SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m99'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_A_QPSA1001_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	7 / 12	HIS B 81 TYR B 83 ASP B 213 ALA B 214 HIS B 304 ASP B 367 ARG B 371	None K B 605 ( 3.2A) EDO B 616 ( 2.8A) EDO B 616 ( 4.7A) None None None	0.92A	1dedA-5m99B: 30.4	1dedA-5m99B: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_A_QPSA1001_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 12	HIS B 81 TYR B 83 GLU B 253 HIS B 304 ASP B 367 ARG B 371	None K B 605 ( 3.2A) K B 605 ( 4.7A) None None None	1.27A	1dedA-5m99B: 30.4	1dedA-5m99B: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_A_QPSA1001_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	7 / 12	TYR B 83 ASP B 213 ALA B 214 HIS B 304 ASP B 305 ASP B 367 ARG B 371	K B 605 ( 3.2A) EDO B 616 ( 2.8A) EDO B 616 ( 4.7A) None K B 605 ( 4.7A) None None	0.93A	1dedA-5m99B: 30.4	1dedA-5m99B: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_A_QPSA1001_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 12	TYR B 83 GLU B 253 HIS B 304 ASP B 305 ASP B 367 ARG B 371	K B 605 ( 3.2A) K B 605 ( 4.7A) None K B 605 ( 4.7A) None None	1.26A	1dedA-5m99B: 30.4	1dedA-5m99B: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_B_QPSB1501_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	10 / 12	HIS B 81 TYR B 83 ARG B 211 ASP B 213 ALA B 214 GLU B 253 PHE B 255 HIS B 304 ASP B 305 ARG B 371	None K B 605 ( 3.2A) K B 605 ( 4.8A) EDO B 616 ( 2.8A) EDO B 616 ( 4.7A) K B 605 ( 4.7A) None None K B 605 ( 4.7A) None	0.79A	1dedB-5m99B: 28.5	1dedB-5m99B: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ESW_A_ACRA652_1 (AMYLOMALTASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 6	TYR B 41 GLY B 53 ASP B 50 GLY B 45	None None NA B 602 (-3.4A) None	0.73A	1eswA-5m99B: 17.0	1eswA-5m99B: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ESW_A_ACRA652_1 (AMYLOMALTASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 6	TYR B 393 GLY B 407 ASP B 406 GLY B 401	None None NA B 601 (-2.3A) NA B 601 (-4.2A)	1.00A	1eswA-5m99B: 17.0	1eswA-5m99B: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GWR_B_ESTB600_1 (OESTROGEN RECEPTOR)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 9	LEU B 338 LEU B 301 MET B 275 HIS B 316 LEU B 313	None	1.39A	1gwrB-5m99B: undetectable	1gwrB-5m99B: 18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KXH_A_ACRA598_1 (ALPHA-AMYLASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 12	HIS B 123 GLY B 178 ALA B 214 GLU B 253 ASP B 305	EDO B 616 (-4.3A) None EDO B 616 ( 4.7A) K B 605 ( 4.7A) K B 605 ( 4.7A)	0.40A	1kxhA-5m99B: 21.8	1kxhA-5m99B: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXD_A_ACRA735_1 (ALPHA AMYLASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	8 / 12	TYR B 83 HIS B 123 ARG B 211 ASP B 213 LYS B 216 GLU B 253 HIS B 304 ASP B 305	K B 605 ( 3.2A) EDO B 616 (-4.3A) K B 605 ( 4.8A) EDO B 616 ( 2.8A) None K B 605 ( 4.7A) None K B 605 ( 4.7A)	0.37A	1mxdA-5m99B: 25.5	1mxdA-5m99B: 24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXD_A_ACRA735_1 (ALPHA AMYLASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	8 / 12	TYR B 83 HIS B 123 PHE B 177 ARG B 211 ASP B 213 GLU B 253 HIS B 304 ASP B 305	K B 605 ( 3.2A) EDO B 616 (-4.3A) EDO B 616 ( 3.8A) K B 605 ( 4.8A) EDO B 616 ( 2.8A) K B 605 ( 4.7A) None K B 605 ( 4.7A)	0.99A	1mxdA-5m99B: 25.5	1mxdA-5m99B: 24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_B_DVAB8_0 (GRAMICIDIN A)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 5	VAL B 207 GLY B 209 VAL B 115 TRP B 70	None	1.25A	1tkqB-5m99B: undetectable	1tkqB-5m99B: 4.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VPT_A_SAMA400_0 (VP39)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 12	ILE B 35 VAL B 54 VAL B 69 ALA B 68 LEU B 61	None	1.01A	1vptA-5m99B: undetectable	1vptA-5m99B: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAT_A_FK5A108_1 (FK506 BINDING PROTEIN)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 11	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.31A	1yatA-5m99B: undetectable	1yatA-5m99B: 14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BTE_A_LEUA1894_0 (AMINOACYL-TRNA SYNTHETASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 8	MET B 72 TYR B 80 TYR B 83 HIS B 304	None None K B 