SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mdu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OKC_B_SAMB500_1 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	5mdu	RPB7-BINDING PROTEIN SEB1 (Schizosaccharomy ces pombe)	4 / 6	THR A 500 THR A 505 THR A 515 ASP A 527	None	1.16A	2okcB-5mduA: undetectable	2okcB-5mduA: 14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QE6_A_SAMA400_1 (UNCHARACTERIZED PROTEIN TFU_2867)	5mdu	RPB7-BINDING PROTEIN SEB1 (Schizosaccharomy ces pombe)	3 / 3	ASN A 463 ARG A 472 ASP A 468	None NA A 603 (-4.3A) None	0.97A	2qe6A-5mduA: undetectable	2qe6A-5mduA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QE6_B_SAMB400_1 (UNCHARACTERIZED PROTEIN TFU_2867)	5mdu	RPB7-BINDING PROTEIN SEB1 (Schizosaccharomy ces pombe)	3 / 3	ASN A 463 ARG A 472 ASP A 468	None NA A 603 (-4.3A) None	1.00A	2qe6B-5mduA: undetectable	2qe6B-5mduA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP3_B_AICB2002_1 (TRANSCRIPTIONAL REGULATOR TCAR)	5mdu	RPB7-BINDING PROTEIN SEB1 (Schizosaccharomy ces pombe)	3 / 3	ALA A 453 ARG A 450 LYS A 387	CL A 601 ( 4.4A) None None	1.02A	3kp3B-5mduA: undetectable	3kp3B-5mduA: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G5G_B_ACTB1321_0 (PUTATIVE XANTHINE DEHYDROGENASE YAGR MOLYBDENUM-BINDING SU SUBUNIT)	5mdu	RPB7-BINDING PROTEIN SEB1 (Schizosaccharomy ces pombe)	3 / 3	THR A 500 ASP A 501 ALA A 502	None	0.00A	5g5gB-5mduA: undetectable	5g5gB-5mduA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GTQ_B_ACTB207_0 (DUF1778 DOMAIN-CONTAINING PROTEIN N-ACETYLTRANSFERASE)	5mdu	RPB7-BINDING PROTEIN SEB1 (Schizosaccharomy ces pombe)	4 / 6	THR A 414 GLY A 412 ARG A 442 ARG A 472	None NA A 603 ( 3.9A) NA A 603 (-3.7A) NA A 603 (-4.3A)	1.39A	6gtqB-5mduA: undetectable 6gtqD-5mduA: undetectable	6gtqB-5mduA: 22.22 6gtqD-5mduA: 13.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OKC_B_SAMB500_1","TYPE I RESTRICTION ENZYME STYSJI M PROTEIN","5mdu","RPB7-BINDING PROTEIN SEB1","Schizosaccharomyces pombe",4,"THR A 500;THR A 505;THR A 515;ASP A 527","None","1.16A","2okcB-5mduA:undetectable","2okcB-5mduA:14.90"],["2QE6_A_SAMA400_1","UNCHARACTERIZED PROTEIN TFU_2867","5mdu","RPB7-BINDING PROTEIN SEB1","Schizosaccharomyces pombe",3,"ASN A 463;ARG A 472;ASP A 468","None; NA A 603 (-4.3A);None","0.97A","2qe6A-5mduA:undetectable","2qe6A-5mduA:21.53"],["2QE6_B_SAMB400_1","UNCHARACTERIZED PROTEIN TFU_2867","5mdu","RPB7-BINDING PROTEIN SEB1","Schizosaccharomyces pombe",3,"ASN A 463;ARG A 472;ASP A 468","None; NA A 603 (-4.3A);None","1.00A","2qe6B-5mduA:undetectable","2qe6B-5mduA:21.53"],["3KP3_B_AICB2002_1","TRANSCRIPTIONAL REGULATOR TCAR","5mdu","RPB7-BINDING PROTEIN SEB1","Schizosaccharomyces pombe",3,"ALA A 453;ARG A 450;LYS A 387"," CL A 601 ( 4.4A);None;None","1.02A","3kp3B-5mduA:undetectable","3kp3B-5mduA:21.14"],["5G5G_B_ACTB1321_0","PUTATIVE XANTHINE DEHYDROGENASE YAGR MOLYBDENUM-BINDING SU SUBUNIT","5mdu","RPB7-BINDING PROTEIN SEB1","Schizosaccharomyces pombe",3,"THR A 500;ASP A 501;ALA A 502","None","0.00A","5g5gB-5mduA:undetectable","5g5gB-5mduA:18.57"],["6GTQ_B_ACTB207_0","DUF1778 DOMAIN-CONTAINING PROTEIN;N-ACETYLTRANSFERASE","5mdu","RPB7-BINDING PROTEIN SEB1","Schizosaccharomyces pombe",4,"THR A 414;GLY A 412;ARG A 442;ARG A 472","None; NA A 603 ( 3.9A); NA A 603 (-3.7A); NA A 603 (-4.3A)","1.39A","6gtqB-5mduA:undetectable;6gtqD-5mduA:undetectable","6gtqB-5mduA:22.22;6gtqD-5mduA:13.16"]]