SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5me3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 7 ILE A 884
PHE A 865
PHE A 862
PHE A 921
None
1.05A 1e71M-5me3A:
undetectable
1e71M-5me3A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 7 ILE A 884
PHE A 865
PHE A 862
PHE A 921
None
1.04A 1e72M-5me3A:
undetectable
1e72M-5me3A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
3 / 3 MET A 919
LEU A 922
SER A 923
None
0.64A 1ee2A-5me3A:
undetectable
1ee2A-5me3A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 8 SER A1253
ASP A1209
ASN A1211
LEU A1241
None
1.10A 1lhvA-5me3A:
undetectable
1lhvA-5me3A:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 8 ILE A 486
LEU A 490
PHE A 504
GLY A 555
None
0.79A 1os6A-5me3A:
undetectable
1os6A-5me3A:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 TYR A1248
LEU A1241
VAL A1238
SER A1253
LEU A1198
None
1.41A 1rk3A-5me3A:
undetectable
1rk3A-5me3A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 LEU A1049
LEU A1052
ALA A1053
LEU A1023
ILE A1098
None
1.07A 1s9pC-5me3A:
undetectable
1s9pC-5me3A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 4 LEU A 976
LEU A1001
SER A1002
LEU A 984
None
1.15A 1ya3A-5me3A:
2.3
1ya3A-5me3A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 LEU A 801
LEU A 852
ALA A 849
ILE A 848
ALA A 794
None
1.10A 2bxpA-5me3A:
undetectable
2bxpA-5me3A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 MET A 719
LEU A 535
GLY A 560
SER A 561
ILE A 563
None
1.26A 2e7fA-5me3A:
undetectable
2e7fA-5me3A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 9 LEU A1345
ILE A1453
PHE A1291
VAL A1399
THR A1400
None
1.03A 2m9qA-5me3A:
undetectable
2m9qA-5me3A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 11 SER A 437
LEU A 517
ILE A 433
ARG A 529
LEU A 527
None
1.38A 2v0mA-5me3A:
0.0
2v0mA-5me3A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
3 / 3 GLU A 813
GLN A 781
ARG A 822
None
0.94A 2w3bB-5me3A:
undetectable
2w3bB-5me3A:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 7 LEU A 958
GLU A 994
ILE A 983
ALA A1020
None
0.85A 2xkwA-5me3A:
undetectable
2xkwA-5me3A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 ILE A 744
CYH A 708
ARG A 707
LEU A 553
ILE A 706
None
1.18A 2xkwB-5me3A:
undetectable
2xkwB-5me3A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 LEU A1359
ILE A1351
LEU A1298
VAL A1366
PHE A1324
None
1.12A 2ygpA-5me3A:
undetectable
2ygpA-5me3A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 TYR A1248
LEU A1241
VAL A1238
SER A1253
LEU A1198
None
1.41A 2zlcA-5me3A:
undetectable
2zlcA-5me3A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
3 / 3 MET A1411
VAL A1366
GLU A1406
None
0.90A 3c6gA-5me3A:
undetectable
3c6gA-5me3A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 VAL A1082
ARG A1058
ILE A1109
ILE A1098
ALA A1033
None
1.16A 3ohtA-5me3A:
2.9
3ohtB-5me3A:
2.8
3ohtA-5me3A:
17.18
3ohtB-5me3A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 8 ILE A 486
LEU A 490
PHE A 504
GLY A 555
None
0.81A 3selX-5me3A:
undetectable
3selX-5me3A:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 6 ILE A 486
LEU A 490
PHE A 504
GLY A 555
None
0.79A 3sj1X-5me3A:
undetectable
3sj1X-5me3A:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
3 / 3 HIS A1292
HIS A1346
ILE A1342
None
0.75A 3u52A-5me3A:
undetectable
3u52C-5me3A:
undetectable
3u52A-5me3A:
17.29
3u52C-5me3A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 10 TYR A 795
ILE A 800
VAL A 796
TYR A 758
ILE A 782
None
1.42A 3uprA-5me3A:
undetectable
3uprA-5me3A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 10 TYR A 795
ILE A 800
VAL A 796
TYR A 758
ILE A 782
None
1.38A 3uprC-5me3A:
undetectable
3uprC-5me3A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 TYR A1248
LEU A1241
VAL A1238
SER A1253
LEU A1198
None
1.41A 3vt3A-5me3A:
undetectable