605 ( 3.2A) None	1.09A	2bteA-5m99B: undetectable	2bteA-5m99B: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BTE_D_LEUD1893_0 (AMINOACYL-TRNA SYNTHETASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 8	MET B 72 TYR B 80 TYR B 83 HIS B 304	None None K B 605 ( 3.2A) None	1.07A	2bteD-5m99B: 2.5	2bteD-5m99B: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BYT_A_LEUA1301_0 (LEUCYL-TRNA SYNTHETASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 7	MET B 72 TYR B 80 TYR B 83 HIS B 304	None None K B 605 ( 3.2A) None	1.11A	2bytA-5m99B: 2.2	2bytA-5m99B: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BYT_D_LEUD1601_0 (LEUCYL-TRNA SYNTHETASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 7	MET B 72 TYR B 80 TYR B 83 HIS B 304	None None K B 605 ( 3.2A) None	1.10A	2bytD-5m99B: undetectable	2bytD-5m99B: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KOT_A_ANWA99_0 (PROTEIN S100-A13)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 7	VAL B 474 PHE B 463 THR B 452 LYS B 343	None	0.98A	2kotA-5m99B: undetectable	2kotA-5m99B: 11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KOT_B_ANWB99_0 (PROTEIN S100-A13)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 8	VAL B 474 PHE B 463 THR B 452 LYS B 343	None	1.15A	2kotB-5m99B: undetectable	2kotB-5m99B: 11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0G_A_LEUA1887_0 (AMINOACYL-TRNA SYNTHETASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 8	MET B 72 TYR B 80 TYR B 83 HIS B 304	None None K B 605 ( 3.2A) None	1.15A	2v0gA-5m99B: 2.5	2v0gA-5m99B: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDV_E_SAME1287_0 (TRNA (GUANINE-N(7)-)-METH YLTRANSFERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 12	GLY B 49 GLY B 47 ASN B 52 ASP B 94 THR B 389	NA B 602 ( 4.8A) None None None None	1.12A	2vdvE-5m99B: undetectable	2vdvE-5m99B: 17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDV_F_SAMF1287_0 (TRNA (GUANINE-N(7)-)-METH YLTRANSFERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 11	GLY B 49 GLY B 47 ASN B 52 ASP B 94 THR B 389	NA B 602 ( 4.8A) None None None None	1.12A	2vdvF-5m99B: undetectable	2vdvF-5m99B: 17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZI9_A_CL9A401_1 (DEOXYCYTIDINE KINASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 12	GLU B 253 MET B 275 TYR B 276 PHE B 300 ARG B 211	K B 605 ( 4.7A) None None None K B 605 ( 4.8A)	1.06A	2zi9A-5m99B: 0.0	2zi9A-5m99B: 18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_A_ACRA5044_1 (GLUCOSYLTRANSFERASE- SI)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 12	ARG B 211 ASP B 213 ALA B 214 GLU B 253 HIS B 304 ASP B 305	K B 605 ( 4.8A) EDO B 616 ( 2.8A) EDO B 616 ( 4.7A) K B 605 ( 4.7A) None K B 605 ( 4.7A)	0.64A	3aicA-5m99B: 3.3	3aicA-5m99B: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_B_ACRB5044_1 (GLUCOSYLTRANSFERASE- SI)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 12	ARG B 211 ASP B 213 ALA B 214 GLU B 253 HIS B 304 ASP B 305	K B 605 ( 4.8A) EDO B 616 ( 2.8A) EDO B 616 ( 4.7A) K B 605 ( 4.7A) None K B 605 ( 4.7A)	0.64A	3aicB-5m99B: 5.1	3aicB-5m99B: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_C_ACRC5044_1 (GLUCOSYLTRANSFERASE- SI)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	7 / 12	ARG B 211 ASP B 213 ALA B 214 GLU B 253 HIS B 304 ASP B 305 TYR B 83	K B 605 ( 4.8A) EDO B 616 ( 2.8A) EDO B 616 ( 4.7A) K B 605 ( 4.7A) None K B 605 ( 4.7A) K B 605 ( 3.2A)	0.63A	3aicC-5m99B: 7.6	3aicC-5m99B: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_D_ACRD5044_1 (GLUCOSYLTRANSFERASE- SI)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 12	ARG B 211 ASP B 213 ALA B 214 GLU B 253 HIS B 304 ASP B 305	K B 605 ( 4.8A) EDO B 616 ( 2.8A) EDO B 616 ( 4.7A) K B 605 ( 4.7A) None K B 605 ( 4.7A)	0.70A	3aicD-5m99B: 4.0	3aicD-5m99B: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_E_ACRE5044_1 (GLUCOSYLTRANSFERASE- SI)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 12	ARG B 211 ASP B 213 ALA B 214 GLU B 253 HIS B 304 ASP B 305	K B 605 ( 4.8A) EDO B 616 ( 2.8A) EDO B 616 ( 4.7A) K B 605 ( 4.7A) None K B 605 ( 4.7A)	0.68A	3aicE-5m99B: 8.0	3aicE-5m99B: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_F_ACRF5044_1 (GLUCOSYLTRANSFERASE- SI)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 12	ARG B 211 ASP B 213 ALA B 214 GLU B 253 HIS B 