SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m9n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5m9n TUDOR
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 SER A 567
GLU A 568
GLU A 569
 None
None
EDO  A 701 ( 4.9A)
 0.61A 1eqbD-5m9nA:
undetectable		 1eqbD-5m9nA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5m9n TUDOR
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 SER A 567
GLU A 568
GLU A 569
 None
None
EDO  A 701 ( 4.9A)
 0.59A 1eqbB-5m9nA:
undetectable		 1eqbB-5m9nA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 5m9n TUDOR
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 GLU A 506
LEU A 608
VAL A 662
LEU A 625
 None
 1.00A 1hk3A-5m9nA:
undetectable		 1hk3A-5m9nA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 5m9n TUDOR
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 11 VAL A 573
GLY A 574
ALA A 549
LEU A 584
ARG A 588
 None
EDO  A 702 ( 3.8A)
None
None
None
 1.01A 2bxgA-5m9nA:
undetectable		 2bxgA-5m9nA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5m9n TUDOR
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLN A 512
PHE A 509
ALA A 500
GLY A 497
LEU A 651
 None
EDO  A 702 ( 4.7A)
None
None
None
 1.19A 3aobC-5m9nA:
undetectable		 3aobC-5m9nA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5m9n TUDOR
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLN A 512
PHE A 509
ALA A 500
GLY A 497
LEU A 651
 None
EDO  A 702 ( 4.7A)
None
None
None
 1.37A 3aodC-5m9nA:
undetectable		 3aodC-5m9nA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 5m9n TUDOR
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LEU A 666
GLU A 621
ILE A 623
 None
 0.59A 3czhA-5m9nA:
undetectable		 3czhA-5m9nA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 5m9n TUDOR
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 GLU A 582
ARG A 588
TYR A 575
TYR A 558
 None
 1.15A 4zz8A-5m9nA:
undetectable		 4zz8A-5m9nA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 5m9n TUDOR
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 649
GLN A 512
CYH A 510
 None
 0.83A 5icxC-5m9nA:
undetectable
5icxF-5m9nA:
undetectable		 5icxC-5m9nA:
23.05
5icxF-5m9nA:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5m9n TUDOR
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 5 ARG A 588
ALA A 549
TYR A 558
GLN A 550
 None
 1.20A 6f6sA-5m9nA:
undetectable
6f6sB-5m9nA:
undetectable		 6f6sA-5m9nA:
16.36
6f6sB-5m9nA:
15.81