SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mdj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5mdj HOXK
UPTAKE HYDROGENASE
SMALL SUBUNIT
(Cupriavidus
necator) 		4 / 5 GLU S  22
THR S  18
HIS S  13
LEU S  48
 None
 1.21A 1d4fC-5mdjS:
3.3		 1d4fC-5mdjS:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 5mdj HOXK
UPTAKE HYDROGENASE
SMALL SUBUNIT
(Cupriavidus
necator) 		3 / 3 PHE S  24
TRP S  11
GLU S  76
 None
None
F4S  S1003 (-4.1A)
 1.19A 1mogA-5mdjS:
undetectable		 1mogA-5mdjS:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 5mdj HOXK
UPTAKE HYDROGENASE
SMALL SUBUNIT
(Cupriavidus
necator) 		5 / 12 ILE S  90
LEU S  73
TYR S  71
LEU S  10
LEU S  60
 None
 1.21A 2bxfA-5mdjS:
undetectable		 2bxfA-5mdjS:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 5mdj UPTAKE HYDROGENASE
SMALL SUBUNIT
HOXK
(Cupriavidus
necator) 		4 / 5 ALA S 116
GLU S  76
ALA S  74
MET S 156
 None
F4S  S1003 (-4.1A)
None
None
 1.48A 3r9tC-5mdjS:
undetectable		 3r9tC-5mdjS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 5mdj HOXK
UPTAKE HYDROGENASE
SMALL SUBUNIT
(Cupriavidus
necator) 		5 / 12 ASP S 188
HIS S 187
PRO S 224
PHE S 196
TYR S 217
 None
SF4  S1001 (-3.2A)
SF4  S1001 ( 4.5A)
None
None
 1.45A 5ef8A-5mdjS:
undetectable		 5ef8A-5mdjS:
12.74