304 ASP B 305	K B 605 ( 4.8A) EDO B 616 ( 2.8A) EDO B 616 ( 4.7A) K B 605 ( 4.7A) None K B 605 ( 4.7A)	0.63A	3aicF-5m99B: undetectable	3aicF-5m99B: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_G_ACRG5044_1 (GLUCOSYLTRANSFERASE- SI)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 12	ARG B 211 ASP B 213 ALA B 214 GLU B 253 HIS B 304 ASP B 305	K B 605 ( 4.8A) EDO B 616 ( 2.8A) EDO B 616 ( 4.7A) K B 605 ( 4.7A) None K B 605 ( 4.7A)	0.62A	3aicG-5m99B: 8.0	3aicG-5m99B: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_H_ACRH5044_1 (GLUCOSYLTRANSFERASE- SI)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 12	ARG B 211 ASP B 213 ALA B 214 GLU B 253 HIS B 304 ASP B 305	K B 605 ( 4.8A) EDO B 616 ( 2.8A) EDO B 616 ( 4.7A) K B 605 ( 4.7A) None K B 605 ( 4.7A)	0.71A	3aicH-5m99B: 6.3	3aicH-5m99B: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AXZ_A_ADNA401_1 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 12	LEU B 40 SER B 39 PRO B 373 GLY B 47 GLY B 384	None	1.09A	3axzA-5m99B: undetectable	3axzA-5m99B: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BXO_A_SAMA238_1 (N,N-DIMETHYLTRANSFER ASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	3 / 3	TYR B 336 GLU B 34 ASP B 213	None None EDO B 616 ( 2.8A)	0.64A	3bxoA-5m99B: undetectable	3bxoA-5m99B: 18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BXO_B_SAMB238_1 (N,N-DIMETHYLTRANSFER ASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	3 / 3	TYR B 336 GLU B 34 ASP B 213	None None EDO B 616 ( 2.8A)	0.70A	3bxoB-5m99B: undetectable	3bxoB-5m99B: 18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPB_C_SAMC1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 12	HIS B 81 VAL B 120 ILE B 85 SER B 79 PRO B 73	None	1.01A	3kpbC-5m99B: undetectable	3kpbC-5m99B: 12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KZ7_A_RAPA225_1 (FK506-BINDING PROTEIN 3)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 10	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.23A	3kz7A-5m99B: undetectable	3kz7A-5m99B: 13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NAI_C_URFC521_1 (RNA DEPENDENT RNA POLYMERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 5	ARG B 38 ASP B 42 ASP B 46 ASP B 44	None NA B 602 (-3.2A) NA B 602 (-2.9A) NA B 602 (-3.1A)	1.48A	3naiC-5m99B: undetectable	3naiC-5m99B: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UGR_A_IMNA2001_2 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 7	TYR B 349 GLU B 368 TYR B 366 TYR B 393	None	1.26A	3ugrA-5m99B: 7.7	3ugrA-5m99B: 20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VAW_A_FK5A114_1 (UBIQUITIN-LIKE PROTEIN SMT3,PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 11	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.29A	3vawA-5m99B: undetectable	3vawA-5m99B: 18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WEO_A_ACRA1001_2 (ALPHA-GLUCOSIDASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 6	ILE B 35 ILE B 203 TRP B 202 MET B 117	None	1.40A	3weoA-5m99B: 13.5	3weoA-5m99B: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_E_ZPCE1318_2 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 6	GLU B 302 PHE B 310 TYR B 336 PHE B 309	None	1.19A	4a97E-5m99B: undetectable	4a97E-5m99B: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_B_DXCB1473_0 (MJ0495-LIKE PROTEIN)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 11	ILE B 121 ASP B 213 ILE B 212 PHE B 237 VAL B 241 GLY B 209	None EDO B 616 ( 2.8A) None None None None	1.37A	4ac9B-5m99B: 3.3 4ac9C-5m99B: 2.1	4ac9B-5m99B: 19.38 4ac9C-5m99B: 19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DRI_A_RAPA201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 11	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.22A	4driA-5m99B: undetectable	4driA-5m99B: 15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DZ2_A_FK5A200_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 11	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.25A	4dz2A-5m99B: undetectable 4dz2B-5m99B: undetectable	4dz2A-5m99B: 12.67 4dz2B-5m99B: 12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DZ2_B_FK5B200_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 11	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.28A	4dz2A-5m99B: undetectable 4dz2B-5m99B: undetectable	4dz2A-5m99B: 12.67 4dz2B-5m99B: 