SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIJ_B_NOVB444_2 (DNA GYRASE SUBUNIT B)	5mc7	COATOMER SUBUNIT ZETA-1 (Homo sapiens)	3 / 3	ASP A 74 PHE A 77 VAL A 109	None	0.76A	1kijB-5mc7A: undetectable	1kijB-5mc7A: 16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XVA_B_ACTB294_0 (GLYCINE N-METHYLTRANSFERASE)	5mc7	COATOMER SUBUNIT ZETA-1 (Homo sapiens)	4 / 6	ALA A 60 GLU A 58 TYR A 78 LEU A 62	None	0.99A	1xvaA-5mc7A: undetectable 1xvaB-5mc7A: undetectable	1xvaA-5mc7A: 20.48 1xvaB-5mc7A: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_C_VIVC301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	5mc7	COATOMER SUBUNIT ZETA-1 (Homo sapiens)	5 / 12	TYR A 31 LEU A 94 ALA A 124 ILE A 18 LEU A 101	None	1.18A	3w67C-5mc7A: undetectable	3w67C-5mc7A: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LMN_A_EUIA503_1 (DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1)	5mc7	COATOMER SUBUNIT ZETA-1 (Homo sapiens)	5 / 12	LEU A 114 ILE A 18 PHE A 122 GLY A 120 LEU A 101	None	1.03A	4lmnA-5mc7A: undetectable	4lmnA-5mc7A: 19.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KIJ_B_NOVB444_2","DNA GYRASE SUBUNIT B","5mc7","COATOMER SUBUNIT ZETA-1","Homo sapiens",3,"ASP A  74;PHE A  77;VAL A 109","None","0.76A","1kijB-5mc7A:undetectable","1kijB-5mc7A:16.93"],["1XVA_B_ACTB294_0","GLYCINE N-METHYLTRANSFERASE","5mc7","COATOMER SUBUNIT ZETA-1","Homo sapiens",4,"ALA A  60;GLU A  58;TYR A  78;LEU A  62","None","0.99A","1xvaA-5mc7A:undetectable;1xvaB-5mc7A:undetectable","1xvaA-5mc7A:20.48;1xvaB-5mc7A:20.48"],["3W67_C_VIVC301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","5mc7","COATOMER SUBUNIT ZETA-1","Homo sapiens",5,"TYR A  31;LEU A  94;ALA A 124;ILE A  18;LEU A 101","None","1.18A","3w67C-5mc7A:undetectable","3w67C-5mc7A:21.40"],["4LMN_A_EUIA503_1","DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1","5mc7","COATOMER SUBUNIT ZETA-1","Homo sapiens",5,"LEU A 114;ILE A  18;PHE A 122;GLY A 120;LEU A 101","None","1.03A","4lmnA-5mc7A:undetectable","4lmnA-5mc7A:19.57"]]