SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mau'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 5mau CHLORITE DISMUTASE
(Cyanothece
sp.
PCC
7425) 		4 / 7 HIS A 131
LEU A 129
TYR A  61
ILE A  90
 None
HEM  A 201 ( 4.2A)
HEM  A 201 (-4.7A)
HEM  A 201 ( 3.5A)
 1.06A 1tuvA-5mauA:
5.0		 1tuvA-5mauA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5mau CHLORITE DISMUTASE
(Cyanothece
sp.
PCC
7425) 		5 / 12 SER A 112
SER A 165
VAL A 117
GLY A 118
ALA A 116
 None
None
None
HEM  A 201 (-3.1A)
None
 1.28A 2x2iC-5mauA:
undetectable		 2x2iC-5mauA:
5.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5mau CHLORITE DISMUTASE
(Cyanothece
sp.
PCC
7425) 		5 / 12 GLY A   9
LEU A  28
ASN A  35
ARG A 128
LEU A  87
 None
None
None
GOL  A 204 (-3.7A)
None
 1.38A 5emlA-5mauA:
undetectable		 5emlA-5mauA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5mau CHLORITE DISMUTASE
(Cyanothece
sp.
PCC
7425) 		4 / 6 ASP A 140
ARG A   4
ASN A   3
GLN A  53
 None
SO4  A 202 (-3.4A)
None
None
 1.12A 5l6eA-5mauA:
undetectable		 5l6eA-5mauA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 5mau CHLORITE DISMUTASE
(Cyanothece
sp.
PCC
7425) 		3 / 3 ARG A  51
ILE A   8
SER A   6
 None
 0.62A 5zw2A-5mauA:
undetectable		 5zw2A-5mauA:
undetectable