12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DZ3_A_FK5A201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 10	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.28A	4dz3A-5m99B: undetectable	4dz3A-5m99B: 12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DZ3_B_FK5B201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 10	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.28A	4dz3B-5m99B: undetectable	4dz3B-5m99B: 12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E7C_D_ACTD504_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	3 / 3	GLY B 156 SER B 155 TRP B 172	None	0.95A	4e7cD-5m99B: undetectable	4e7cD-5m99B: 22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEV_D_KAND301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 7	ASP B 213 ASP B 367 ASP B 305 GLU B 253	EDO B 616 ( 2.8A) None K B 605 ( 4.7A) K B 605 ( 4.7A)	1.23A	4fevD-5m99B: 4.3	4fevD-5m99B: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NNR_A_FK5A201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 12	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.24A	4nnrA-5m99B: undetectable 4nnrB-5m99B: undetectable	4nnrA-5m99B: 14.80 4nnrB-5m99B: 14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NNR_B_FK5B201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 10	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.18A	4nnrB-5m99B: undetectable	4nnrB-5m99B: 14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QT2_A_RAPA202_1 (FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 10	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.21A	4qt2A-5m99B: undetectable	4qt2A-5m99B: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BPH_B_ACTB404_0 (D-ALANINE--D-ALANINE LIGASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 7	TYR B 60 TYR B 33 GLY B 352 LEU B 430	EDO B 609 (-4.9A) None None None	1.12A	5bphB-5m99B: undetectable	5bphB-5m99B: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSY_B_ACRB601_1 (4-ALPHA-GLUCANOTRANS FERASE DPE1, CHLOROPLASTIC/AMYLOP LASTIC)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 12	ARG B 211 ASP B 213 GLU B 253 HIS B 304 ASP B 305	K B 605 ( 4.8A) EDO B 616 ( 2.8A) K B 605 ( 4.7A) None K B 605 ( 4.7A)	0.45A	5csyB-5m99B: 18.7	5csyB-5m99B: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DX3_A_ESTA601_1 (ESTROGEN RECEPTOR)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 10	LEU B 338 LEU B 301 MET B 275 HIS B 316 LEU B 313	None	1.38A	5dx3A-5m99B: undetectable	5dx3A-5m99B: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HWC_A_FK5A201_1 (FK506-BINDING PROTEIN 1A)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 11	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.23A	5hwcA-5m99B: undetectable	5hwcA-5m99B: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HYR_B_ESTB601_1 (ESTROGEN RECEPTOR)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 11	LEU B 338 LEU B 301 MET B 275 HIS B 316 LEU B 313	None	1.41A	5hyrB-5m99B: undetectable	5hyrB-5m99B: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IFU_B_GBMB801_1 (PROLINE--TRNA LIGASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 9	TYR B 33 ILE B 433 TYR B 336 LEU B 429 GLU B 302	None	1.33A	5ifuB-5m99B: undetectable	5ifuB-5m99B: 20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L6E_A_SAMA601_1 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 6	ASP B 100 ASN B 111 ASN B 103 GLN B 106	None EDO B 615 (-3.2A) None None	1.16A	5l6eA-5m99B: undetectable	5l6eA-5m99B: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NO9_D_95ZD302_1 (25 KDA PROTEIN ELICITOR)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	4 / 7	GLY B 209 ASP B 247 HIS B 109 ASP B 208	None	1.07A	5no9D-5m99B: undetectable	5no9D-5m99B: 10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VEU_B_RITB602_1 (CYTOCHROME P450 3A5)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 12	PHE B 454 PHE B 337 PHE B 486 ALA B 445 ILE B 446	None	1.06A	5veuB-5m99B: undetectable	5veuB-5m99B: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_A_ACRA610_0 (ALPHA-AMYLASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	7 / 12	TYR B 83 HIS B 123 ASP B 213 LYS B 216 HIS B 217 HIS B 304 ASP B 305	K B 605 ( 3.2A) EDO B 616 (-4.3A) EDO B 616 ( 2.8A) None NA B 604 ( 4.9A) None K B 605 ( 4.7A)	0.50A	6ag0A-5m99B: 22.1	6ag0A-5m99B: 