SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mbh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5mbh BETA SUBUNIT OF
PHOTOACTIVATED
ADENYLYL CYCLASE
(Beggiatoa
sp.
PS) 		5 / 12 SER A 249
PHE A 154
THR A 293
ILE A 216
SER A 219
 None
 1.26A 2fj1A-5mbhA:
undetectable		 2fj1A-5mbhA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TCT_A_CTCA222_0
(TETRACYCLINE
REPRESSOR)		 5mbh BETA SUBUNIT OF
PHOTOACTIVATED
ADENYLYL CYCLASE
(Beggiatoa
sp.
PS) 		5 / 12 SER A 249
PHE A 154
THR A 293
ILE A 216
SER A 219
 None
 1.33A 2tctA-5mbhA:
undetectable		 2tctA-5mbhA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5mbh BETA SUBUNIT OF
PHOTOACTIVATED
ADENYLYL CYCLASE
(Beggiatoa
sp.
PS) 		5 / 10 ILE A 188
PHE A 292
ALA A 329
LEU A 290
ALA A 291
 None
 1.29A 3lw5B-5mbhA:
undetectable		 3lw5B-5mbhA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 5mbh BETA SUBUNIT OF
PHOTOACTIVATED
ADENYLYL CYCLASE
(Beggiatoa
sp.
PS) 		4 / 7 GLU A 124
LEU A  77
ARG A 121
THR A 117
 None
 1.31A 3mbgA-5mbhA:
undetectable
3mbgB-5mbhA:
undetectable		 3mbgA-5mbhA:
15.91
3mbgB-5mbhA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2G_B_CTCB222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5mbh BETA SUBUNIT OF
PHOTOACTIVATED
ADENYLYL CYCLASE
(Beggiatoa
sp.
PS) 		5 / 12 SER A 249
PHE A 154
THR A 293
ILE A 216
SER A 219
 None
 1.28A 4v2gB-5mbhA:
1.4		 4v2gB-5mbhA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5mbh BETA SUBUNIT OF
PHOTOACTIVATED
ADENYLYL CYCLASE
(Beggiatoa
sp.
PS) 		4 / 6 ILE A 199
VAL A 195
PHE A 155
ARG A 278
 None
 1.14A 4xe5A-5mbhA:
undetectable		 4xe5A-5mbhA:
15.71