SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		4 / 6 HIS A 188
ASP A  21
TYR A  22
HIS A 205
 None
PG4  A 305 (-3.6A)
None
MES  A 303 (-4.0A)
 1.27A 2einA-5m6qA:
undetectable
2einC-5m6qA:
undetectable		 2einA-5m6qA:
18.98
2einC-5m6qA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		4 / 6 GLN A  78
ASN A  82
ASN A 109
LEU A 107
 None
None
MES  A 301 ( 3.8A)
None
 1.26A 2nyrA-5m6qA:
undetectable		 2nyrA-5m6qA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		4 / 8 LEU A  59
LEU A  64
ASN A  65
ARG A  56
 None
None
MES  A 301 (-3.5A)
None
 1.11A 2xn3A-5m6qA:
undetectable
2xn3B-5m6qA:
undetectable		 2xn3A-5m6qA:
19.83
2xn3B-5m6qA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		4 / 8 VAL A 217
GLY A  69
PRO A 151
LYS A 130
 None
 0.89A 3bjwA-5m6qA:
undetectable		 3bjwA-5m6qA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		4 / 5 ASP A 175
TYR A 176
PRO A  62
LYS A  47
 CME  A  46 ( 4.2A)
None
None
CME  A  46 ( 2.9A)
 1.33A 3h1xA-5m6qA:
undetectable		 3h1xA-5m6qA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		3 / 3 ASN A  53
TRP A 178
ASP A 226
 None
 1.23A 4a7tA-5m6qA:
undetectable
4a7tF-5m6qA:
undetectable		 4a7tA-5m6qA:
20.18
4a7tF-5m6qA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		5 / 12 ASP A 182
TRP A 178
ALA A 125
ALA A 223
ASN A  82
 None
 1.44A 4u14A-5m6qA:
undetectable		 4u14A-5m6qA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		3 / 3 MET A  34
GLU A  38
LEU A  42
 None
 0.77A 4v2oB-5m6qA:
undetectable		 4v2oB-5m6qA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		5 / 12 LEU A 123
LYS A 122
ASN A  55
LEU A  54
ALA A 221
 None
 1.37A 5kbwA-5m6qA:
undetectable		 5kbwA-5m6qA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		4 / 7 TYR A  22
TRP A 187
TYR A  29
TRP A  17
 None
None
None
PG4  A 305 ( 4.2A)
 1.21A 6cnjA-5m6qA:
undetectable
6cnjB-5m6qA:
undetectable		 6cnjA-5m6qA:
15.56
6cnjB-5m6qA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		4 / 8 TYR A  22
TRP A 187
TYR A  29
TRP A  17
 None
None
None
PG4  A 305 ( 4.2A)
 1.14A 6cnjD-5m6qA:
undetectable
6cnjE-5m6qA:
undetectable		 6cnjD-5m6qA:
15.56
6cnjE-5m6qA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_B_NCTB402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		4 / 7 TYR A  22
TRP A 187
TYR A  29
TRP A  17
 None
None
None
PG4  A 305 ( 4.2A)
 1.18A 6cnkB-5m6qA:
undetectable
6cnkC-5m6qA:
undetectable		 6cnkB-5m6qA:
15.56
6cnkC-5m6qA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		5 / 10 LEU A 107
VAL A 110
ILE A  84
ALA A  76
LEU A  81
 None
 1.10A 6h1lA-5m6qA:
undetectable		 6h1lA-5m6qA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5m6q UNCHARACTERIZED
PROTEIN
(Kutzneria
albida) 		4 / 6 HIS A 188
ASP A  21
TYR A  22
HIS A 205
 None
PG4  A 305 (-3.6A)
None
MES  A 303 (-4.0A)
 1.24A 6nknA-5m6qA:
undetectable
6nknC-5m6qA:
undetectable		 6nknA-5m6qA:
18.98
6nknC-5m6qA:
19.31