10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_A_ACRA610_0 (ALPHA-AMYLASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 12	TYR B 83 HIS B 123 MET B 181 ASP B 213 HIS B 304 ASP B 305	K B 605 ( 3.2A) EDO B 616 (-4.3A) EDO B 616 ( 4.1A) EDO B 616 ( 2.8A) None K B 605 ( 4.7A)	0.99A	6ag0A-5m99B: 22.1	6ag0A-5m99B: 10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_C_ACRC608_0 (ALPHA-AMYLASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	6 / 12	ASP B 213 LYS B 216 HIS B 217 TYR B 276 HIS B 304 ASP B 305	EDO B 616 ( 2.8A) None NA B 604 ( 4.9A) None None K B 605 ( 4.7A)	0.85A	6ag0C-5m99B: 22.1	6ag0C-5m99B: 10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CBZ_B_ESTB602_1 (ESTROGEN RECEPTOR)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 10	LEU B 338 LEU B 301 MET B 275 HIS B 316 LEU B 313	None	1.36A	6cbzB-5m99B: undetectable	6cbzB-5m99B: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MKE_C_FK5C201_1 (PEPTIDYLPROLYL ISOMERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 10	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.25A	6mkeC-5m99B: undetectable	6mkeC-5m99B: 10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MKE_D_FK5D201_1 (PEPTIDYLPROLYL ISOMERASE)	5m99	ALPHA-AMYLASE (Thermotoga petrophila)	5 / 10	ASP B 213 VAL B 195 ILE B 198 TYR B 88 ILE B 85	EDO B 616 ( 2.8A) None None None None	1.30A	6mkeD-5m99B: undetectable	6mkeD-5m99B: 10.54

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DED_A_QPSA1001_1","CYCLODEXTRIN GLUCANOTRANSFERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",7,"HIS B  81;TYR B  83;ASP B 213;ALA B 214;HIS B 304;ASP B 367;ARG B 371","None;  K B 605 ( 3.2A);EDO B 616 ( 2.8A);EDO B 616 ( 4.7A);None;None;None","0.92A","1dedA-5m99B:30.4","1dedA-5m99B:24.32"],["1DED_A_QPSA1001_1","CYCLODEXTRIN GLUCANOTRANSFERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"HIS B  81;TYR B  83;GLU B 253;HIS B 304;ASP B 367;ARG B 371","None;  K B 605 ( 3.2A);  K B 605 ( 4.7A);None;None;None","1.27A","1dedA-5m99B:30.4","1dedA-5m99B:24.32"],["1DED_A_QPSA1001_1","CYCLODEXTRIN GLUCANOTRANSFERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",7,"TYR B  83;ASP B 213;ALA B 214;HIS B 304;ASP B 305;ASP B 367;ARG B 371","  K B 605 ( 3.2A);EDO B 616 ( 2.8A);EDO B 616 ( 4.7A);None;  K B 605 ( 4.7A);None;None","0.93A","1dedA-5m99B:30.4","1dedA-5m99B:24.32"],["1DED_A_QPSA1001_1","CYCLODEXTRIN GLUCANOTRANSFERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"TYR B  83;GLU B 253;HIS B 304;ASP B 305;ASP B 367;ARG B 371","  K B 605 ( 3.2A);  K B 605 ( 4.7A);None;  K B 605 ( 4.7A);None;None","1.26A","1dedA-5m99B:30.4","1dedA-5m99B:24.32"],["1DED_B_QPSB1501_1","CYCLODEXTRIN GLUCANOTRANSFERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",10,"HIS B  81;TYR B  83;ARG B 211;ASP B 213;ALA B 214;GLU B 253;PHE B 255;HIS B 304;ASP B 305;ARG B 371","None;  K B 605 ( 3.2A);  K B 605 ( 4.8A);EDO B 616 ( 2.8A);EDO B 616 ( 4.7A);  K B 605 ( 4.7A);None;None;  K B 605 ( 4.7A);None","0.79A","1dedB-5m99B:28.5","1dedB-5m99B:24.32"],["1ESW_A_ACRA652_1","AMYLOMALTASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"TYR B  41;GLY B  53;ASP B  50;GLY B  45","None;None; NA B 602 (-3.4A);None","0.73A","1eswA-5m99B:17.0","1eswA-5m99B:19.63"],["1ESW_A_ACRA652_1","AMYLOMALTASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"TYR B 393;GLY B 407;ASP B 406;GLY B 401","None;None; NA B 601 (-2.3A); NA B 601 (-4.2A)","1.00A","1eswA-5m99B:17.0","1eswA-5m99B:19.63"],["1GWR_B_ESTB600_1","OESTROGEN RECEPTOR","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"LEU B 338;LEU B 301;MET B 275;HIS B 316;LEU B 313","None","1.39A","1gwrB-5m99B:undetectable","1gwrB-5m99B:18.83"],["1KXH_A_ACRA598_1","ALPHA-AMYLASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"HIS B 123;GLY B 178;ALA B 214;GLU B 253;ASP B 305","EDO B 616 (-4.3A);None;EDO B 616 ( 4.7A);  K B 605 ( 4.7A);  K B 605 ( 4.7A)","0.40A","1kxhA-5m99B:21.8","1kxhA-5m99B:22.51"],["1MXD_A_ACRA735_1","ALPHA AMYLASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",8,"TYR B  83;HIS B 123;ARG B 211;ASP B 213;LYS B 216;GLU B 253;HIS B 304;ASP B 305","  K B 605 ( 3.2A);EDO B 616 (-4.3A);  K B 605 ( 4.8A);EDO B 616 ( 2.8A);None;  K B 605 ( 4.7A);None;  K B 605 ( 4.7A)","0.37A","1mxdA-5m99B:25.5","1mxdA-5m99B:24.45"],["1MXD_A_ACRA735_1","ALPHA AMYLASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",8,"TYR