SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5meb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 5meb CELL DIVISION CYCLE
PROTEIN CDT1
(Saccharomyces
cerevisiae) 		5 / 10 ALA A 554
LEU A 523
LEU A 520
SER A 555
LEU A 558
 None
 1.25A 2ceoB-5mebA:
undetectable		 2ceoB-5mebA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 5meb CELL DIVISION CYCLE
PROTEIN CDT1
(Saccharomyces
cerevisiae) 		3 / 3 GLN A 596
ASP A 604
GLN A 603
 None
 0.89A 4aztA-5mebA:
undetectable		 4aztA-5mebA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 5meb CELL DIVISION CYCLE
PROTEIN CDT1
(Saccharomyces
cerevisiae) 		5 / 12 SER A 541
ILE A 519
TRP A 583
LEU A 586
LEU A 558
 None
 1.11A 4foxB-5mebA:
undetectable		 4foxB-5mebA:
17.49