SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ma6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJL_A_SAMA200_0 (METHIONINE REPRESSOR PROTEIN METJ)	5ma6	3G124NC (synthetic construct)	5 / 11	ALA B 137 HIS B 118 LEU B 126 ALA B 121 LEU B 165	None	1.23A	1mjlA-5ma6B: undetectable 1mjlB-5ma6B: undetectable	1mjlA-5ma6B: undetectable 1mjlB-5ma6B: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AQI_B_CHDB5_0 (FERROCHELATASE)	5ma6	3G124NC (synthetic construct)	3 / 3	PRO B 83 LEU B 86 ARG B 57	None	0.72A	3aqiB-5ma6B: undetectable	3aqiB-5ma6B: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_I_IPHI101_0 (INSULIN)	5ma6	3G124NC (synthetic construct)	5 / 12	VAL B 30 LEU B 18 LEU B 51 ILE B 62 ALA B 71	None None None PO4 B 201 (-4.4A) None	1.00A	4p65B-5ma6B: undetectable 4p65D-5ma6B: undetectable 4p65I-5ma6B: undetectable 4p65J-5ma6B: undetectable	4p65B-5ma6B: undetectable 4p65D-5ma6B: undetectable 4p65I-5ma6B: undetectable 4p65J-5ma6B: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_K_IPHK101_0 (INSULIN)	5ma6	3G124NC (synthetic construct)	5 / 12	LEU B 51 VAL B 30 LEU B 18 ILE B 62 ALA B 71	None None None PO4 B 201 (-4.4A) None	1.05A	4p65F-5ma6B: undetectable 4p65H-5ma6B: undetectable 4p65K-5ma6B: undetectable 4p65L-5ma6B: undetectable	4p65F-5ma6B: undetectable 4p65H-5ma6B: undetectable 4p65K-5ma6B: undetectable 4p65L-5ma6B: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MJL_A_SAMA200_0","METHIONINE REPRESSOR PROTEIN METJ","5ma6","3G124NC","synthetic construct",5,"ALA B 137;HIS B 118;LEU B 126;ALA B 121;LEU B 165","None","1.23A","1mjlA-5ma6B:undetectable;1mjlB-5ma6B:undetectable","1mjlA-5ma6B:undetectable;1mjlB-5ma6B:undetectable"],["3AQI_B_CHDB5_0","FERROCHELATASE","5ma6","3G124NC","synthetic construct",3,"PRO B  83;LEU B  86;ARG B  57","None","0.72A","3aqiB-5ma6B:undetectable","3aqiB-5ma6B:undetectable"],["4P65_I_IPHI101_0","INSULIN","5ma6","3G124NC","synthetic construct",5,"VAL B  30;LEU B  18;LEU B  51;ILE B  62;ALA B  71","None;None;None;PO4 B 201 (-4.4A);None","1.00A","4p65B-5ma6B:undetectable;4p65D-5ma6B:undetectable;4p65I-5ma6B:undetectable;4p65J-5ma6B:undetectable","4p65B-5ma6B:undetectable;4p65D-5ma6B:undetectable;4p65I-5ma6B:undetectable;4p65J-5ma6B:undetectable"],["4P65_K_IPHK101_0","INSULIN","5ma6","3G124NC","synthetic construct",5,"LEU B  51;VAL B  30;LEU B  18;ILE B  62;ALA B  71","None;None;None;PO4 B 201 (-4.4A);None","1.05A","4p65F-5ma6B:undetectable;4p65H-5ma6B:undetectable;4p65K-5ma6B:undetectable;4p65L-5ma6B:undetectable","4p65F-5ma6B:undetectable;4p65H-5ma6B:undetectable;4p65K-5ma6B:undetectable;4p65L-5ma6B:undetectable"]]