B  83;HIS B 123;PHE B 177;ARG B 211;ASP B 213;GLU B 253;HIS B 304;ASP B 305","  K B 605 ( 3.2A);EDO B 616 (-4.3A);EDO B 616 ( 3.8A);  K B 605 ( 4.8A);EDO B 616 ( 2.8A);  K B 605 ( 4.7A);None;  K B 605 ( 4.7A)","0.99A","1mxdA-5m99B:25.5","1mxdA-5m99B:24.45"],["1TKQ_B_DVAB8_0","GRAMICIDIN A","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"VAL B 207;GLY B 209;VAL B 115;TRP B  70","None","1.25A","1tkqB-5m99B:undetectable","1tkqB-5m99B:4.51"],["1VPT_A_SAMA400_0","VP39","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ILE B  35;VAL B  54;VAL B  69;ALA B  68;LEU B  61","None","1.01A","1vptA-5m99B:undetectable","1vptA-5m99B:21.02"],["1YAT_A_FK5A108_1","FK506 BINDING PROTEIN","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.31A","1yatA-5m99B:undetectable","1yatA-5m99B:14.82"],["2BTE_A_LEUA1894_0","AMINOACYL-TRNA SYNTHETASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"MET B  72;TYR B  80;TYR B  83;HIS B 304","None;None;  K B 605 ( 3.2A);None","1.09A","2bteA-5m99B:undetectable","2bteA-5m99B:20.16"],["2BTE_D_LEUD1893_0","AMINOACYL-TRNA SYNTHETASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"MET B  72;TYR B  80;TYR B  83;HIS B 304","None;None;  K B 605 ( 3.2A);None","1.07A","2bteD-5m99B:2.5","2bteD-5m99B:20.16"],["2BYT_A_LEUA1301_0","LEUCYL-TRNA SYNTHETASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"MET B  72;TYR B  80;TYR B  83;HIS B 304","None;None;  K B 605 ( 3.2A);None","1.11A","2bytA-5m99B:2.2","2bytA-5m99B:20.16"],["2BYT_D_LEUD1601_0","LEUCYL-TRNA SYNTHETASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"MET B  72;TYR B  80;TYR B  83;HIS B 304","None;None;  K B 605 ( 3.2A);None","1.10A","2bytD-5m99B:undetectable","2bytD-5m99B:20.16"],["2KOT_A_ANWA99_0","PROTEIN S100-A13","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"VAL B 474;PHE B 463;THR B 452;LYS B 343","None","0.98A","2kotA-5m99B:undetectable","2kotA-5m99B:11.11"],["2KOT_B_ANWB99_0","PROTEIN S100-A13","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"VAL B 474;PHE B 463;THR B 452;LYS B 343","None","1.15A","2kotB-5m99B:undetectable","2kotB-5m99B:11.11"],["2V0G_A_LEUA1887_0","AMINOACYL-TRNA SYNTHETASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"MET B  72;TYR B  80;TYR B  83;HIS B 304","None;None;  K B 605 ( 3.2A);None","1.15A","2v0gA-5m99B:2.5","2v0gA-5m99B:20.16"],["2VDV_E_SAME1287_0","TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"GLY B  49;GLY B  47;ASN B  52;ASP B  94;THR B 389"," NA B 602 ( 4.8A);None;None;None;None","1.12A","2vdvE-5m99B:undetectable","2vdvE-5m99B:17.13"],["2VDV_F_SAMF1287_0","TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"GLY B  49;GLY B  47;ASN B  52;ASP B  94;THR B 389"," NA B 602 ( 4.8A);None;None;None;None","1.12A","2vdvF-5m99B:undetectable","2vdvF-5m99B:17.13"],["2ZI9_A_CL9A401_1","DEOXYCYTIDINE KINASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"GLU B 253;MET B 275;TYR B 276;PHE B 300;ARG B 211","  K B 605 ( 4.7A);None;None;None;  K B 605 ( 4.8A)","1.06A","2zi9A-5m99B:0.0","2zi9A-5m99B:18.40"],["3AIC_A_ACRA5044_1","GLUCOSYLTRANSFERASE-SI","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"ARG B 211;ASP B 213;ALA B 214;GLU B 253;HIS B 304;ASP B 305","  K B 605 ( 4.8A);EDO B 616 ( 2.8A);EDO B 616 ( 4.7A);  K B 605 ( 4.7A);None;  K B 605 ( 4.7A)","0.64A","3aicA-5m99B:3.3","3aicA-5m99B:21.11"],["3AIC_B_ACRB5044_1","GLUCOSYLTRANSFERASE-SI","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"ARG B 211;ASP B 213;ALA B 214;GLU B 253;HIS B 304;ASP B 305","  K B 605 ( 4.8A);EDO B 616 ( 2.8A);EDO B 616 ( 4.7A);  K B 605 ( 4.7A);None;  K B 605 ( 4.7A)","0.64A","3aicB-5m99B:5.1","3aicB-5m99B:21.11"],["3AIC_C_ACRC5044_1","GLUCOSYLTRANSFERASE-SI","5m99","ALPHA-AMYLASE","Thermotoga petrophila",7,"ARG B 211;ASP B 213;ALA B 214;GLU B 253;HIS B 304;ASP B 305;TYR B  83","  K B 605 ( 4.8A);EDO B 616 ( 2.8A);EDO B 616 ( 4.7A);  K B 605 ( 4.7A);None;  K B 605 ( 4.7A);  K B 605 ( 3.2A)","0.63A","3aicC-5m99B:7.6","3aicC-5m99B:21.11"],["3AIC_D_ACRD5044_1","GLUCOSYLTRANSFERASE-SI","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"ARG B 211;ASP B 213;ALA B 214;GLU B 253;HIS B 304;ASP B 305","  K B 605 ( 4.8A);EDO B 616 ( 2.8A);EDO B 616 ( 4.7A);  K B 605 ( 4.7A);None;  K B 605 ( 