SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mdm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		4 / 7 GLY E 200
TYR E 191
LEU E 252
ALA E 199
 None
 0.72A 1dmaA-5mdmE:
undetectable		 1dmaA-5mdmE:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		4 / 7 GLN E 245
GLU E  39
PHE E 230
ALA E 198
 None
 1.12A 1linA-5mdmE:
undetectable		 1linA-5mdmE:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		5 / 12 GLN E 245
THR E 217
ILE E 228
PHE E 253
LEU E 252
 None
 1.48A 1m2zD-5mdmE:
undetectable		 1m2zD-5mdmE:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		5 / 12 ALA E  49
TYR E 222
VAL E 262
SER E 264
GLY E 179
 None
 1.39A 2dcfA-5mdmE:
undetectable		 2dcfA-5mdmE:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		4 / 6 LEU E 266
GLU E 234
ASN E 232
SER E 404
 None
 1.43A 3i9jB-5mdmE:
undetectable		 3i9jB-5mdmE:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		4 / 6 SER E  43
PHE E  41
PHE E 230
HIS E 209
 None
 1.20A 3lskD-5mdmE:
undetectable		 3lskD-5mdmE:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		4 / 6 PRO E 111
SER E 118
THR E  67
THR E  66
 None
 1.10A 3tneA-5mdmE:
undetectable		 3tneA-5mdmE:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1000_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		4 / 6 LYS E 379
PRO E 346
LYS E 344
GLU E 345
 None
 1.36A 4a7tA-5mdmE:
undetectable		 4a7tA-5mdmE:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7U_A_ALEA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		4 / 6 LYS E 379
PRO E 346
LYS E 344
GLU E 345
 None
 1.28A 4a7uA-5mdmE:
undetectable		 4a7uA-5mdmE:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		5 / 12 ILE E 360
LEU E 400
GLY E 392
ILE E 391
ASN E 375
 None
 1.14A 4o1eA-5mdmE:
undetectable		 4o1eA-5mdmE:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		5 / 12 ILE E 360
LEU E 400
GLY E 392
ILE E 391
ASN E 375
 None
 1.15A 4o1eB-5mdmE:
undetectable		 4o1eB-5mdmE:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 5mdm GLYCOPROTEIN
(Chandipura
vesiculovirus) 		5 / 12 GLN E 172
ALA E 170
ILE E 177
VAL E 134
PHE E 148
 None
 1.32A 5vlmG-5mdmE:
undetectable		 5vlmG-5mdmE:
18.14