SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mbm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 5mbm DARPIN 8H6
(synthetic
construct) 		3 / 3 SER C  75
HIS C 117
ASP C 137
 None
 0.81A 2wa2B-5mbmC:
undetectable		 2wa2B-5mbmC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5mbm DARPIN 8H6
(synthetic
construct) 		5 / 12 ILE C 160
VAL C  95
ILE C 127
GLU C  96
GLU C  93
 None
 1.33A 4i41A-5mbmC:
undetectable		 4i41A-5mbmC:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 5mbm DARPIN 8H6
(synthetic
construct) 		6 / 12 LEU C  83
VAL C  62
LEU C  51
ILE C  94
LEU C  99
ALA C 103
 None
 1.33A 4p65F-5mbmC:
undetectable
4p65H-5mbmC:
undetectable
4p65K-5mbmC:
undetectable
4p65L-5mbmC:
undetectable		 4p65F-5mbmC:
undetectable
4p65H-5mbmC:
undetectable
4p65K-5mbmC:
undetectable
4p65L-5mbmC:
undetectable