4.7A)","0.70A","3aicD-5m99B:4.0","3aicD-5m99B:21.11"],["3AIC_E_ACRE5044_1","GLUCOSYLTRANSFERASE-SI","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"ARG B 211;ASP B 213;ALA B 214;GLU B 253;HIS B 304;ASP B 305","  K B 605 ( 4.8A);EDO B 616 ( 2.8A);EDO B 616 ( 4.7A);  K B 605 ( 4.7A);None;  K B 605 ( 4.7A)","0.68A","3aicE-5m99B:8.0","3aicE-5m99B:21.11"],["3AIC_F_ACRF5044_1","GLUCOSYLTRANSFERASE-SI","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"ARG B 211;ASP B 213;ALA B 214;GLU B 253;HIS B 304;ASP B 305","  K B 605 ( 4.8A);EDO B 616 ( 2.8A);EDO B 616 ( 4.7A);  K B 605 ( 4.7A);None;  K B 605 ( 4.7A)","0.63A","3aicF-5m99B:undetectable","3aicF-5m99B:21.11"],["3AIC_G_ACRG5044_1","GLUCOSYLTRANSFERASE-SI","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"ARG B 211;ASP B 213;ALA B 214;GLU B 253;HIS B 304;ASP B 305","  K B 605 ( 4.8A);EDO B 616 ( 2.8A);EDO B 616 ( 4.7A);  K B 605 ( 4.7A);None;  K B 605 ( 4.7A)","0.62A","3aicG-5m99B:8.0","3aicG-5m99B:21.11"],["3AIC_H_ACRH5044_1","GLUCOSYLTRANSFERASE-SI","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"ARG B 211;ASP B 213;ALA B 214;GLU B 253;HIS B 304;ASP B 305","  K B 605 ( 4.8A);EDO B 616 ( 2.8A);EDO B 616 ( 4.7A);  K B 605 ( 4.7A);None;  K B 605 ( 4.7A)","0.71A","3aicH-5m99B:6.3","3aicH-5m99B:21.11"],["3AXZ_A_ADNA401_1","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"LEU B  40;SER B  39;PRO B 373;GLY B  47;GLY B 384","None","1.09A","3axzA-5m99B:undetectable","3axzA-5m99B:18.61"],["3BXO_A_SAMA238_1","N,N-DIMETHYLTRANSFERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",3,"TYR B 336;GLU B  34;ASP B 213","None;None;EDO B 616 ( 2.8A)","0.64A","3bxoA-5m99B:undetectable","3bxoA-5m99B:18.29"],["3BXO_B_SAMB238_1","N,N-DIMETHYLTRANSFERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",3,"TYR B 336;GLU B  34;ASP B 213","None;None;EDO B 616 ( 2.8A)","0.70A","3bxoB-5m99B:undetectable","3bxoB-5m99B:18.29"],["3KPB_C_SAMC1000_0","UNCHARACTERIZED PROTEIN MJ0100","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"HIS B  81;VAL B 120;ILE B  85;SER B  79;PRO B  73","None","1.01A","3kpbC-5m99B:undetectable","3kpbC-5m99B:12.48"],["3KZ7_A_RAPA225_1","FK506-BINDING PROTEIN 3","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.23A","3kz7A-5m99B:undetectable","3kz7A-5m99B:13.44"],["3NAI_C_URFC521_1","RNA DEPENDENT RNA POLYMERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"ARG B  38;ASP B  42;ASP B  46;ASP B  44","None; NA B 602 (-3.2A); NA B 602 (-2.9A); NA B 602 (-3.1A)","1.48A","3naiC-5m99B:undetectable","3naiC-5m99B:21.25"],["3UGR_A_IMNA2001_2","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"TYR B 349;GLU B 368;TYR B 366;TYR B 393","None","1.26A","3ugrA-5m99B:7.7","3ugrA-5m99B:20.88"],["3VAW_A_FK5A114_1","UBIQUITIN-LIKE PROTEIN SMT3,PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.29A","3vawA-5m99B:undetectable","3vawA-5m99B:18.06"],["3WEO_A_ACRA1001_2","ALPHA-GLUCOSIDASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"ILE B  35;ILE B 203;TRP B 202;MET B 117","None","1.40A","3weoA-5m99B:13.5","3weoA-5m99B:20.35"],["4A97_E_ZPCE1318_2","CYS-LOOP LIGAND-GATED ION CHANNEL","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"GLU B 302;PHE B 310;TYR B 336;PHE B 309","None","1.19A","4a97E-5m99B:undetectable","4a97E-5m99B:21.01"],["4AC9_B_DXCB1473_0","MJ0495-LIKE PROTEIN","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"ILE B 121;ASP B 213;ILE B 212;PHE B 237;VAL B 241;GLY B 209","None;EDO B 616 ( 2.8A);None;None;None;None","1.37A","4ac9B-5m99B:3.3;4ac9C-5m99B:2.1","4ac9B-5m99B:19.38;4ac9C-5m99B:19.38"],["4DRI_A_RAPA201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.22A","4driA-5m99B:undetectable","4driA-5m99B:15.52"],["4DZ2_A_FK5A200_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE;PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.25A","4dz2A-5m99B:undetectable;4dz2B-5m99B:undetectable","4dz2A-5m99B:12.67;4dz2B-5m99B:12.67"],["4DZ2_B_FK5B200_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE;PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.28A","4dz2A-5m99B:undetectable;4dz2B-5m99B:undetectable","4dz2A-5m99B:12.67;4dz2B-5m99B:12.67"],["4DZ3_A_FK5A201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.28A","4dz3A-5m99B:undetectable","4dz3A-5m99B:12.44"],["4DZ3_B_FK5B201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.28A","4dz3B-5m99B:undetectable","4dz3B-5m99B:12.44"],["4E7C_D_ACTD504_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",3,"GLY