SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		5 / 12 PHE A2318
VAL A2444
ILE A2339
SER A2314
LEU A2478
 None
 1.26A 1fm4A-5mc9A:
undetectable		 1fm4A-5mc9A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 4 ILE A2337
LEU A2478
VAL A2444
ILE A2442
 None
 0.86A 1fm6D-5mc9A:
undetectable		 1fm6D-5mc9A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 5mc9 LAMININ SUBUNIT
ALPHA-1
LAMININ SUBUNIT
BETA-1
(Mus
musculus) 		4 / 6 SER B1783
THR B1784
LEU A2478
ASP A2477
 None
 1.38A 1mxdA-5mc9B:
undetectable		 1mxdA-5mc9B:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 5mc9 LAMININ SUBUNIT
ALPHA-1
LAMININ SUBUNIT
BETA-1
(Mus
musculus;
Mus
musculus) 		5 / 10 LEU B1764
GLU B1760
LEU B1761
ILE A2110
LEU A2103
 None
 1.17A 1wopA-5mc9B:
undetectable		 1wopA-5mc9B:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		5 / 9 THR A2343
LEU A2366
VAL A2371
THR A2386
VAL A2411
 None
 1.35A 2l8mA-5mc9A:
undetectable		 2l8mA-5mc9A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 5mc9 LAMININ SUBUNIT
BETA-1
LAMININ SUBUNIT
GAMMA-1
(Mus
musculus) 		3 / 3 GLU B1767
HIS C1585
GLU C1588
 None
 0.38A 2x45B-5mc9B:
undetectable		 2x45B-5mc9B:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 5mc9 LAMININ SUBUNIT
BETA-1
LAMININ SUBUNIT
GAMMA-1
(Mus
musculus) 		3 / 3 GLU B1767
HIS C1585
GLU C1588
 None
 0.39A 2x45C-5mc9B:
undetectable		 2x45C-5mc9B:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 6 SER A2567
ARG A2574
PRO A2618
GLY A2617
 None
 1.12A 2y7pA-5mc9A:
undetectable		 2y7pA-5mc9A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		3 / 3 THR A2571
SER A2572
ARG A2574
 None
 0.52A 3phnA-5mc9A:
undetectable		 3phnA-5mc9A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 7 LEU A2292
ILE A2212
VAL A2177
LEU A2163
 None
 0.69A 3r9vA-5mc9A:
undetectable
3r9vB-5mc9A:
undetectable		 3r9vA-5mc9A:
18.79
3r9vB-5mc9A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 7 PHE A2318
ALA A2324
ILE A2442
LEU A2469
 None
 1.07A 4uymB-5mc9A:
undetectable		 4uymB-5mc9A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		5 / 10 GLY A2446
TYR A2443
ALA A2354
LEU A2447
LEU A2349
 None
 0.94A 4xj7A-5mc9A:
undetectable
4xj7B-5mc9A:
undetectable		 4xj7A-5mc9A:
16.51
4xj7B-5mc9A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		5 / 12 ILE A2466
LEU A2479
VAL A2326
LEU A2350
PHE A2318
 None
 1.31A 5bykA-5mc9A:
undetectable		 5bykA-5mc9A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		3 / 3 ASN A2468
SER A2314
SER A2315
 None
 0.61A 5gsnA-5mc9A:
undetectable		 5gsnA-5mc9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		5 / 10 ILE A2632
GLY A2652
PHE A2499
GLY A2634
VAL A2497
 None
 1.18A 5i6xA-5mc9A:
undetectable		 5i6xA-5mc9A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 7 LEU A2382
ILE A2398
LYS A2372
VAL A2373
 None
 1.18A 5jh7C-5mc9A:
undetectable		 5jh7C-5mc9A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 7 PHE A2217
SER A2517
ILE A2214
ASN A2286
 None
 1.03A 5n5dA-5mc9A:
undetectable		 5n5dA-5mc9A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		5 / 12 ILE A2466
LEU A2479
VAL A2326
LEU A2350
PHE A2318
 None
 1.31A 5tiwA-5mc9A:
undetectable		 5tiwA-5mc9A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5mc9 LAMININ SUBUNIT
BETA-1
LAMININ SUBUNIT
GAMMA-1
(Mus
musculus;
Mus
musculus) 		3 / 3 GLN C1566
TYR B1747
ASN B1750
 None
 1.06A 6dwdC-5mc9C:
undetectable		 6dwdC-5mc9C:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 5 VAL A2225
PHE A2257
MET A2256
GLY A2167
 None
 1.11A 6hd4A-5mc9A:
undetectable		 6hd4A-5mc9A:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5mc9 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 6 VAL A2225
PHE A2257
MET A2256
GLY A2167
 None
 1.07A 6hd4B-5mc9A:
undetectable		 6hd4B-5mc9A:
9.49