 / 7	TRP A 310 TYR A 329 CYH A 327 CYH A 303	7H8 A 403 (-2.8A) None ZN A 401 (-2.2A) ZN A 401 (-2.3A)	1.15A	3peoF-5m6mA: 0.0	3peoF-5m6mA: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_I_ACTI507_0 (RNA POLYMERASE 3D-POL)	5m6m	E3 UBIQUITIN-PROTEIN LIGASE XIAP (Homo sapiens)	3 / 3	LYS A 311 PRO A 312 SER A 313	None	0.30A	4k50I-5m6mA: undetectable	4k50I-5m6mA: 12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W7P_A_SAMA501_0 (OXAC)	5m6m	E3 UBIQUITIN-PROTEIN LIGASE XIAP (Homo sapiens)	5 / 12	GLY A 288 LEU A 307 VAL A 298 ARG A 286 ASP A 315	None 7H8 A 403 (-3.4A) 7H8 A 403 (-4.8A) None None	1.15A	5w7pA-5m6mA: undetectable	5w7pA-5m6mA: 17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6ESM_A_PZEA307_1 (MATRIX METALLOPROTEINASE-9, MATRIX METALLOPROTEINASE-9)	5m6m	E3 UBIQUITIN-PROTEIN LIGASE XIAP (Homo sapiens)	3 / 3	TYR A 329 HIS A 302 PHE A 301	None	0.93A	6esmA-5m6mA: undetectable	6esmA-5m6mA: 18.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3PEO_F_CU9F301_1","SOLUBLE ACETYLCHOLINE RECEPTOR","5m6m","E3 UBIQUITIN-PROTEIN LIGASE XIAP","Homo sapiens",4,"TRP A 310;TYR A 329;CYH A 327;CYH A 303","7H8 A 403 (-2.8A);None; ZN A 401 (-2.2A); ZN A 401 (-2.3A)","1.15A","3peoF-5m6mA:0.0","3peoF-5m6mA:20.09"],["4K50_I_ACTI507_0","RNA POLYMERASE 3D-POL","5m6m","E3 UBIQUITIN-PROTEIN LIGASE XIAP","Homo sapiens",3,"LYS A 311;PRO A 312;SER A 313","None","0.30A","4k50I-5m6mA:undetectable","4k50I-5m6mA:12.09"],["5W7P_A_SAMA501_0","OXAC","5m6m","E3 UBIQUITIN-PROTEIN LIGASE XIAP","Homo sapiens",5,"GLY A 288;LEU A 307;VAL A 298;ARG A 286;ASP A 315","None;7H8 A 403 (-3.4A);7H8 A 403 (-4.8A);None;None","1.15A","5w7pA-5m6mA:undetectable","5w7pA-5m6mA:17.35"],["6ESM_A_PZEA307_1","MATRIX METALLOPROTEINASE-9,MATRIX METALLOPROTEINASE-9","5m6m","E3 UBIQUITIN-PROTEIN LIGASE XIAP","Homo sapiens",3,"TYR A 329;HIS A 302;PHE A 301","None","0.93A","6esmA-5m6mA:undetectable","6esmA-5m6mA:18.11"]]