B 156;SER B 155;TRP B 172","None","0.95A","4e7cD-5m99B:undetectable","4e7cD-5m99B:22.00"],["4FEV_D_KAND301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"ASP B 213;ASP B 367;ASP B 305;GLU B 253","EDO B 616 ( 2.8A);None;  K B 605 ( 4.7A);  K B 605 ( 4.7A)","1.23A","4fevD-5m99B:4.3","4fevD-5m99B:18.98"],["4NNR_A_FK5A201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2;PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.24A","4nnrA-5m99B:undetectable;4nnrB-5m99B:undetectable","4nnrA-5m99B:14.80;4nnrB-5m99B:14.80"],["4NNR_B_FK5B201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.18A","4nnrB-5m99B:undetectable","4nnrB-5m99B:14.80"],["4QT2_A_RAPA202_1","FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.21A","4qt2A-5m99B:undetectable","4qt2A-5m99B:14.85"],["5BPH_B_ACTB404_0","D-ALANINE--D-ALANINE LIGASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"TYR B  60;TYR B  33;GLY B 352;LEU B 430","EDO B 609 (-4.9A);None;None;None","1.12A","5bphB-5m99B:undetectable","5bphB-5m99B:20.59"],["5CSY_B_ACRB601_1","4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC\/AMYLOPLASTIC","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ARG B 211;ASP B 213;GLU B 253;HIS B 304;ASP B 305","  K B 605 ( 4.8A);EDO B 616 ( 2.8A);  K B 605 ( 4.7A);None;  K B 605 ( 4.7A)","0.45A","5csyB-5m99B:18.7","5csyB-5m99B:20.16"],["5DX3_A_ESTA601_1","ESTROGEN RECEPTOR","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"LEU B 338;LEU B 301;MET B 275;HIS B 316;LEU B 313","None","1.38A","5dx3A-5m99B:undetectable","5dx3A-5m99B:19.35"],["5HWC_A_FK5A201_1","FK506-BINDING PROTEIN 1A","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.23A","5hwcA-5m99B:undetectable","5hwcA-5m99B:14.73"],["5HYR_B_ESTB601_1","ESTROGEN RECEPTOR","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"LEU B 338;LEU B 301;MET B 275;HIS B 316;LEU B 313","None","1.41A","5hyrB-5m99B:undetectable","5hyrB-5m99B:19.56"],["5IFU_B_GBMB801_1","PROLINE--TRNA LIGASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"TYR B  33;ILE B 433;TYR B 336;LEU B 429;GLU B 302","None","1.33A","5ifuB-5m99B:undetectable","5ifuB-5m99B:20.15"],["5L6E_A_SAMA601_1","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"ASP B 100;ASN B 111;ASN B 103;GLN B 106","None;EDO B 615 (-3.2A);None;None","1.16A","5l6eA-5m99B:undetectable","5l6eA-5m99B:21.59"],["5NO9_D_95ZD302_1","25 KDA PROTEIN ELICITOR","5m99","ALPHA-AMYLASE","Thermotoga petrophila",4,"GLY B 209;ASP B 247;HIS B 109;ASP B 208","None","1.07A","5no9D-5m99B:undetectable","5no9D-5m99B:10.61"],["5VEU_B_RITB602_1","CYTOCHROME P450 3A5","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"PHE B 454;PHE B 337;PHE B 486;ALA B 445;ILE B 446","None","1.06A","5veuB-5m99B:undetectable","5veuB-5m99B:22.56"],["6AG0_A_ACRA610_0","ALPHA-AMYLASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",7,"TYR B  83;HIS B 123;ASP B 213;LYS B 216;HIS B 217;HIS B 304;ASP B 305","  K B 605 ( 3.2A);EDO B 616 (-4.3A);EDO B 616 ( 2.8A);None; NA B 604 ( 4.9A);None;  K B 605 ( 4.7A)","0.50A","6ag0A-5m99B:22.1","6ag0A-5m99B:10.04"],["6AG0_A_ACRA610_0","ALPHA-AMYLASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"TYR B  83;HIS B 123;MET B 181;ASP B 213;HIS B 304;ASP B 305","  K B 605 ( 3.2A);EDO B 616 (-4.3A);EDO B 616 ( 4.1A);EDO B 616 ( 2.8A);None;  K B 605 ( 4.7A)","0.99A","6ag0A-5m99B:22.1","6ag0A-5m99B:10.04"],["6AG0_C_ACRC608_0","ALPHA-AMYLASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",6,"ASP B 213;LYS B 216;HIS B 217;TYR B 276;HIS B 304;ASP B 305","EDO B 616 ( 2.8A);None; NA B 604 ( 4.9A);None;None;  K B 605 ( 4.7A)","0.85A","6ag0C-5m99B:22.1","6ag0C-5m99B:10.04"],["6CBZ_B_ESTB602_1","ESTROGEN RECEPTOR","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"LEU B 338;LEU B 301;MET B 275;HIS B 316;LEU B 313","None","1.36A","6cbzB-5m99B:undetectable","6cbzB-5m99B:11.00"],["6MKE_C_FK5C201_1","PEPTIDYLPROLYL ISOMERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.25A","6mkeC-5m99B:undetectable","6mkeC-5m99B:10.54"],["6MKE_D_FK5D201_1","PEPTIDYLPROLYL ISOMERASE","5m99","ALPHA-AMYLASE","Thermotoga petrophila",5,"ASP B 213;VAL B 195;ILE B 198;TYR B  88;ILE B  85","EDO B 616 ( 2.8A);None;None;None;None","1.30A","6mkeD-5m99B:undetectable","6mkeD-5m99B:10.54"]]