SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mdq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		4 / 4 ARG A 330
ALA A 211
ALA A 246
GLU A 252
 None
 0.93A 1e7bA-5mdqA:
undetectable		 1e7bA-5mdqA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		4 / 4 ARG A 330
ALA A 211
ALA A 246
GLU A 252
 None
 0.89A 1e7bB-5mdqA:
undetectable		 1e7bB-5mdqA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		5 / 11 LEU A 114
GLU A 119
TYR A 118
GLY A 224
ARG A 154
 None
 1.41A 1l5rA-5mdqA:
undetectable		 1l5rA-5mdqA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		5 / 9 ASN A 248
LEU A 325
GLY A 324
TRP A 216
GLY A 141
 None
 1.50A 1ru9H-5mdqA:
undetectable
1ru9L-5mdqA:
undetectable		 1ru9H-5mdqA:
undetectable
1ru9L-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		5 / 10 ASN A 248
LEU A 325
GLY A 324
TRP A 216
GLY A 141
 None
 1.46A 1ruaH-5mdqA:
undetectable
1ruaL-5mdqA:
undetectable		 1ruaH-5mdqA:
undetectable
1ruaL-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		5 / 9 ASN A 248
LEU A 325
GLY A 324
TRP A 216
GLY A 141
 None
 1.45A 1rulH-5mdqA:
undetectable
1rulL-5mdqA:
undetectable		 1rulH-5mdqA:
undetectable
1rulL-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUP_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		5 / 9 ASN A 248
LEU A 325
GLY A 324
TRP A 216
GLY A 141
 None
 1.49A 1rupH-5mdqA:
undetectable
1rupL-5mdqA:
undetectable		 1rupH-5mdqA:
undetectable
1rupL-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		4 / 5 ASN A 127
ASP A 135
GLU A 204
THR A 115
 None
 1.11A 3p2kC-5mdqA:
undetectable		 3p2kC-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_1
(16S RRNA METHYLASE)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		4 / 4 ASN A 127
ASP A 135
GLU A 204
THR A 115
 None
 1.14A 3p2kD-5mdqA:
undetectable		 3p2kD-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		3 / 3 ARG A 154
ASP A 200
GLN A 226
 None
 0.84A 4azsA-5mdqA:
undetectable		 4azsA-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		3 / 3 ASP A 135
TYR A 118
TRP A 136
 None
 0.95A 4p7nA-5mdqA:
undetectable		 4p7nA-5mdqA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		3 / 3 MET A  48
GLN A  49
ARG A  32
 None
 1.01A 5ewzB-5mdqA:
undetectable		 5ewzB-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		3 / 3 TRP A 185
GLU A 204
ASP A 147
 None
None
NA  A 401 ( 4.7A)
 1.02A 5gqbA-5mdqA:
undetectable		 5gqbA-5mdqA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		4 / 6 ILE A 153
GLY A 205
ASN A 206
TRP A 185
 None
 0.92A 5j4nB-5mdqA:
undetectable		 5j4nB-5mdqA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		3 / 3 GLY A 131
ASP A 132
ASN A 336
 None
 0.61A 5jglA-5mdqA:
undetectable		 5jglA-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		3 / 3 MET A  48
GLN A  49
ARG A  32
 None
 0.96A 5m35B-5mdqA:
undetectable		 5m35B-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		3 / 3 MET A  48
GLN A  49
ARG A  32
 None
 0.95A 5m36A-5mdqA:
undetectable		 5m36A-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		3 / 3 MET A  48
GLN A  49
ARG A  32
 None
 0.97A 6fn9A-5mdqA:
undetectable		 6fn9A-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		3 / 3 MET A  48
GLN A  49
ARG A  32
 None
 1.01A 6fnaB-5mdqA:
undetectable		 6fnaB-5mdqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5mdq CHITOPORIN
(Vibrio
harveyi) 		3 / 3 MET A  48
GLN A  49
ARG A  32
 None
 0.96A 6fnbA-5mdqA:
undetectable		 6fnbA-5mdqA:
undetectable