SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m8i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZXW_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	5m8i	CUGBP ELAV-LIKE FAMILY MEMBER 2 (Homo sapiens)	4 / 7	ILE A 95 LEU A 100 PHE A 93 MET A 48	None	1.15A	2zxwN-5m8iA: undetectable 2zxwW-5m8iA: undetectable	2zxwN-5m8iA: 12.57 2zxwW-5m8iA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QPS_A_CHDA211_0 (CMER)	5m8i	CUGBP ELAV-LIKE FAMILY MEMBER 2 (Homo sapiens)	5 / 10	ALA A 58 PHE A 74 GLY A 73 ILE A 33 PHE A 52	None A B 118 ( 3.3A) None None None	1.46A	3qpsA-5m8iA: undetectable	3qpsA-5m8iA: 20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_B_SAMB801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	5m8i	CUGBP ELAV-LIKE FAMILY MEMBER 2 (Homo sapiens)	5 / 11	ILE A 45 GLY A 73 ALA A 58 LEU A 46 VAL A 55	None	1.21A	5hw4B-5m8iA: undetectable	5hw4B-5m8iA: 16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6J21_A_GBQA1201_0 (SUBSTANCE-P RECEPTOR,ENDOLYSIN)	5m8i	CUGBP ELAV-LIKE FAMILY MEMBER 2 (Homo sapiens)	5 / 12	ILE A 33 VAL A 75 ILE A 95 VAL A 102 PHE A 52	None	1.29A	6j21A-5m8iA: undetectable	6j21A-5m8iA: 12.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZXW_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","5m8i","CUGBP ELAV-LIKE FAMILY MEMBER 2","Homo sapiens",4,"ILE A  95;LEU A 100;PHE A  93;MET A  48","None","1.15A","2zxwN-5m8iA:undetectable;2zxwW-5m8iA:undetectable","2zxwN-5m8iA:12.57;2zxwW-5m8iA:18.75"],["3QPS_A_CHDA211_0","CMER","5m8i","CUGBP ELAV-LIKE FAMILY MEMBER 2","Homo sapiens",5,"ALA A  58;PHE A  74;GLY A  73;ILE A  33;PHE A  52","None;  A B 118 ( 3.3A);None;None;None","1.46A","3qpsA-5m8iA:undetectable","3qpsA-5m8iA:20.91"],["5HW4_B_SAMB801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","5m8i","CUGBP ELAV-LIKE FAMILY MEMBER 2","Homo sapiens",5,"ILE A  45;GLY A  73;ALA A  58;LEU A  46;VAL A  55","None","1.21A","5hw4B-5m8iA:undetectable","5hw4B-5m8iA:16.88"],["6J21_A_GBQA1201_0","SUBSTANCE-P RECEPTOR,ENDOLYSIN","5m8i","CUGBP ELAV-LIKE FAMILY MEMBER 2","Homo sapiens",5,"ILE A  33;VAL A  75;ILE A  95;VAL A 102;PHE A  52","None","1.29A","6j21A-5m8iA:undetectable","6j21A-5m8iA:12.76"]]