SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 5m72 SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP68
SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP72
(Homo
sapiens) 		5 / 12 THR A  46
ALA A  47
ASP A  44
LEU A  31
LEU B 603
 None
 1.23A 1errA-5m72A:
undetectable		 1errA-5m72A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 5m72 SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP72
SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP68
(Homo
sapiens;
Homo
sapiens) 		4 / 8 LEU A 135
GLY A 116
TYR A 132
HIS B 597
 None
 0.86A 3af0A-5m72A:
undetectable		 3af0A-5m72A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 5m72 SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP72
(Homo
sapiens) 		5 / 9 ASP A  44
ALA A  47
PRO A  12
VAL A  11
ILE A  37
 None
 1.10A 3em4B-5m72A:
undetectable		 3em4B-5m72A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 5m72 SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP72
(Homo
sapiens) 		5 / 11 ASP A  44
ALA A  47
PRO A  12
VAL A  11
ILE A  37
 None
 1.11A 3oxxB-5m72A:
undetectable		 3oxxB-5m72A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5m72 SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP72
(Homo
sapiens) 		4 / 7 TYR A  86
ARG A  93
ILE A  94
ALA A  97
 None
 0.70A 4lv9B-5m72A:
undetectable		 4lv9B-5m72A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5m72 SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP68
SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP72
(Homo
sapiens) 		4 / 7 ASN A  35
LYS A  32
TYR A  21
LEU B 603
 None
None
GOL  A 204 (-3.9A)
None
 1.22A 4yv5A-5m72A:
undetectable		 4yv5A-5m72A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5m72 SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP68
SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP72
(Homo
sapiens) 		4 / 7 ASN A  35
LYS A  32
TYR A  21
LEU B 603
 None
None
GOL  A 204 (-3.9A)
None
 1.04A 4yv5B-5m72A:
undetectable		 4yv5B-5m72A:
22.50