3vt3A-5me3A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 TYR A1248
LEU A1241
VAL A1238
SER A1253
LEU A1198
None
1.37A 3vt7A-5me3A:
undetectable
3vt7A-5me3A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
3 / 3 LYS A 974
LYS A 972
PRO A 973
None
1.18A 4dv1L-5me3A:
undetectable
4dv1L-5me3A:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 7 LEU A 517
THR A 513
ILE A 433
GLY A 428
None
0.93A 4eq4A-5me3A:
undetectable
4eq4A-5me3A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 7 LEU A 517
THR A 513
ILE A 433
GLY A 428
None
0.94A 4eqlA-5me3A:
undetectable
4eqlA-5me3A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 7 LEU A 517
THR A 513
ILE A 433
GLY A 428
None
0.96A 4eqlB-5me3A:
undetectable
4eqlB-5me3A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 7 ILE A 486
LEU A 490
PHE A 504
GLY A 555
None
0.83A 4hbfA-5me3A:
undetectable
4hbfA-5me3A:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 7 ILE A 486
LEU A 490
PHE A 504
GLY A 555
None
0.75A 4hc3A-5me3A:
undetectable
4hc3A-5me3A:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 11 LEU A 689
SER A 692
LEU A 709
LEU A 535
LEU A 693
None
1.36A 4or0A-5me3A:
undetectable
4or0A-5me3A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 11 LEU A 689
SER A 692
LEU A 709
LEU A 535
LEU A 693
None
1.33A 4or0B-5me3A:
undetectable
4or0B-5me3A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 8 PHE A1315
LEU A1272
LEU A1298
PHE A1297
None
0.95A 4qopC-5me3A:
undetectable
4qopC-5me3A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 LEU A 531
ILE A 559
GLY A 560
VAL A 690
LEU A 553
None
1.12A 4y8wB-5me3A:
undetectable
4y8wB-5me3A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 5 GLY A1275
ARG A1277
GLY A1279
GLU A1281
None
1.09A 4z2eB-5me3A:
undetectable
4z2eC-5me3A:
undetectable
4z2eB-5me3A:
18.10
4z2eC-5me3A:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 LEU A1241
LEU A1344
PHE A1297
THR A1242
THR A1322
None
1.18A 5bykA-5me3A:
undetectable
5bykA-5me3A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 5 GLU A1393
ALA A1392
GLU A1335
ASN A1333
None
1.43A 5dwkC-5me3A:
2.5
5dwkC-5me3A:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
4 / 7 ILE A 706
ILE A 713
THR A 728
ILE A 729
None
0.70A 5fukA-5me3A:
undetectable
5fukB-5me3A:
undetectable
5fukA-5me3A:
12.18
5fukB-5me3A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 12 THR A1054
LEU A1052
ALA A1053
ILE A1098
LEU A1086
None
0.96A 5gs4A-5me3A:
undetectable
5gs4A-5me3A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
3 / 3 TYR A 438
TYR A 601
SER A 605
None
0.92A 5iktB-5me3A:
0.9
5iktB-5me3A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
3 / 3 MET A1411
GLN A1414
ARG A1409
None
1.13A 5m35B-5me3A:
4.1
5m35B-5me3A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
3 / 3 MET A1411
GLN A1414
ARG A1409
None
1.10A 5m36A-5me3A:
4.4
5m36A-5me3A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 9 VAL A1369
PHE A1324
MET A1362
LEU A1345
ILE A1341
None
1.46A 5mzpA-5me3A:
1.7
5mzpA-5me3A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 10 TYR A 795
ILE A 800
VAL A 796
TYR A 758
ILE A 782
None
1.40A 5u98A-5me3A:
undetectable
5u98A-5me3A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 10 TYR A 795
ILE A 800
VAL A 796
TYR A 758
ILE A 782
None
1.41A 5u98D-5me3A:
undetectable
5u98D-5me3A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9H_R_ADNR400_1
(CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
5 / 10 VAL A1369
PHE A1324
MET A1362
LEU A1345
ILE A1341
None
1.29A 6d9hR-5me3A:
3.7
6d9hR-5me3A:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
3 / 3 MET A1411
GLN A1414
ARG A1409
None
1.14A 6fnaB-5me3A:
3.6
6fnaB-5me3A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii)
3 / 3 MET A1411
GLN A1414
ARG A1409
None
1.13A 6fnbA-5me3A:
3.3
6fnbA-5me3A:
12.38