SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mb4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O01_B_DXCB1_0
(CELL INVASION
PROTEIN SIPD)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		5 / 9 ILE A 139
PHE A 195
ALA A 161
LEU A 155
ASN A 158
 None
NAG  A 508 ( 4.7A)
None
None
None
 1.27A 3o01A-5mb4A:
undetectable
3o01B-5mb4A:
undetectable		 3o01A-5mb4A:
22.51
3o01B-5mb4A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		5 / 10 ILE A 139
PHE A 195
ALA A 161
LEU A 155
ASN A 158
 None
NAG  A 508 ( 4.7A)
None
None
None
 1.23A 3o02A-5mb4A:
undetectable
3o02B-5mb4A:
undetectable		 3o02A-5mb4A:
22.51
3o02B-5mb4A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		4 / 5 ILE A  15
PRO A  16
SER A 291
GLY A 348
 None
 1.19A 3tkdB-5mb4A:
undetectable		 3tkdB-5mb4A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 GLY A 356
THR A 382
ASN A 358
 NAG  A 513 (-3.4A)
None
None
 0.72A 3v4tD-5mb4A:
undetectable		 3v4tD-5mb4A:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 ASP A  69
ARG A  33
THR A  67
 NA  A 505 ( 3.0A)
None
NA  A 505 (-2.9A)
 0.88A 4i13A-5mb4A:
undetectable		 4i13A-5mb4A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 GLU A 191
ARG A 170
HIS A 171
 None
MLI  A 507 (-3.8A)
NDG  A 509 ( 3.9A)
 0.85A 4kf9A-5mb4A:
undetectable		 4kf9A-5mb4A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		4 / 5 VAL A 267
LEU A 243
VAL A 286
PHE A 316
 None
 0.96A 4lb0B-5mb4A:
undetectable		 4lb0B-5mb4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		5 / 11 MET A 123
LEU A 175
ARG A 173
VAL A  82
TRP A 111
 None
None
None
None
NAG  A 514 ( 3.6A)
 1.33A 4mk4B-5mb4A:
undetectable		 4mk4B-5mb4A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 ASP A  69
ARG A  33
THR A  67
 NA  A 505 ( 3.0A)
None
NA  A 505 (-2.9A)
 0.87A 4p3rA-5mb4A:
undetectable		 4p3rA-5mb4A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		4 / 5 ALA A 156
HIS A  99
PRO A 152
PHE A 104
 None
 1.34A 4ze2A-5mb4A:
undetectable		 4ze2A-5mb4A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		4 / 7 THR A  67
ASP A  69
ASP A  73
GLY A  89
 NA  A 505 (-2.9A)
NA  A 505 ( 3.0A)
NA  A 505 (-2.9A)
NA  A 506 ( 4.7A)
 1.02A 5hwaA-5mb4A:
undetectable		 5hwaA-5mb4A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 LYS A 376
ASP A 374
ILE A  32
 None
 0.62A 5kc4E-5mb4A:
undetectable		 5kc4E-5mb4A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 LYS A   3
GLN A  71
ASN A  70
 None
NA  A 506 ( 3.1A)
None
 1.01A 5l2tA-5mb4A:
undetectable		 5l2tA-5mb4A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		5 / 12 PHE A 215
TRP A 222
GLY A 218
GLY A 190
VAL A 194
 None
NAG  A 512 (-3.5A)
None
NDG  A 509 ( 3.4A)
None
 1.20A 5o4yD-5mb4A:
undetectable
5o4yE-5mb4A:
undetectable		 5o4yD-5mb4A:
4.40
5o4yE-5mb4A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		5 / 12 LEU A 377
ALA A 396
THR A  13
ALA A 350
GLY A 346
 None
 1.05A 5veuA-5mb4A:
undetectable		 5veuA-5mb4A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		5 / 12 LEU A 377
ALA A 396
THR A  13
ALA A 350
GLY A 346
 None
 0.93A 5veuB-5mb4A:
undetectable		 5veuB-5mb4A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		5 / 12 GLY A 295
SER A   6
LEU A 172
ILE A 231
ASP A 241
 None
None
None
None
NA  A 503 (-2.7A)
 1.20A 6bxmA-5mb4A:
undetectable		 6bxmA-5mb4A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 ARG A  55
HIS A  59
ARG A  61
 None
NAG  A 510 ( 3.6A)
None
 1.13A 6dwdD-5mb4A:
undetectable		 6dwdD-5mb4A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 ARG A 112
HIS A 116
ARG A 118
 None
NDG  A 515 ( 3.9A)
NA  A 502 (-3.3A)
 1.09A 6dwdD-5mb4A:
undetectable		 6dwdD-5mb4A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 ARG A 167
HIS A 171
ARG A 173
 None
NDG  A 509 ( 3.9A)
None
 1.15A 6dwdD-5mb4A:
undetectable		 6dwdD-5mb4A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 ARG A 278
HIS A 282
ARG A 284
 None
NAG  A 511 (-4.1A)
None
 1.08A 6dwdD-5mb4A:
undetectable		 6dwdD-5mb4A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 ARG A 333
HIS A 337
ARG A 339
 None
NAG  A 513 ( 3.9A)
None
 1.16A 6dwdD-5mb4A:
undetectable		 6dwdD-5mb4A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 5mb4 GLCNAC SPECIFIC
LECTIN
(Psathyrella) 		3 / 3 SER A   6
SER A   9
ALA A 287
 None
 0.48A 6dwnC-5mb4A:
undetectable		 6dwnC-5mb4A:
10.89