SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mec'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 5mec CELL DIVISION CYCLE
PROTEIN CDT1
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 327
LEU A 343
MET A 350
 None
 0.81A 1ya3B-5mecA:
undetectable		 1ya3B-5mecA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KIV_A_ACAA100_1
(APOLIPOPROTEIN)		 5mec CELL DIVISION CYCLE
PROTEIN CDT1
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 399
ASP A 369
TRP A 367
PHE A 318
 None
 1.19A 3kivA-5mecA:
undetectable		 3kivA-5mecA:
16.27