SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5maw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5maw FLAGELLAR PROTEIN
FLIS
(Bacillus
subtilis) 		5 / 12 ILE E  35
ALA E  38
ALA E  39
LEU E  54
VAL E 108
 None
 1.04A 1fbyA-5mawE:
undetectable		 1fbyA-5mawE:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5maw FLAGELLAR PROTEIN
FLIS
(Bacillus
subtilis) 		5 / 12 ILE E  35
ALA E  38
ALA E  39
LEU E  54
VAL E 108
 None
 1.03A 1fbyB-5mawE:
undetectable		 1fbyB-5mawE:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5maw FLAGELLAR PROTEIN
FLIS
(Bacillus
subtilis) 		5 / 12 ILE E  35
ALA E  38
ALA E  39
LEU E  54
VAL E 108
 None
 0.96A 1fm6A-5mawE:
undetectable		 1fm6A-5mawE:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5maw FLAGELLAR PROTEIN
FLIS
(Bacillus
subtilis) 		5 / 10 ILE E  35
ALA E  39
ALA E  38
GLN E  40
ILE E  60
 None
 1.08A 2aclC-5mawE:
undetectable		 2aclC-5mawE:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5maw FLAGELLAR PROTEIN
FLIS
(Bacillus
subtilis) 		5 / 11 ILE E  35
ALA E  39
ALA E  38
GLN E  40
ILE E  60
 None
 1.11A 2aclE-5mawE:
undetectable		 2aclE-5mawE:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 5maw FLAGELLAR PROTEIN
FLIS
(Bacillus
subtilis) 		4 / 8 TYR E  86
VAL E  90
ASN E  59
ILE E  55
 None
 0.80A 6hzpA-5mawE:
4.3		 6hzpA-5mawE:
undetectable