SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5m9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 11 SER A 834
LEU A 828
VAL A 698
PHE A 696
VAL A 840
 None
 1.36A 1q23F-5m9oA:
undetectable		 1q23F-5m9oA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 11 SER A 834
LEU A 828
VAL A 698
PHE A 696
VAL A 840
 None
 1.40A 1q23I-5m9oA:
undetectable		 1q23I-5m9oA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 SER A 834
LEU A 828
VAL A 698
PHE A 696
VAL A 840
 None
 1.44A 1q23K-5m9oA:
undetectable		 1q23K-5m9oA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 5 GLY A 859
PRO A 804
VAL A 803
ILE A 801
 None
 0.94A 2aoiA-5m9oA:
undetectable		 2aoiA-5m9oA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 LEU A 707
LEU A 710
ILE A 718
TYR A 746
 None
 1.08A 2hc4A-5m9oA:
undetectable		 2hc4A-5m9oA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 GLU A 751
HIS A 695
VAL A 698
PHE A 762
 None
 1.01A 4a97E-5m9oA:
undetectable		 4a97E-5m9oA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 GLU A 751
HIS A 695
VAL A 698
PHE A 762
 None
 1.07A 4a97H-5m9oA:
undetectable		 4a97H-5m9oA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 5 HIS A 760
VAL A 753
GLU A 754
VAL A 771
 None
 1.13A 4p6vB-5m9oA:
undetectable
4p6vE-5m9oA:
undetectable		 4p6vB-5m9oA:
20.72
4p6vE-5m9oA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 GLU A 770
ARG A 776
TYR A 763
TYR A 746
 None
 1.13A 4zz8A-5m9oA:
undetectable		 4zz8A-5m9oA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 856
VAL A 861
GLN A 802
 None
 0.65A 5qgyA-5m9oA:
undetectable		 5qgyA-5m9oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 856
VAL A 861
GLN A 802
 None
 0.65A 5qgzA-5m9oA:
undetectable		 5qgzA-5m9oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 856
VAL A 861
GLN A 802
 None
 0.66A 5qh0A-5m9oA:
undetectable		 5qh0A-5m9oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 856
VAL A 861
GLN A 802
 None
 0.64A 5qh2A-5m9oA:
undetectable		 5qh2A-5m9oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 856
VAL A 861
GLN A 802
 None
 0.65A 5qh3A-5m9oA:
undetectable		 5qh3A-5m9oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 856
VAL A 861
GLN A 802
 None
 0.67A 5qh6A-5m9oA:
undetectable		 5qh6A-5m9oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 856
VAL A 861
GLN A 802
 None
 0.68A 5qh7A-5m9oA:
undetectable		 5qh7A-5m9oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 856
VAL A 861
GLN A 802
 None
 0.67A 5qhaA-5m9oA:
undetectable		 5qhaA-5m9oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGG_A_SAMA504_0
(RADICAL SAM DOMAIN
PROTEIN)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 TYR A 878
PHE A 696
ASN A 829
VAL A 856
VAL A 861
 None
 1.37A 5wggA-5m9oA:
undetectable		 5wggA-5m9oA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 5m9o STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 ARG A 749
GLY A 733
GLU A 734
 None
 0.48A 6fgdA-5m9oA:
undetectable		 6fgdA-5m9oA:
18.68