SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mf1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 5mf1 FUSION PROTEIN
HAP2/GCS1
(Chlamydomonas
reinhardtii) 		3 / 3 SER A 513
THR A 572
PHE A 485
 None
 0.72A 2x91A-5mf1A:
undetectable		 2x91A-5mf1A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 5mf1 FUSION PROTEIN
HAP2/GCS1
(Chlamydomonas
reinhardtii) 		3 / 3 SER A 160
ARG A 377
GLN A 161
 None
 0.69A 2xnrA-5mf1A:
undetectable		 2xnrA-5mf1A:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 5mf1 FUSION PROTEIN
HAP2/GCS1
(Chlamydomonas
reinhardtii) 		5 / 10 PHE A 163
GLY A 162
PHE A 376
LEU A 391
THR A 212
 None
 1.13A 3a3yA-5mf1A:
undetectable		 3a3yA-5mf1A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5mf1 FUSION PROTEIN
HAP2/GCS1
(Chlamydomonas
reinhardtii) 		4 / 7 GLN A 394
GLY A 363
GLY A 370
ALA A 375
 None
 0.68A 3fpjB-5mf1A:
undetectable		 3fpjB-5mf1A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 5mf1 FUSION PROTEIN
HAP2/GCS1
(Chlamydomonas
reinhardtii) 		4 / 5 ARG A 348
LEU A 324
PRO A 327
VAL A 326
 None
 1.13A 3ufnA-5mf1A:
undetectable
3ufnB-5mf1A:
undetectable		 3ufnA-5mf1A:
10.99
3ufnB-5mf1A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 5mf1 FUSION PROTEIN
HAP2/GCS1
(Chlamydomonas
reinhardtii) 		5 / 12 HIS A 287
PRO A 293
LEU A 306
PHE A 230
ILE A 232
 None
 1.29A 5dv4A-5mf1A:
undetectable		 5dv4A-5mf1A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5mf1 FUSION PROTEIN
HAP2/GCS1
(Chlamydomonas
reinhardtii) 		5 / 12 ALA A 473
PHE A 477
GLY A 409
GLY A 484
GLY A 421
 NAG  A1001 (-4.0A)
None
None
None
None
 1.32A 5i71A-5mf1A:
undetectable		 5i71A-5mf1A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5mf1 FUSION PROTEIN
HAP2/GCS1
(Chlamydomonas
reinhardtii) 		5 / 12 ASP A 547
GLU A 546
LEU A 571
THR A 572
LEU A 543
 None
 1.25A 5ogcB-5mf1A:
undetectable		 5ogcB-5mf1A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 5mf1 FUSION PROTEIN
HAP2/GCS1
(Chlamydomonas
reinhardtii) 		5 / 12 ILE A 232
LEU A 228
LEU A 103
THR A 450
LEU A 451
 None
 1.02A 6b54A-5mf1A:
undetectable		 6b54A-5mf1A:
15.35